STRINGSTRING
Met Met Sh2b1 Sh2b1 Edn1 Edn1 Pdgfrb Pdgfrb Fgf8 Fgf8 Prap1 Prap1 ENSDORP00000022059 ENSDORP00000022059 Tgfa Tgfa Pdgfb Pdgfb Drd3 Drd3 Igf2 Igf2 Anapc11 Anapc11 Igf1 Igf1 Egf Egf Anapc7 Anapc7 Cenpe Cenpe Igf1r Igf1r Cul3 Cul3 Hoxa13 Hoxa13 Dmrt1 Dmrt1 Anapc5 Anapc5 Ereg Ereg Nsmce2 Nsmce2 Il1b Il1b Cdc16 Cdc16 Phip Phip Cd28 Cd28 Epgn Epgn Nup62 Nup62 Rgcc Rgcc Smpd3 Smpd3 Cdc23 Cdc23 Btc Btc Nusap1 Nusap1 Cdt1 Cdt1 Cdc27 Cdc27 Mad2l1bp Mad2l1bp Lrp5 Lrp5 Edn3 Edn3 Il1a Il1a Sphk1 Sphk1 Rb1 Rb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MetHepatocyte growth factor receptor. (1382 aa)
Sh2b1SH2B adapter protein 1 isoform X3. (726 aa)
Edn1Endothelin-1-like isoform X1. (202 aa)
PdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa)
Fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
Prap1Proline-rich acidic protein 1. (80 aa)
ENSDORP00000022059annotation not available (176 aa)
TgfaProtransforming growth factor alpha. (156 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
Drd3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (445 aa)
Igf2Insulin-like growth factor II. (176 aa)
Anapc11Anaphase-promoting complex subunit 11. (84 aa)
Igf1Insulin-like growth factor I isoform X2. (130 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (664 aa)
Anapc7Anaphase-promoting complex subunit 7. (433 aa)
CenpeCentromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2437 aa)
Igf1rTyrosine-protein kinase receptor. (923 aa)
Cul3Cullin-3 isoform X1; Belongs to the cullin family. (762 aa)
Hoxa13Homeobox protein Hox-A13. (217 aa)
Dmrt1Doublesex- and mab-3-related transcription factor 1. (208 aa)
Anapc5Anaphase-promoting complex subunit 5 isoform X3. (410 aa)
EregProepiregulin. (163 aa)
Nsmce2E3 SUMO-protein ligase NSE2 isoform X2. (246 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Cdc16Cell division cycle protein 16 homolog. (620 aa)
PhipPH-interacting protein isoform X1. (1758 aa)
Cd28T-cell-specific surface glycoprotein CD28. (219 aa)
EpgnEpigen isoform X5. (153 aa)
Nup62Nuclear pore glycoprotein p62. (512 aa)
RgccRegulator of cell cycle RGCC. (138 aa)
Smpd3Sphingomyelin phosphodiesterase 3. (653 aa)
Cdc23Cell division cycle protein 23 homolog. (597 aa)
BtcProbetacellulin. (163 aa)
Nusap1Nucleolar and spindle-associated protein 1. (323 aa)
Cdt1DNA replication factor Cdt1. (386 aa)
Cdc27Cell division cycle protein 27 homolog isoform X1. (825 aa)
Mad2l1bpMAD2L1-binding protein. (170 aa)
Lrp5Low-density lipoprotein receptor-related protein 5. (1616 aa)
Edn3Endothelin-3. (206 aa)
Il1aInterleukin-1; Belongs to the IL-1 family. (270 aa)
Sphk1Sphingosine kinase 1. (372 aa)
Rb1Retinoblastoma-associated protein isoform X1. (926 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.