STRINGSTRING
Scn7a Scn7a Kcnh2 Kcnh2 Cacna2d1 Cacna2d1 Cacnb2 Cacnb2 Scn10a Scn10a Scn1a Scn1a Scn3b Scn3b Cacna1i Cacna1i Cacna1g Cacna1g Scn4a Scn4a Hcn4 Hcn4 Scn9a Scn9a Scn2b Scn2b Scn8a Scn8a Scn11a Scn11a ENSDORP00000016518 ENSDORP00000016518 Ywhah Ywhah Scn1b Scn1b Scn5a Scn5a Cacna1c Cacna1c Cacna1h Cacna1h ENSDORP00000023335 ENSDORP00000023335 Scn4b Scn4b Scn3a Scn3a Trpm4 Trpm4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Scn7aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1636 aa)
Kcnh2Potassium voltage-gated channel subfamily H member 2. (1141 aa)
Cacna2d1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1079 aa)
Cacnb2Voltage-dependent L-type calcium channel subunit beta-2 isoform X2. (580 aa)
Scn10aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1937 aa)
Scn1aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1998 aa)
Scn3bSodium channel subunit beta-3. (175 aa)
Cacna1iVoltage-dependent T-type calcium channel subunit alpha-1I. (2201 aa)
Cacna1gVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2385 aa)
Scn4aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1825 aa)
Hcn4Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4. (712 aa)
Scn9aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
Scn2bSodium channel subunit beta-2. (215 aa)
Scn8aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1982 aa)
Scn11aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1620 aa)
ENSDORP00000016518annotation not available (92 aa)
Ywhah14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
Scn1bSodium channel subunit beta-1. (216 aa)
Scn5aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1926 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
Cacna1hVoltage-dependent T-type calcium channel subunit alpha-1H. (2166 aa)
ENSDORP00000023335annotation not available (456 aa)
Scn4bSodium channel subunit beta-4. (229 aa)
Scn3aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1985 aa)
Trpm4Transient receptor potential cation channel subfamily M member 4. (1206 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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