STRINGSTRING
Hoxb7 Hoxb7 Hoxb5 Hoxb5 Hoxb4 Hoxb4 Hoxb3 Hoxb3 Etl4 Etl4 Nodal Nodal Osr2 Osr2 Col11a1 Col11a1 Nkx3-2 Nkx3-2 Pax7 Pax7 Slc35d1 Slc35d1 Sulf2 Sulf2 Flvcr1 Flvcr1 Prrx1 Prrx1 Pcsk5 Pcsk5 Rbp4 Rbp4 Tgfb2 Tgfb2 Ift140 Ift140 Gnas Gnas Hsd17b7 Hsd17b7 Wnt9a Wnt9a Six2 Six2 Tbx15 Tbx15 Wnt11 Wnt11 Irx5 Irx5 Twist2 Twist2 Mbtd1 Mbtd1 Shox2 Shox2 Mthfd1l Mthfd1l Hoxa1 Hoxa1 Hoxa2 Hoxa2 Hoxa6 Hoxa6 Mks1 Mks1 Slc39a3 Slc39a3 Hoxc4 Hoxc4 ENSDORP00000020585 ENSDORP00000020585 Hyal1 Hyal1 Hoxa7 Hoxa7 ENSDORP00000021345 ENSDORP00000021345 Tulp3 Tulp3 Slc2a10 Slc2a10 Wnt5a Wnt5a Hoxd4 Hoxd4 Wdr19 Wdr19 Hoxa3 Hoxa3 Slc39a1 Slc39a1 Pax5 Pax5 Hoxb6 Hoxb6 Hoxc6 Hoxc6 Smad3 Smad3 Nipbl Nipbl Fgf8 Fgf8 Nog Nog Hoxc9 Hoxc9 Rdh10 Rdh10 Dlk1 Dlk1 Hoxb9 Hoxb9 Men1 Men1 Tbx1 Tbx1 Mmp14 Mmp14 Mmp16 Mmp16 Osr1 Osr1 Gli3 Gli3 Dscaml1 Dscaml1 Tapt1 Tapt1 Bmp4 Bmp4 Cdk20 Cdk20 Mycn Mycn Med12 Med12 Dlx6 Dlx6 Hoxd1 Hoxd1 Col2a1 Col2a1 Pbx1 Pbx1 Tfap2a Tfap2a Tbxt Tbxt Tgfb3 Tgfb3 Eif4a3 Eif4a3 Hspg2 Hspg2 Sulf1 Sulf1 Col1a1 Col1a1 Chst11 Chst11 Alx4 Alx4 Setd2 Setd2 Ednra Ednra Acvr2a Acvr2a Tgfbr2 Tgfbr2 Myf5 Myf5 Mdfi Mdfi Deaf1 Deaf1 Pcgf2 Pcgf2 Ndst1 Ndst1 Eya1 Eya1 Sp1 Sp1 Six1 Six1 Fgfr2 Fgfr2 Fuz Fuz Dlx2 Dlx2 Xylt1 Xylt1 Bmi1 Bmi1 Smad2 Smad2 Tgfbr1 Tgfbr1 Mef2c Mef2c Hoxd3 Hoxd3 Hoxa5 Hoxa5 Sp3 Sp3 Gsc Gsc Dlx1 Dlx1 Asxl2 Asxl2 Pdgfra Pdgfra Zeb1 Zeb1 Six4 Six4 Hoxb2 Hoxb2 Hoxb1 Hoxb1 Alx3 Alx3 Runx2 Runx2 Hoxa9 Hoxa9 Hoxa11 Hoxa11 Wnt9b Wnt9b Wdr60 Wdr60 Ucma Ucma Lhx1 Lhx1 Hoxc11 Hoxc11 Hoxc5 Hoxc5 Grhl2 Grhl2 Dmrt2 Dmrt2 Hand2 Hand2 Hoxd10 Hoxd10 Ihh Ihh Megf8 Megf8 Hoxb8 Hoxb8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hoxb7Homeobox protein Hox-B7. (217 aa)
Hoxb5Homeobox protein Hox-B5. (269 aa)
Hoxb4Homeobox protein Hox-B4. (212 aa)
Hoxb3Homeobox protein Hox-B3. (436 aa)
Etl4Sickle tail protein homolog isoform X4. (1343 aa)
NodalNodal homolog. (353 aa)
Osr2Protein odd-skipped-related 2 isoform X1. (312 aa)
Col11a1Collagen alpha-1(XI) chain isoform X2. (1762 aa)
Nkx3-2Homeobox protein Nkx-3.2. (284 aa)
Pax7Paired box protein Pax-7 isoform X1. (505 aa)
Slc35d1UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter. (276 aa)
Sulf2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (876 aa)
Flvcr1Feline leukemia virus subgroup C receptor-related protein 1. (484 aa)
Prrx1Paired mesoderm homeobox protein 1. (132 aa)
Pcsk5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (912 aa)
Rbp4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (239 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (443 aa)
Ift140Intraflagellar transport protein 140 homolog. (1494 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Hsd17b73-keto-steroid reductase isoform X1. (305 aa)
Wnt9aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
Six2Homeobox protein SIX2. (299 aa)
Tbx15T-box transcription factor TBX15. (583 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Irx5Iroquois-class homeodomain protein IRX-5 isoform X1. (513 aa)
Twist2Twist-related protein 2. (160 aa)
Mbtd1MBT domain-containing protein 1 isoform X4. (433 aa)
Shox2Short stature homeobox protein 2 isoform X2. (190 aa)
Mthfd1lMonofunctional C1-tetrahydrofolate synthase, mitochondrial. (831 aa)
Hoxa1Homeobox protein Hox-A1 isoform X1. (338 aa)
Hoxa2Homeobox protein Hox-A2. (374 aa)
Hoxa6Homeobox protein Hox-A6. (233 aa)
Mks1Meckel syndrome type 1 protein. (559 aa)
Slc39a3Zinc transporter ZIP3. (192 aa)
Hoxc4Homeobox protein Hox-C4. (264 aa)
ENSDORP00000020585annotation not available (80 aa)
Hyal1Hyaluronidase. (462 aa)
Hoxa7Homeobox protein Hox-A7. (237 aa)
ENSDORP00000021345annotation not available (171 aa)
Tulp3Tubby-like protein; Belongs to the TUB family. (452 aa)
Slc2a10Solute carrier family 2, facilitated glucose transporter member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (515 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
Hoxd4Homeobox protein Hox-D4. (255 aa)
Wdr19WD repeat-containing protein 19. (1266 aa)
Hoxa3Homeobox protein Hox-A3. (442 aa)
Slc39a1Zinc transporter ZIP1. (324 aa)
Pax5Paired box protein Pax-5 isoform X3. (391 aa)
Hoxb6Homeobox protein Hox-B6. (224 aa)
Hoxc6Homeobox protein Hox-C6 isoform X1. (235 aa)
Smad3Mothers against decapentaplegic homolog. (425 aa)
NipblNipped-B protein. (2804 aa)
Fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
NogNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (233 aa)
Hoxc9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
Rdh10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
Dlk1Protein delta homolog 1. (360 aa)
Hoxb9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
Men1Menin isoform X2. (610 aa)
Tbx1T-box transcription factor TBX1. (254 aa)
Mmp14Matrix metalloproteinase-14. (584 aa)
Mmp16Matrix metalloproteinase-16. (607 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
Gli3Transcriptional activator GLI3. (1508 aa)
Dscaml1Down syndrome cell adhesion molecule-like protein 1. (1967 aa)
Tapt1Transmembrane anterior posterior transformation protein 1 homolog. (501 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
Cdk20Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily. (346 aa)
MycnN-myc proto-oncogene protein. (461 aa)
Med12Mediator of RNA polymerase II transcription subunit 12. (2183 aa)
Dlx6Homeobox protein DLX-6. (147 aa)
Hoxd1Homeobox protein Hox-D1. (330 aa)
Col2a1Collagen alpha-1(II) chain isoform X2. (1487 aa)
Pbx1pre-B-cell leukemia transcription factor 1 isoform X1. (430 aa)
Tfap2aTranscription factor AP-2-alpha isoform X1. (437 aa)
TbxtBrachyury protein isoform X1. (137 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Eif4a3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (419 aa)
Hspg2Basement membrane-specific heparan sulfate proteoglycan core protein. (4318 aa)
Sulf1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (870 aa)
Col1a1Collagen alpha-1(I) chain. (1285 aa)
Chst11Carbohydrate sulfotransferase. (352 aa)
Alx4Homeobox protein aristaless-like 4. (411 aa)
Setd2Histone-lysine N-methyltransferase SETD2. (2320 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
Acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
Myf5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MdfimyoD family inhibitor isoform X1. (245 aa)
Deaf1Deformed epidermal autoregulatory factor 1 homolog. (500 aa)
Pcgf2Polycomb group RING finger protein 2 isoform X2. (344 aa)
Ndst1Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 isoform X1. (882 aa)
Eya1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
Sp1Transcription factor Sp1. (786 aa)
Six1Homeobox protein SIX1. (284 aa)
Fgfr2Fibroblast growth factor receptor. (819 aa)
FuzProtein fuzzy homolog isoform X2. (415 aa)
Dlx2Homeobox protein DLX-2. (333 aa)
Xylt1Xylosyltransferase 1. (911 aa)
Bmi1Polycomb complex protein BMI-1. (324 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (490 aa)
Mef2cMyocyte-specific enhancer factor 2C isoform X5. (483 aa)
Hoxd3Homeobox protein Hox-D3. (433 aa)
Hoxa5Homeobox protein Hox-A5. (270 aa)
Sp3Transcription factor Sp3. (774 aa)
GscHomeobox protein goosecoid. (256 aa)
Dlx1Homeobox protein DLX-1. (255 aa)
Asxl2Putative Polycomb group protein ASXL2. (1387 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
Zeb1Zinc finger E-box-binding homeobox 1 isoform X2. (1105 aa)
Six4Homeobox protein SIX4. (727 aa)
Hoxb2Homeobox protein Hox-B2. (355 aa)
Hoxb1Homeobox protein Hox-B1. (302 aa)
Alx3Homeobox protein aristaless-like 3. (344 aa)
Runx2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (570 aa)
Hoxa9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa)
Hoxa11Homeobox protein Hox-A11 isoform X3. (300 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
Wdr60WD repeat-containing protein 60. (954 aa)
UcmaUnique cartilage matrix-associated protein isoform X1. (138 aa)
Lhx1LIM/homeobox protein Lhx1. (406 aa)
Hoxc11Homeobox protein Hox-C11. (304 aa)
Hoxc5Homeobox protein Hox-C5. (222 aa)
Grhl2Grainyhead-like protein 2 homolog. (631 aa)
Dmrt2Doublesex- and mab-3-related transcription factor 2. (507 aa)
Hand2Heart- and neural crest derivatives-expressed protein 2. (217 aa)
Hoxd10Homeobox protein Hox-D10. (340 aa)
IhhIndian hedgehog protein. (397 aa)
Megf8Multiple epidermal growth factor-like domains protein 8 isoform X2. (2789 aa)
Hoxb8Homeobox protein Hox-B8 isoform X1. (243 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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