STRINGSTRING
Nrxn1 Nrxn1 Aph1b Aph1b Drd3 Drd3 Chd8 Chd8 Fabp7 Fabp7 Nlgn3 Nlgn3 Grin3a Grin3a Grid2 Grid2 Dbn1 Dbn1 Pten Pten Drd2 Drd2 Slc6a3 Slc6a3 Grin1 Grin1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Nrxn1Neurexin-1-beta isoform X1. (1515 aa)
Aph1bGamma-secretase subunit APH-1B. (257 aa)
Drd3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (445 aa)
Chd8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2478 aa)
Fabp7Fatty acid-binding protein, brain; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
Nlgn3Neuroligin-3 isoform X1. (848 aa)
Grin3aGlutamate receptor ionotropic, NMDA 3A isoform X1. (1134 aa)
Grid2Glutamate receptor ionotropic, delta-2 isoform X1. (977 aa)
Dbn1Drebrin. (169 aa)
PtenPhosphatase and tensin homolog. (396 aa)
Drd2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
Slc6a3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (635 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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