STRINGSTRING
Cd2ap Cd2ap Pibf1 Pibf1 Fgf20 Fgf20 Sdcbp Sdcbp Ms4a1 Ms4a1 Klb Klb Il21 Il21 Trip6 Trip6 Slc9a3r1 Slc9a3r1 Grap Grap Myd88 Myd88 Nptn Nptn Areg Areg Flrt2 Flrt2 Fgf22 Fgf22 Rnf126 Rnf126 Shc1 Shc1 Pdgfa Pdgfa Snx1 Snx1 Ncstn Ncstn Yes1 Yes1 Pspn Pspn ENSDORP00000002242 ENSDORP00000002242 Vav3 Vav3 Csf2 Csf2 Pigr Pigr Psen1 Psen1 Vegfb Vegfb Ern1 Ern1 Il6st Il6st Rasa1 Rasa1 Cadm4 Cadm4 Fgf21 Fgf21 Lyn Lyn Egf Egf Irak1 Irak1 Frs2 Frs2 Fgf1 Fgf1 Fgf7 Fgf7 Il1a Il1a Efemp1 Efemp1 Tollip Tollip Itgb3 Itgb3 Ms4a4a Ms4a4a Src Src Btc Btc Il5 Il5 Csf3 Csf3 Snx2 Snx2 Irak4 Irak4 Il2 Il2 Il6r Il6r 1700057G04Rik 1700057G04Rik Adam17 Adam17 Pdgfd Pdgfd Epgn Epgn Fgf5 Fgf5 Erbb4 Erbb4 Il36a Il36a Rnf41 Rnf41 Tlr9 Tlr9 Il11 Il11 Grb2 Grb2 Fgf16 Fgf16 Atxn2 Atxn2 Il7 Il7 Lingo2 Lingo2 Tlr5 Tlr5 LOC105989822 LOC105989822 Fgf4 Fgf4 Il1r1 Il1r1 Cntf Cntf LOC106002438 LOC106002438 Grem1 Grem1 Ptprj Ptprj Il1f5 Il1f5 Ms4a15 Ms4a15 Agr2 Agr2 Pdgfrb Pdgfrb Glmn Glmn Fgf8 Fgf8 Ecm1 Ecm1 Il1rap Il1rap Dab2ip Dab2ip Pycard Pycard Il1f10 Il1f10 Fgf18 Fgf18 Cystm1 Cystm1 Pgf Pgf Esm1 Esm1 Fgf9 Fgf9 Tgfa Tgfa Pdgfb Pdgfb Gata3 Gata3 Cnot9 Cnot9 Kl Kl Snx4 Snx4 Socs5 Socs5 Pik3r1 Pik3r1 Lingo1 Lingo1 Pdgfra Pdgfra Arf4 Arf4 Il1rn Il1rn Jak2 Jak2 Flrt1 Flrt1 Vegfc Vegfc Gdnf Gdnf Fgf2 Fgf2 Tnk2 Tnk2 Nrxn1 Nrxn1 Fgf6 Fgf6 Hbegf Hbegf Pdcl3 Pdcl3 Fgf17 Fgf17 Fer Fer Vav2 Vav2 Ccdc88a Ccdc88a Pdgfc Pdgfc Il1b Il1b Pdcl2 Pdcl2 Flrt3 Flrt3 Pten Pten Ereg Ereg Itga5 Itga5 Vegfd Vegfd Fgf10 Fgf10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cd2apCD2-associated protein. (634 aa)
Pibf1Progesterone-induced-blocking factor 1. (771 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
SdcbpSyntenin-1. (244 aa)
Ms4a1B-lymphocyte antigen CD20 isoform X1. (298 aa)
KlbBeta-klotho. (976 aa)
Il21Interleukin; Belongs to the IL-15/IL-21 family. (156 aa)
Trip6Thyroid receptor-interacting protein 6 isoform X1. (482 aa)
Slc9a3r1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (359 aa)
GrapGRB2-related adapter protein isoform X1. (217 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (338 aa)
NptnNeuroplastin. (397 aa)
AregAmphiregulin. (245 aa)
Flrt2Leucine-rich repeat transmembrane protein FLRT2. (660 aa)
Fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
Rnf126E3 ubiquitin-protein ligase RNF126. (310 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
PdgfaPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (210 aa)
Snx1Sorting nexin-1. (304 aa)
NcstnNicastrin. (698 aa)
Yes1Tyrosine-protein kinase. (541 aa)
PspnPersephin. (159 aa)
ENSDORP00000002242annotation not available (278 aa)
Vav3Guanine nucleotide exchange factor VAV3. (847 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (140 aa)
PigrPolymeric immunoglobulin receptor. (766 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
VegfbVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (204 aa)
Ern1Serine/threonine-protein kinase/endoribonuclease IRE1. (406 aa)
Il6stInterleukin-6 receptor subunit beta. (828 aa)
Rasa1Ras GTPase-activating protein 1. (813 aa)
Cadm4Cell adhesion molecule 4. (380 aa)
Fgf21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa)
LynTyrosine-protein kinase. (512 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (664 aa)
Irak1Interleukin-1 receptor-associated kinase 1. (714 aa)
Frs2Fibroblast growth factor receptor substrate 2. (507 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Il1aInterleukin-1; Belongs to the IL-1 family. (270 aa)
Efemp1EGF-containing fibulin-like extracellular matrix protein 1 isoform X2. (494 aa)
TollipToll-interacting protein. (263 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (766 aa)
Ms4a4aMembrane-spanning 4-domains subfamily A member 4A-like isoform X1. (226 aa)
SrcTyrosine-protein kinase. (539 aa)
BtcProbetacellulin. (163 aa)
Il5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
Csf3Granulocyte colony-stimulating factor isoform X2. (205 aa)
Snx2Sorting nexin-2. (506 aa)
Irak4Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa)
Il2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
Il6rInterleukin-6 receptor subunit alpha. (445 aa)
1700057G04RikPhospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (163 aa)
Adam17Disintegrin and metalloproteinase domain-containing protein 17. (834 aa)
PdgfdPlatelet-derived growth factor D. (256 aa)
EpgnEpigen isoform X5. (153 aa)
Fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (272 aa)
Erbb4Receptor protein-tyrosine kinase. (1308 aa)
Il36aInterleukin-1. (158 aa)
Rnf41E3 ubiquitin-protein ligase NRDP1. (317 aa)
Tlr9Toll-like receptor 9 isoform X3. (1029 aa)
Il11Interleukin-11. (197 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
Atxn2Ataxin-2. (1047 aa)
Il7Interleukin-7 isoform X1. (156 aa)
Lingo2Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2. (606 aa)
Tlr5Toll-like receptor 5; Belongs to the Toll-like receptor family. (878 aa)
LOC105989822Aminopeptidase. (942 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (52 aa)
Il1r1Interleukin-1 receptor type 1 isoform X1. (574 aa)
CntfCiliary neurotrophic factor. (197 aa)
LOC106002438Interleukin-6 receptor subunit beta-like. (123 aa)
Grem1Gremlin. (184 aa)
PtprjReceptor-type tyrosine-protein phosphatase eta. (1205 aa)
Il1f5Interleukin-1. (162 aa)
Ms4a15Membrane-spanning 4-domains subfamily A member 15. (245 aa)
Agr2Anterior gradient protein 2 homolog. (192 aa)
PdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa)
GlmnGlomulin. (595 aa)
Fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
Ecm1Extracellular matrix protein 1 isoform X1. (546 aa)
Il1rapInterleukin-1 receptor accessory protein isoform X1. (665 aa)
Dab2ipDisabled homolog 2-interacting protein isoform X1. (1166 aa)
PycardApoptosis-associated speck-like protein containing a CARD. (190 aa)
Il1f10Interleukin-1. (152 aa)
Fgf18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (185 aa)
Cystm1Cysteine-rich and transmembrane domain-containing protein 1. (101 aa)
PgfPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (159 aa)
Esm1Endothelial cell-specific molecule 1. (184 aa)
Fgf9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TgfaProtransforming growth factor alpha. (156 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
Cnot9Cell differentiation protein RCD1 homolog isoform X1. (299 aa)
KlKlotho. (1020 aa)
Snx4Sorting nexin 4. (392 aa)
Socs5Suppressor of cytokine signaling 5. (536 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Lingo1Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1. (617 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
Arf4ADP-ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (180 aa)
Il1rnInterleukin-1. (177 aa)
Jak2Tyrosine-protein kinase. (1037 aa)
Flrt1Leucine-rich repeat transmembrane protein FLRT1. (674 aa)
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
GdnfGlial cell line-derived neurotrophic factor isoform X1. (240 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
Tnk2Activated CDC42 kinase 1. (976 aa)
Nrxn1Neurexin-1-beta isoform X1. (1515 aa)
Fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (146 aa)
HbegfProheparin-binding EGF-like growth factor. (206 aa)
Pdcl3Phosducin-like protein 3. (240 aa)
Fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FerTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (775 aa)
Vav2Guanine nucleotide exchange factor VAV2. (766 aa)
Ccdc88aGirdin. (1835 aa)
PdgfcPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (344 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Pdcl2Uncharacterized protein LOC105980190. (241 aa)
Flrt3Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
PtenPhosphatase and tensin homolog. (396 aa)
EregProepiregulin. (163 aa)
Itga5Integrin alpha-5; Belongs to the integrin alpha chain family. (1057 aa)
VegfdVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (351 aa)
Fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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