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Wnk3 Wnk3 Camk2a Camk2a Drd1 Drd1 LOC106002211 LOC106002211 F2 F2 Ffar1 Ffar1 LOC106001478 LOC106001478 Oga Oga Npsr1 Npsr1 Stac2 Stac2 Nipsnap2 Nipsnap2 Ryr2 Ryr2 Stac Stac Ucn Ucn Trpv3 Trpv3 Dspp Dspp Pdgfrb Pdgfrb R3hdm1-2 R3hdm1-2 Aqp2 Aqp2 Itpr1 Itpr1 Sumo1 Sumo1 Gper1 Gper1 Cask Cask Plp1 Plp1 Ccr1 Ccr1 Aplnr Aplnr Sphk2 Sphk2 LOC105997812 LOC105997812 Lhcgr Lhcgr Orai1 Orai1 Ehd3 Ehd3 Hcrt Hcrt Dbi Dbi Cav1 Cav1 Casq1 Casq1 Jak3 Jak3 G6pd G6pd Cacnb3 Cacnb3 Wfs1 Wfs1 Tspo Tspo Slc9a1 Slc9a1 Plcg1 Plcg1 Pdpk1 Pdpk1 Cd19 Cd19 Bak1 Bak1 Stc1 Stc1 Stim1 Stim1 Adcyap1r1 Adcyap1r1 F2r F2r Grin1 Grin1 Atp2b2 Atp2b2 Arrb2 Arrb2 Thy1 Thy1 Pdgfb Pdgfb Mchr1 Mchr1 Ramp3 Ramp3 Stim2-2 Stim2-2 ENSDORP00000020658 ENSDORP00000020658 Cacna1c Cacna1c S100a1 S100a1 Cacnb4 Cacnb4 Atp2b1 Atp2b1 Cxcl12 Cxcl12 Atp2c2 Atp2c2 Kcne3 Kcne3 ENSDORP00000018748 ENSDORP00000018748 Homer1 Homer1 Snca Snca Trpc4 Trpc4 Stimate Stimate Cldn16 Cldn16 Trpv2 Trpv2 Capn3 Capn3 Cdk5 Cdk5 Ms4a1 Ms4a1 Hap1 Hap1 Rgn Rgn Akap6 Akap6 R3hdm2 R3hdm2 Stac3 Stac3 Serpine1 Serpine1 Bmp4 Bmp4 Trpc6 Trpc6 Pkd2 Pkd2 Il13 Il13 Gpr39 Gpr39 Cacna2d1 Cacna2d1 Cxcl11 Cxcl11 Gcg Gcg Cacnb2 Cacnb2 R3hdm1 R3hdm1 P2rx1 P2rx1 Mylk Mylk Crh Crh P2rx5 P2rx5 Trpc1 Trpc1 Cxcl9 Cxcl9 Ednra Ednra Lpar3 Lpar3 Cx3cl1 Cx3cl1 Bax Bax Atp1b1 Atp1b1 Trpc3 Trpc3 Plcg2 Plcg2 Rapgef3 Rapgef3 Stim2 Stim2 Bdkrb1 Bdkrb1 Vmp1 Vmp1 P2ry6 P2ry6 Sri Sri Cxcr4 Cxcr4 Htt Htt Cxcr3 Cxcr3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Wnk3Serine/threonine-protein kinase WNK3. (1482 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (488 aa)
Drd1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (447 aa)
LOC106002211Small ubiquitin-related modifier. (89 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (619 aa)
Ffar1Free fatty acid receptor 1. (300 aa)
LOC106001478GTPase IMAP family member 5-like. (298 aa)
OgaProtein O-GlcNAcase. (916 aa)
Npsr1Neuropeptide S receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
Stac2SH3 and cysteine-rich domain-containing protein 2. (408 aa)
Nipsnap2Protein NipSnap homolog 2. (277 aa)
Ryr2Ryanodine receptor 2. (4946 aa)
StacSH3 and cysteine-rich domain-containing protein isoform X1. (403 aa)
UcnUrocortin. (130 aa)
Trpv3Transient receptor potential cation channel subfamily V member 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (790 aa)
DsppDentin sialophosphoprotein. (1003 aa)
PdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa)
R3hdm1-2R3H domain-containing protein 1 isoform X6. (287 aa)
Aqp2Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2702 aa)
Sumo1Small ubiquitin-related modifier 1. (83 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
CaskPeripheral plasma membrane protein CASK isoform X1; Belongs to the MAGUK family. (927 aa)
Plp1Myelin proteolipid protein. (242 aa)
Ccr1C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (344 aa)
AplnrApelin receptor; Belongs to the G-protein coupled receptor 1 family. (379 aa)
Sphk2Sphingosine kinase 2. (619 aa)
LOC105997812LOW QUALITY PROTEIN: uncharacterized protein LOC105997812. (91 aa)
LhcgrLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (692 aa)
Orai1Calcium release-activated calcium channel protein 1. (300 aa)
Ehd3EH domain-containing protein 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
HcrtOrexin. (131 aa)
Dbiacyl-CoA-binding protein. (79 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
Casq1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (408 aa)
Jak3Tyrosine-protein kinase JAK3. (999 aa)
G6pdGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (535 aa)
Cacnb3Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (485 aa)
Wfs1Wolframin. (885 aa)
TspoTranslocator protein. (168 aa)
Slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (802 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Pdpk13-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
Cd19B-lymphocyte antigen CD19. (538 aa)
Bak1Bcl-2 homologous antagonist/killer. (211 aa)
Stc1Stanniocalcin-1. (247 aa)
Stim1Stromal interaction molecule 1 isoform X2. (685 aa)
Adcyap1r1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (610 aa)
F2rProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (428 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
Atp2b2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
Arrb2Beta-arrestin-2 isoform X1. (420 aa)
Thy1Thy-1 membrane glycoprotein. (161 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
Mchr1Melanin-concentrating hormone receptor 1. (311 aa)
Ramp3Receptor activity-modifying protein 3. (147 aa)
Stim2-2Stromal interaction molecule 2. (85 aa)
ENSDORP00000020658annotation not available (108 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
S100a1Protein S100; Belongs to the S-100 family. (94 aa)
Cacnb4Voltage-dependent L-type calcium channel subunit beta-4. (333 aa)
Atp2b1Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1019 aa)
Cxcl12Stromal cell-derived factor 1 isoform X2; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
Atp2c2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (952 aa)
Kcne3Potassium voltage-gated channel subfamily E member 3. (107 aa)
ENSDORP00000018748annotation not available (67 aa)
Homer1Homer protein homolog 1. (361 aa)
SncaAlpha-synuclein; Belongs to the synuclein family. (140 aa)
Trpc4Short transient receptor potential channel 4 isoform X2; Belongs to the transient receptor (TC 1.A.4) family. (978 aa)
StimateTransmembrane protein 110-like. (276 aa)
Cldn16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (289 aa)
Trpv2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (753 aa)
Capn3Calpain-3 isoform X2; Belongs to the peptidase C2 family. (815 aa)
Cdk5Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
Ms4a1B-lymphocyte antigen CD20 isoform X1. (298 aa)
Hap1Huntingtin-associated protein 1. (580 aa)
RgnRegucalcin. (300 aa)
Akap6A-kinase anchor protein 6. (2320 aa)
R3hdm2R3H domain-containing protein 2. (930 aa)
Stac3SH3 and cysteine-rich domain-containing protein 3 isoform X1. (359 aa)
Serpine1Plasminogen activator inhibitor 1 isoform X2; Belongs to the serpin family. (401 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
Trpc6Short transient receptor potential channel 6. (513 aa)
Pkd2Polycystin-2. (968 aa)
Il13Interleukin-13 isoform X2. (127 aa)
Gpr39G-protein coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (447 aa)
Cacna2d1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1079 aa)
Cxcl11C-X-C motif chemokine. (91 aa)
GcgGlucagon isoform X1. (180 aa)
Cacnb2Voltage-dependent L-type calcium channel subunit beta-2 isoform X2. (580 aa)
R3hdm1R3H domain-containing protein 1 isoform X2. (384 aa)
P2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
MylkMyosin light chain kinase, smooth muscle isoform X2. (1904 aa)
CrhCorticoliberin. (188 aa)
P2rx5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (233 aa)
Trpc1Short transient receptor potential channel 1. (756 aa)
Cxcl9C-X-C motif chemokine. (124 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
Lpar3Lysophosphatidic acid receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
Cx3cl1Fractalkine. (385 aa)
BaxApoptosis regulator BAX. (143 aa)
Atp1b1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (293 aa)
Trpc3Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (836 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
Rapgef3Rap guanine nucleotide exchange factor 3. (216 aa)
Stim2Stromal interaction molecule 2. (566 aa)
Bdkrb1B1 bradykinin receptor. (326 aa)
Vmp1Vacuole membrane protein 1. (410 aa)
P2ry6p2Y purinoceptor 6 isoform X3. (327 aa)
SriSorcin. (198 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (357 aa)
HttHuntingtin. (3048 aa)
Cxcr3C-X-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (366 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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