STRINGSTRING
Bmp2 Bmp2 Cdkn1b Cdkn1b Sod2 Sod2 LOC105989276 LOC105989276 Ndrg4 Ndrg4 Ogn Ogn Tnfaip3 Tnfaip3 Cnn1 Cnn1 Pparg Pparg Apoe Apoe Comt Comt Igfbp3 Igfbp3 Npr1 Npr1 Ptgir Ptgir Apln Apln Il12b Il12b Ndrg2 Ndrg2 Igfbp5 Igfbp5 Prkg1 Prkg1 Pten Pten Ppard Ppard Bmpr2 Bmpr2 Efemp2 Efemp2 Il10 Il10 S1pr2 S1pr2 Adipoq Adipoq Tgfb3 Tgfb3 Npr3 Npr3 Ace2 Ace2 Hmox1 Hmox1 Vip Vip Ppargc1a Ppargc1a Sf1 Sf1 Gna13 Gna13 Pdcd4 Pdcd4 Mef2c Mef2c Apod Apod Trib1 Trib1 Pik3r1 Pik3r1 Aif1 Aif1 Ccdc142 Ccdc142 Ralbp1 Ralbp1 Nos3 Nos3 Gper1 Gper1 Rgs5 Rgs5 Esr2 Esr2 Gna12 Gna12 Cav1 Cav1 Myocd Myocd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Bmp2Bone morphogenetic protein 2. (398 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (106 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
LOC105989276Glutathione S-transferase P; Belongs to the GST superfamily. (210 aa)
Ndrg4Protein NDRG4 isoform X1. (404 aa)
OgnMimecan. (266 aa)
Tnfaip3Tumor necrosis factor alpha-induced protein 3. (329 aa)
Cnn1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
PpargPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
ApoeApolipoprotein E. (274 aa)
ComtCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (267 aa)
Igfbp3Insulin-like growth factor-binding protein 3. (172 aa)
Npr1Guanylate cyclase. (1060 aa)
PtgirProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (382 aa)
AplnApelin. (77 aa)
Il12bInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa)
Ndrg2Protein NDRG2 isoform X1. (371 aa)
Igfbp5Insulin-like growth factor-binding protein 5. (271 aa)
Prkg1cGMP-dependent protein kinase. (686 aa)
PtenPhosphatase and tensin homolog. (396 aa)
PpardPeroxisome proliferator-activated receptor delta isoform X1. (433 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (933 aa)
Efemp2EGF-containing fibulin-like extracellular matrix protein 2. (443 aa)
Il10Interleukin-10. (178 aa)
S1pr2Sphingosine 1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa)
AdipoqAdiponectin. (251 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Npr3Atrial natriuretic peptide receptor 3 isoform X1. (541 aa)
Ace2Angiotensin-converting enzyme. (805 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (285 aa)
VipVIP peptides isoform X1. (170 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (797 aa)
Sf1Splicing factor 1 isoform X4. (642 aa)
Gna13Guanine nucleotide-binding protein subunit alpha-13. (372 aa)
Pdcd4Programmed cell death protein 4 isoform X1. (469 aa)
Mef2cMyocyte-specific enhancer factor 2C isoform X5. (483 aa)
ApodApolipoprotein D. (189 aa)
Trib1Tribbles homolog 1. (141 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Aif1Allograft inflammatory factor 1 isoform X1. (147 aa)
Ccdc142Coiled-coil domain-containing protein 142. (722 aa)
Ralbp1ralA-binding protein 1. (654 aa)
Nos3Nitric oxide synthase; Produces nitric oxide (NO). (1201 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
Rgs5Regulator of G-protein signaling 5. (181 aa)
Esr2Estrogen receptor beta. (550 aa)
Gna12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
MyocdMyocardin. (923 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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