STRINGSTRING
Egr1 Egr1 Nptn Nptn Synpo Synpo Camk2g Camk2g Kdr Kdr Kit Kit Snca Snca Neurl1 Neurl1 Agt Agt Synpr Synpr Nf1 Nf1 Grin2a Grin2a Kcnj10 Kcnj10 Ephb2 Ephb2 Fmr1 Fmr1 Drd2 Drd2 Camk2b Camk2b Syngr1 Syngr1 Syp Syp Grik2 Grik2 ENSDORP00000018707 ENSDORP00000018707 Rab11a Rab11a Syngap1 Syngap1 LOC106002162 LOC106002162 Dlg4 Dlg4 Grin1 Grin1 Rab5a Rab5a Shank3 Shank3 LOC105996454 LOC105996454 App App
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa)
NptnNeuroplastin. (397 aa)
SynpoSynaptopodin isoform X1. (926 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma. (515 aa)
KdrVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1352 aa)
KitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
SncaAlpha-synuclein; Belongs to the synuclein family. (140 aa)
Neurl1E3 ubiquitin-protein ligase NEURL1 isoform X1. (574 aa)
AgtAngiotensinogen; Belongs to the serpin family. (473 aa)
SynprSynaptoporin isoform X1. (285 aa)
Nf1Neurofibromin isoform X1. (2841 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1301 aa)
Kcnj10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
Ephb2Ephrin type-B receptor 2 isoform X2. (1018 aa)
Fmr1Fragile X mental retardation protein 1 isoform X1. (616 aa)
Drd2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta. (644 aa)
Syngr1Synaptogyrin-1. (240 aa)
SypSynaptophysin. (313 aa)
Grik2Glutamate receptor ionotropic, kainate 2 isoform X1. (908 aa)
ENSDORP00000018707annotation not available (208 aa)
Rab11aRas-related protein Rab-11A. (86 aa)
Syngap1ras/Rap GTPase-activating protein SynGAP. (1343 aa)
LOC106002162Disks large homolog 4-like. (150 aa)
Dlg4Disks large homolog 4; Belongs to the MAGUK family. (657 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
Rab5aRas-related protein Rab-5A. (215 aa)
Shank3SH3 and multiple ankyrin repeat domains protein 3. (1417 aa)
LOC105996454Low affinity immunoglobulin gamma Fc region receptor II-like. (311 aa)
AppAmyloid beta A4 protein isoform X1. (770 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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