STRINGSTRING
Marveld3 Marveld3 Ptpn5 Ptpn5 Rgs2 Rgs2 Nf2 Nf2 Hmgcr Hmgcr Dusp27 Dusp27 Slc9a3r1 Slc9a3r1 Ranbp9 Ranbp9 Epha4 Epha4 Igf1r Igf1r Phb Phb Mast3 Mast3 Rapgef1 Rapgef1 Apoe Apoe Nf1 Nf1 Gba Gba Dusp2 Dusp2 Ephb2 Ephb2 Spred2 Spred2 Hdac3 Hdac3 Ncor1 Ncor1 Tlr9 Tlr9 Fktn Fktn Adipoq Adipoq Lmo3 Lmo3 Eif3a Eif3a Pparg Pparg Sfrp4 Sfrp4 Dusp5 Dusp5 Csk Csk Irak3 Irak3 Ace2 Ace2 Tsc2 Tsc2 Paqr3 Paqr3 Sh3rf2 Sh3rf2 Nppa Nppa Igbp1 Igbp1 Itgb1bp1 Itgb1bp1 Chrna9 Chrna9 Lax1 Lax1 Nup62 Nup62 Foxm1 Foxm1 Dusp19 Dusp19 Ezr Ezr Foxo1 Foxo1 Inpp5k Inpp5k Ptprc Ptprc Rgs14 Rgs14 Phlpp1 Phlpp1 Pebp1 Pebp1 Apc Apc Potea Potea Dusp1 Dusp1 Emilin1 Emilin1 Pdcd4 Pdcd4 Dusp4 Dusp4 E130311K13Rik E130311K13Rik Pebp1-2 Pebp1-2 Aida Aida LOC105995785 LOC105995785 Sfrp1 Sfrp1 Dupd1 Dupd1 Dab2 Dab2 Tbc1d10c Tbc1d10c Fbln1 Fbln1 Klhl31 Klhl31 LOC106002419 LOC106002419 Tnip1 Tnip1 Prkcd Prkcd Itch Itch Rps6ka6 Rps6ka6 Dusp13 Dusp13 Dusp16 Dusp16 Chrna10 Chrna10 Arrb1 Arrb1 Psca Psca Ash1l Ash1l Dag1 Dag1 Timp3 Timp3 Dusp9 Dusp9 LOC105990085 LOC105990085 LOC105990162 LOC105990162 Pafah1b1 Pafah1b1 Dmd Dmd Per1 Per1 Spry2 Spry2 ENSDORP00000022042 ENSDORP00000022042 Smpd1 Smpd1 Errfi1 Errfi1 Psmd10 Psmd10 Dab2ip Dab2ip Trem2 Trem2 Cd300a Cd300a Gsk3b Gsk3b Sorl1 Sorl1 Atf3 Atf3 Mecom Mecom Uchl1 Uchl1 F2rl1 F2rl1 Dusp3 Dusp3 Spred1 Spred1 Mapk8ip1 Mapk8ip1 Ptpn2 Ptpn2 Insr Insr Prdm15 Prdm15 Spry1 Spry1 Dusp6 Dusp6 Ptpn1 Ptpn1 ENSDORP00000025030 ENSDORP00000025030 Zmynd11 Zmynd11 Wnk2 Wnk2 Gper1 Gper1 Cryba1 Cryba1 Spry4 Spry4 ENSDORP00000025871 ENSDORP00000025871 LOC105993437 LOC105993437 Ptprj Ptprj Sfrp2 Sfrp2 Lif Lif ENSDORP00000026609 ENSDORP00000026609 Cav3 Cav3 Prmt1 Prmt1 Chrna7 Chrna7 Cyld Cyld Men1 Men1 Sema6a Sema6a Dusp26 Dusp26 Efna1 Efna1 Cav1 Cav1 Vrk3 Vrk3 LOC105989276 LOC105989276 Lemd2 Lemd2 Taok3 Taok3 Tlr4 Tlr4 Ptpn6 Ptpn6 Abca7 Abca7 Ptprr Ptprr Lyn Lyn Gps2 Gps2 Smad4 Smad4 Il1b Il1b Ankrd26 Ankrd26 Synj2bp Synj2bp Bmp4 Bmp4 Dusp10 Dusp10 Bmp2 Bmp2 Flcn Flcn Inppl1 Inppl1 Agt Agt Pten Pten Tmem130 Tmem130 Hipk3 Hipk3 C1ql4 C1ql4 Sfrp5 Sfrp5 Ndrg2 Ndrg2 Qars Qars Rnf149 Rnf149 Spred3 Spred3 Pin1 Pin1 Dusp7 Dusp7 Pik3cb Pik3cb Akt1 Akt1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Marveld3MARVEL domain-containing protein 3. (254 aa)
Ptpn5Tyrosine-protein phosphatase non-receptor type 5 isoform X1. (369 aa)
Rgs2Regulator of G-protein signaling 2. (211 aa)
Nf2Merlin isoform X1. (596 aa)
Hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductase. (404 aa)
Dusp27Inactive dual specificity phosphatase 27; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (1144 aa)
Slc9a3r1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (359 aa)
Ranbp9Ran-binding protein 9. (685 aa)
Epha4Ephrin type-A receptor 4 isoform X1. (986 aa)
Igf1rTyrosine-protein kinase receptor. (923 aa)
PhbProhibitin. (272 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Rapgef1Rap guanine nucleotide exchange factor 1 isoform X1. (1198 aa)
ApoeApolipoprotein E. (274 aa)
Nf1Neurofibromin isoform X1. (2841 aa)
GbaGlucosylceramidase. (515 aa)
Dusp2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (318 aa)
Ephb2Ephrin type-B receptor 2 isoform X2. (1018 aa)
Spred2Sprouty-related, EVH1 domain-containing protein 2 isoform X2. (421 aa)
Hdac3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (432 aa)
Ncor1Nuclear receptor corepressor 1. (1652 aa)
Tlr9Toll-like receptor 9 isoform X3. (1029 aa)
FktnFukutin isoform X1. (461 aa)
AdipoqAdiponectin. (251 aa)
Lmo3LIM domain only protein 3. (145 aa)
Eif3aEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1338 aa)
PpargPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
Sfrp4Secreted frizzled-related protein 4 isoform X2. (357 aa)
Dusp5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
CskTyrosine-protein kinase. (450 aa)
Irak3Interleukin-1 receptor-associated kinase 3. (587 aa)
Ace2Angiotensin-converting enzyme. (805 aa)
Tsc2Tuberin isoform X1. (1809 aa)
Paqr3Progestin and adipoQ receptor family member 3. (311 aa)
Sh3rf2Putative E3 ubiquitin-protein ligase SH3RF2 isoform X1. (726 aa)
NppaNatriuretic peptides A. (153 aa)
Igbp1Immunoglobulin-binding protein 1. (340 aa)
Itgb1bp1Integrin beta-1-binding protein 1. (200 aa)
Chrna9Neuronal acetylcholine receptor subunit alpha-9. (479 aa)
Lax1Lymphocyte transmembrane adapter 1. (399 aa)
Nup62Nuclear pore glycoprotein p62. (512 aa)
Foxm1Forkhead box protein M1. (717 aa)
Dusp19Dual specificity protein phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (221 aa)
EzrEzrin isoform X1. (583 aa)
Foxo1Forkhead box protein O1. (537 aa)
Inpp5kInositol polyphosphate 5-phosphatase K. (405 aa)
PtprcReceptor-type tyrosine-protein phosphatase C isoform X1. (1252 aa)
Rgs14Regulator of G-protein signaling 14. (551 aa)
Phlpp1PH domain leucine-rich repeat-containing protein phosphatase 1. (1448 aa)
Pebp1Phosphatidylethanolamine binding protein 1. (157 aa)
ApcAdenomatous polyposis coli protein isoform X2. (2842 aa)
PoteaPOTE ankyrin domain family member A. (116 aa)
Dusp1Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (244 aa)
Emilin1EMILIN-1. (1015 aa)
Pdcd4Programmed cell death protein 4 isoform X1. (469 aa)
Dusp4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (395 aa)
E130311K13RikProtein C3orf33 homolog. (253 aa)
Pebp1-2Phosphatidylethanolamine-binding protein 1. (203 aa)
AidaAxin interactor, dorsalization-associated protein isoform X1. (306 aa)
LOC105995785Non-specific serine/threonine protein kinase. (204 aa)
Sfrp1Secreted frizzled-related protein 1. (314 aa)
Dupd1Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (215 aa)
Dab2Disabled homolog 2 isoform X4. (235 aa)
Tbc1d10cCarabin isoform X1. (441 aa)
Fbln1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (703 aa)
Klhl31Kelch-like protein 31. (390 aa)
LOC106002419Uncharacterized LOC106002419. (92 aa)
Tnip1TNFAIP3-interacting protein 1 isoform X1. (653 aa)
PrkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ItchE3 ubiquitin-protein ligase. (857 aa)
Rps6ka6Ribosomal protein S6 kinase. (836 aa)
Dusp13Dual specificity protein phosphatase 13 isoform B-like; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (239 aa)
Dusp16Dual specificity phosphatase 16. (339 aa)
Chrna10Neuronal acetylcholine receptor subunit alpha-10. (447 aa)
Arrb1Beta-arrestin-1 isoform X1. (411 aa)
PscaProstate stem cell antigen isoform X3. (123 aa)
Ash1lHistone-lysine N-methyltransferase ASH1L. (2971 aa)
Dag1Dystroglycan. (891 aa)
Timp3Metalloproteinase inhibitor 3. (211 aa)
Dusp9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
LOC105990085Tyrosine-protein phosphatase non-receptor type. (333 aa)
LOC105990162Prohibitin pseudogene. (194 aa)
Pafah1b1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
DmdDystrophin isoform X3. (617 aa)
Per1Period circadian protein homolog 1 isoform X1. (827 aa)
Spry2Protein sprouty homolog 2. (315 aa)
ENSDORP00000022042annotation not available (263 aa)
Smpd1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
Errfi1ERBB receptor feedback inhibitor 1. (446 aa)
Psmd1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (193 aa)
Dab2ipDisabled homolog 2-interacting protein isoform X1. (1166 aa)
Trem2Triggering receptor expressed on myeloid cells 2. (251 aa)
Cd300aCMRF35-like molecule 8. (300 aa)
Gsk3bGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
Sorl1Sortilin-related receptor. (2145 aa)
Atf3Cyclic AMP-dependent transcription factor ATF-3 isoform X1. (181 aa)
MecomMDS1 and EVI1 complex locus protein EVI1 isoform X2. (1047 aa)
Uchl1Ubiquitin carboxyl-terminal hydrolase. (223 aa)
F2rl1Proteinase-activated receptor 2. (397 aa)
Dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
Spred1Sprouty-related, EVH1 domain-containing protein 1. (436 aa)
Mapk8ip1C-Jun-amino-terminal kinase-interacting protein 1. (680 aa)
Ptpn2Tyrosine-protein phosphatase non-receptor type 2. (397 aa)
InsrTyrosine-protein kinase receptor. (1183 aa)
Prdm15PR domain zinc finger protein 15. (1227 aa)
Spry1Protein sprouty homolog 1. (317 aa)
Dusp6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
Ptpn1Tyrosine-protein phosphatase non-receptor type. (436 aa)
ENSDORP00000025030annotation not available (352 aa)
Zmynd11Zinc finger MYND domain-containing protein 11 isoform X2. (602 aa)
Wnk2Serine/threonine-protein kinase WNK2 isoform X1. (2221 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
Cryba1Beta-crystallin A3; Belongs to the beta/gamma-crystallin family. (216 aa)
Spry4Protein sprouty homolog 4. (300 aa)
ENSDORP00000025871annotation not available (284 aa)
LOC105993437LOW QUALITY PROTEIN: dystrophin-like. (776 aa)
PtprjReceptor-type tyrosine-protein phosphatase eta. (1205 aa)
Sfrp2Secreted frizzled-related protein 2. (296 aa)
LifLeukemia inhibitory factor. (202 aa)
ENSDORP00000026609annotation not available (153 aa)
Cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
Prmt1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
Chrna7Neuronal acetylcholine receptor subunit alpha-7. (568 aa)
CyldUbiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family. (957 aa)
Men1Menin isoform X2. (610 aa)
Sema6asemaphorin-6A; Belongs to the semaphorin family. (601 aa)
Dusp26Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa)
Efna1ephrin-A1; Belongs to the ephrin family. (203 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
Vrk3Inactive serine/threonine-protein kinase VRK3. (453 aa)
LOC105989276Glutathione S-transferase P; Belongs to the GST superfamily. (210 aa)
Lemd2LEM domain-containing protein 2 isoform X2. (490 aa)
Taok3Serine/threonine-protein kinase TAO3 isoform X1. (898 aa)
Tlr4Toll-like receptor 4 isoform X2; Belongs to the Toll-like receptor family. (842 aa)
Ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
Abca7ATP-binding cassette sub-family A member 7. (1849 aa)
PtprrReceptor-type tyrosine-protein phosphatase R isoform X2. (411 aa)
LynTyrosine-protein kinase. (512 aa)
Gps2G protein pathway suppressor 2. (327 aa)
Smad4Mothers against decapentaplegic homolog. (528 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Ankrd26Ankyrin repeat domain-containing protein 30A isoform X2. (1628 aa)
Synj2bpSynaptojanin-2-binding protein. (145 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
Dusp10Dual specificity protein phosphatase 10. (482 aa)
Bmp2Bone morphogenetic protein 2. (398 aa)
FlcnFolliculin. (579 aa)
Inppl1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1240 aa)
AgtAngiotensinogen; Belongs to the serpin family. (473 aa)
PtenPhosphatase and tensin homolog. (396 aa)
Tmem130Transmembrane protein 130 isoform X2. (345 aa)
Hipk3Homeodomain-interacting protein kinase 3. (1093 aa)
C1ql4Complement C1q-like protein 4. (238 aa)
Sfrp5Secreted frizzled-related protein 5. (311 aa)
Ndrg2Protein NDRG2 isoform X1. (371 aa)
Qarsglutamine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (259 aa)
Rnf149E3 ubiquitin-protein ligase RNF149 isoform X1. (394 aa)
Spred3Sprouty-related, EVH1 domain-containing protein 3. (407 aa)
Pin1Peptidyl-prolyl cis-trans isomerase. (165 aa)
Dusp7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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