STRINGSTRING
Th Th Chrna7 Chrna7 Nppc Nppc Rgs4 Rgs4 Adh7 Adh7 Usp46 Usp46 Myc Myc Slc6a3 Slc6a3 Kcnmb1 Kcnmb1 ENSDORP00000024970 ENSDORP00000024970 Glra1 Glra1 Rgs19 Rgs19 Insr Insr Bak1 Bak1 Cyp7a1 Cyp7a1 Srebf1 Srebf1 Cldn5 Cldn5 ENSDORP00000023223 ENSDORP00000023223 Tp53inp1 Tp53inp1 Adcyap1r1 Adcyap1r1 Grin1 Grin1 Itpr2 Itpr2 Tufm-2 Tufm-2 Gata3 Gata3 Slc23a2 Slc23a2 Rara Rara Drd3 Drd3 LOC105990162 LOC105990162 Vcam1 Vcam1 Vhl Vhl Sirt1 Sirt1 Cbl Cbl Abat Abat Cldn3 Cldn3 Hmgcs2 Hmgcs2 Cldn1 Cldn1 Crhr1 Crhr1 Chrnb2 Chrnb2 Gabbr1 Gabbr1 ENSDORP00000019242 ENSDORP00000019242 Adh1 Adh1 Cldn18 Cldn18 LOC105996339 LOC105996339 Tyms Tyms Nr0b2 Nr0b2 Ehmt2 Ehmt2 Adcyap1 Adcyap1 Eps8 Eps8 Eif4ebp1 Eif4ebp1 Ntrk3 Ntrk3 Fgfr2 Fgfr2 ENSDORP00000016358 ENSDORP00000016358 Ccnd1 Ccnd1 Tufm Tufm ENSDORP00000015336 ENSDORP00000015336 Prkcb Prkcb Glra3 Glra3 Dbh Dbh Csf3 Csf3 Arsa Arsa Got2 Got2 Ggh Ggh Il2 Il2 Prkaa1 Prkaa1 Crh Crh Drd2 Drd2 Hdac2 Hdac2 Lct Lct Adipoq Adipoq G6pd G6pd Glra2 Glra2 Cybb Cybb Grin3a Grin3a Cpt1a Cpt1a Mstn Mstn Grin2a Grin2a LOC106001479 LOC106001479 Maob Maob Psmd14 Psmd14 Ogg1 Ogg1 Slc2a4 Slc2a4 Sdf4 Sdf4 Nlrp3 Nlrp3 Adcy7 Adcy7 Prkce Prkce Birc2 Birc2 Eif4g1 Eif4g1 Prkca Prkca Ptk2b Ptk2b Atp5f1a Atp5f1a Tbxas1 Tbxas1 Pten Pten Cnr1 Cnr1 St6gal1 St6gal1 Gnrh1 Gnrh1 Setdb1 Setdb1 Hoxa1 Hoxa1 Rpl15 Rpl15 Dmap1 Dmap1 Rgs2 Rgs2 Cldn7 Cldn7 Myd88 Myd88 Aacs Aacs Igf1r Igf1r Rgs7 Rgs7 Phb Phb Lep Lep Tbxa2r Tbxa2r Unc79 Unc79 Eef1b2 Eef1b2 Ccl7 Ccl7 Alad Alad Polb Polb Oprm1 Oprm1 Crhbp Crhbp Bcl2 Bcl2 Abcb11 Abcb11 Bad Bad Grin2b Grin2b Actr2 Actr2 Tlr4 Tlr4 Ca3 Ca3 Pth Pth Kcnc2 Kcnc2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ThTyrosine 3-monooxygenase isoform X1. (519 aa)
Chrna7Neuronal acetylcholine receptor subunit alpha-7. (568 aa)
NppcC-type natriuretic peptide. (126 aa)
Rgs4Regulator of G-protein signaling 4 isoform X1. (205 aa)
Adh7Alcohol dehydrogenase class 4 mu/sigma chain. (374 aa)
Usp46Ubiquitin carboxyl-terminal hydrolase 46 isoform X1; Belongs to the peptidase C19 family. (366 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
Slc6a3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (635 aa)
Kcnmb1Calcium-activated potassium channel subunit beta-1. (191 aa)
ENSDORP00000024970annotation not available (187 aa)
Glra1Glycine receptor subunit alpha-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
Rgs19Regulator of G-protein signaling 19 isoform X1. (217 aa)
InsrTyrosine-protein kinase receptor. (1183 aa)
Bak1Bcl-2 homologous antagonist/killer. (211 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (508 aa)
Srebf1Sterol regulatory element-binding protein 1 isoform X1. (1126 aa)
Cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
ENSDORP00000023223annotation not available (74 aa)
Tp53inp1Tumor protein p53-inducible nuclear protein 1 isoform X1. (240 aa)
Adcyap1r1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (610 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2678 aa)
Tufm-2Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
Slc23a2Solute carrier family 23 member 2 isoform X1. (650 aa)
RaraRetinoic acid receptor alpha. (343 aa)
Drd3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (445 aa)
LOC105990162Prohibitin pseudogene. (194 aa)
Vcam1Vascular cell adhesion protein 1. (739 aa)
VhlVon Hippel-Lindau disease tumor suppressor. (204 aa)
Sirt1NAD-dependent protein deacetylase sirtuin-1. (646 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
Abat4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
Cldn3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
Hmgcs23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
Cldn1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
Crhr1Corticotropin-releasing factor receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (415 aa)
Chrnb2Neuronal acetylcholine receptor subunit beta-2 isoform X1. (504 aa)
Gabbr1Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (961 aa)
ENSDORP00000019242annotation not available (209 aa)
Adh1Alcohol dehydrogenase 1C. (301 aa)
Cldn18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (264 aa)
LOC105996339Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
TymsThymidylate synthase. (296 aa)
Nr0b2Nuclear receptor subfamily 0 group B member 2. (260 aa)
Ehmt2Histone-lysine N-methyltransferase EHMT2. (994 aa)
Adcyap1Pituitary adenylate cyclase-activating polypeptide. (176 aa)
Eps8Epidermal growth factor receptor kinase substrate 8. (193 aa)
Eif4ebp1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
Ntrk3Tyrosine-protein kinase receptor. (864 aa)
Fgfr2Fibroblast growth factor receptor. (819 aa)
ENSDORP00000016358annotation not available (337 aa)
Ccnd1G1/S-specific cyclin-D1. (156 aa)
TufmTu translation elongation factor, mitochondrial. (117 aa)
ENSDORP00000015336annotation not available (189 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
Glra3Glycine receptor subunit alpha-3 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
DbhDopamine beta-hydroxylase. (620 aa)
Csf3Granulocyte colony-stimulating factor isoform X2. (205 aa)
ArsaArylsulfatase A isoform X1. (507 aa)
Got2Aspartate aminotransferase. (428 aa)
GghFolate gamma-glutamyl hydrolase. (316 aa)
Il2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
Prkaa1Non-specific serine/threonine protein kinase. (538 aa)
CrhCorticoliberin. (188 aa)
Drd2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
LctLactase-phlorizin hydrolase. (1927 aa)
AdipoqAdiponectin. (251 aa)
G6pdGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (535 aa)
Glra2Glycine receptor subunit alpha-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
CybbCytochrome b-245 heavy chain. (570 aa)
Grin3aGlutamate receptor ionotropic, NMDA 3A isoform X1. (1134 aa)
Cpt1aCarnitine O-palmitoyltransferase 1, liver isoform; Belongs to the carnitine/choline acetyltransferase family. (775 aa)
MstnGrowth/differentiation factor 8. (376 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1301 aa)
LOC106001479Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (492 aa)
MaobAmine oxidase. (520 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
Ogg1N-glycosylase/DNA lyase. (262 aa)
Slc2a4Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
Sdf445 kDa calcium-binding protein. (190 aa)
Nlrp3NACHT, LRR and PYD domains-containing protein 3. (1027 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
PrkceProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (548 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (573 aa)
Eif4g1Eukaryotic translation initiation factor 4 gamma 1 isoform X2. (1306 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
Atp5f1aATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
Tbxas1thromboxane-A synthase; Belongs to the cytochrome P450 family. (457 aa)
PtenPhosphatase and tensin homolog. (396 aa)
Cnr1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (471 aa)
St6gal1Beta-galactoside alpha-2,6-sialyltransferase 1 isoform X1; Belongs to the glycosyltransferase 29 family. (406 aa)
Gnrh1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (89 aa)
Setdb1Histone-lysine N-methyltransferase SETDB1. (1287 aa)
Hoxa1Homeobox protein Hox-A1 isoform X1. (338 aa)
Rpl15Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
Dmap1DNA methyltransferase 1-associated protein 1 isoform X1. (468 aa)
Rgs2Regulator of G-protein signaling 2. (211 aa)
Cldn7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (338 aa)
Aacsacetoacetyl-CoA synthetase. (574 aa)
Igf1rTyrosine-protein kinase receptor. (923 aa)
Rgs7Regulator of G-protein signaling 7 isoform X3. (477 aa)
PhbProhibitin. (272 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Tbxa2rCactin-like. (354 aa)
Unc79Protein unc-79 homolog isoform X2. (2643 aa)
Eef1b2Elongation factor 1-beta-like; Belongs to the EF-1-beta/EF-1-delta family. (213 aa)
Ccl7C-C motif chemokine. (98 aa)
AladDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)
PolbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (195 aa)
Oprm1Mu-type opioid receptor isoform X3; Belongs to the G-protein coupled receptor 1 family. (391 aa)
CrhbpCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
Abcb11Bile salt export pump. (1261 aa)
BadBcl2-associated agonist of cell death isoform X1. (154 aa)
Grin2bGlutamate receptor ionotropic, NMDA 2B. (1103 aa)
Actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
Tlr4Toll-like receptor 4 isoform X2; Belongs to the Toll-like receptor family. (842 aa)
Ca3Carbonic anhydrase 3; Belongs to the alpha-carbonic anhydrase family. (260 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
Kcnc2Potassium voltage-gated channel subfamily C member 2 isoform X1; Belongs to the potassium channel family. (422 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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