44 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSDORP00000023223	annotation not available (74 aa)
	Setx	Probable helicase senataxin. (81 aa)
	Akt2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	Tnfsf11	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (319 aa)
	Igf1	Insulin-like growth factor I isoform X2. (130 aa)
	Ilk	Integrin-linked protein kinase isoform X1. (452 aa)
	Sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (383 aa)
	Mertk	Tyrosine-protein kinase Mer. (947 aa)
	Bank1	B-cell scaffold protein with ankyrin repeats. (783 aa)
	Rapgef1	Rap guanine nucleotide exchange factor 1 isoform X1. (1198 aa)
	Tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (130 aa)
	Plk3	Serine/threonine-protein kinase PLK. (647 aa)
	Akt1	Non-specific serine/threonine protein kinase. (188 aa)
	Pax2	Paired box protein Pax-2 isoform X2. (417 aa)
	Pik3c2b	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1; Belongs to the PI3/PI4-kinase family. (1628 aa)
	Kdr	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1352 aa)
	Pten	Phosphatase and tensin homolog. (396 aa)
	Pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	Il1b	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
	Flcn	Folliculin. (579 aa)
	LOC106001479	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (492 aa)
	Gas6	Growth arrest-specific protein 6. (660 aa)
	Tnf	Tumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (220 aa)
	Pear1	Platelet endothelial aggregation receptor 1. (1027 aa)
	Drd2	D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	Tsc2	Tuberin isoform X1. (1809 aa)
	Smpd3	Sphingomyelin phosphodiesterase 3. (653 aa)
	Cd40	Tumor necrosis factor receptor superfamily member 5 isoform X1. (279 aa)
	Adtrp	Androgen-dependent TFPI-regulating protein isoform X1. (234 aa)
	C1qtnf12	Adipolin. (252 aa)
	Pik3r3	Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
	Epha2	Ephrin type-A receptor 2 isoform X2. (976 aa)
	Sesn2	Sestrin-2. (480 aa)
	Nrg1	Pro-neuregulin-1, membrane-bound isoform isoform X1. (700 aa)
	Fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
	Nkx3-1	Homeobox protein Nkx-3.1. (138 aa)
	Tmem100	Transmembrane protein 100. (134 aa)
	Lingo1	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1. (617 aa)
	Stk3	Serine/threonine-protein kinase 3. (491 aa)
	Mt3	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (69 aa)
	Rps6kb2	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
	Axl	Tyrosine-protein kinase receptor UFO. (858 aa)
	P2ry12	p2Y purinoceptor 12. (341 aa)
	Lox	Protein-lysine 6-oxidase isoform X2. (214 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akt1	Akt2	ENSDORP00000005559	ENSDORP00000026851	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.967
Akt1	ENSDORP00000023223	ENSDORP00000005559	ENSDORP00000023223	Non-specific serine/threonine protein kinase.	annotation not available	0.898
Akt1	Gas6	ENSDORP00000005559	ENSDORP00000011367	Non-specific serine/threonine protein kinase.	Growth arrest-specific protein 6.	0.604
Akt1	Il1b	ENSDORP00000005559	ENSDORP00000009309	Non-specific serine/threonine protein kinase.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.578
Akt1	Ilk	ENSDORP00000005559	ENSDORP00000000485	Non-specific serine/threonine protein kinase.	Integrin-linked protein kinase isoform X1.	0.978
Akt1	Kdr	ENSDORP00000005559	ENSDORP00000006407	Non-specific serine/threonine protein kinase.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.474
Akt1	LOC106001479	ENSDORP00000005559	ENSDORP00000010802	Non-specific serine/threonine protein kinase.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.898
Akt1	Lox	ENSDORP00000005559	ENSDORP00000025835	Non-specific serine/threonine protein kinase.	Protein-lysine 6-oxidase isoform X2.	0.576
Akt1	Mertk	ENSDORP00000005559	ENSDORP00000002086	Non-specific serine/threonine protein kinase.	Tyrosine-protein kinase Mer.	0.416
Akt1	Nkx3-1	ENSDORP00000005559	ENSDORP00000018983	Non-specific serine/threonine protein kinase.	Homeobox protein Nkx-3.1.	0.862
Akt1	Nrg1	ENSDORP00000005559	ENSDORP00000018178	Non-specific serine/threonine protein kinase.	Pro-neuregulin-1, membrane-bound isoform isoform X1.	0.423
Akt1	Pik3ca	ENSDORP00000005559	ENSDORP00000008976	Non-specific serine/threonine protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.974
Akt1	Pik3r3	ENSDORP00000005559	ENSDORP00000016327	Non-specific serine/threonine protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit gamma.	0.904
Akt1	Pten	ENSDORP00000005559	ENSDORP00000008384	Non-specific serine/threonine protein kinase.	Phosphatase and tensin homolog.	0.879
Akt1	Rps6kb2	ENSDORP00000005559	ENSDORP00000021063	Non-specific serine/threonine protein kinase.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.916
Akt1	Sirt2	ENSDORP00000005559	ENSDORP00000001437	Non-specific serine/threonine protein kinase.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.420
Akt1	Tgfb1	ENSDORP00000005559	ENSDORP00000003371	Non-specific serine/threonine protein kinase.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.656
Akt1	Tnf	ENSDORP00000005559	ENSDORP00000011715	Non-specific serine/threonine protein kinase.	Tumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family.	0.683
Akt1	Tsc2	ENSDORP00000005559	ENSDORP00000012885	Non-specific serine/threonine protein kinase.	Tuberin isoform X1.	0.932
Akt2	Akt1	ENSDORP00000026851	ENSDORP00000005559	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.967