STRINGSTRING
Ppp1r10 Ppp1r10 Rad17 Rad17 Ndc80 Ndc80 Mad2l1 Mad2l1 Cenpn Cenpn Gar1 Gar1 ENSDORP00000000668 ENSDORP00000000668 Cenpa Cenpa Rbbp7 Rbbp7 Ercc4 Ercc4 Chmp4a Chmp4a Mdp1 Mdp1 Plk1 Plk1 Zbtb10 Zbtb10 Macroh2a1 Macroh2a1 Cdca8 Cdca8 Psen2 Psen2 Psen1 Psen1 H2ax H2ax Chmp4c Chmp4c Upf1 Upf1 Chek1 Chek1 Zwint Zwint Rangap1 Rangap1 Ppp2r5c Ppp2r5c Rad51ap1 Rad51ap1 Rad51 Rad51 ENSDORP00000027329 ENSDORP00000027329 Dhx36 Dhx36 Men1 Men1 Lage3 Lage3 Xpo1 Xpo1 Chmp1b Chmp1b Dync1li1 Dync1li1 Suv39h1 Suv39h1 LOC105997002 LOC105997002 Rad51d Rad51d LOC105994671 LOC105994671 ENSDORP00000025740 ENSDORP00000025740 Meaf6 Meaf6 Wdhd1 Wdhd1 Snai1 Snai1 Dynlt3 Dynlt3 Cenpv Cenpv Lrif1 Lrif1 LOC106000013 LOC106000013 Ctcf Ctcf Smc5 Smc5 ENSDORP00000024608 ENSDORP00000024608 Fam193a Fam193a Terf1 Terf1 Cenpo Cenpo LOC105996929 LOC105996929 Kdm4b Kdm4b Bod1l Bod1l Znf207 Znf207 ENSDORP00000023834 ENSDORP00000023834 ENSDORP00000023747 ENSDORP00000023747 H2bc18 H2bc18 Kmt5c Kmt5c Fbxo28 Fbxo28 Crx Crx LOC106002028 LOC106002028 Smc3 Smc3 LOC105997857 LOC105997857 Chmp1a Chmp1a ENSDORP00000023068 ENSDORP00000023068 ENSDORP00000022892 ENSDORP00000022892 Cenpx Cenpx Chmp2a Chmp2a Sgol1 Sgol1 Crebbp Crebbp Nabp1 Nabp1 Rtel1 Rtel1 Rnf8 Rnf8 LOC106000017 LOC106000017 Zfp618 Zfp618 Zw10 Zw10 Pmf1 Pmf1 ENSDORP00000021537 ENSDORP00000021537 LOC105998920 LOC105998920 Slx4 Slx4 LOC105987649 LOC105987649 Ezh2 Ezh2 Ten1 Ten1 Pafah1b1 Pafah1b1 Spc24 Spc24 Pif1 Pif1 Chd4 Chd4 ENSDORP00000020889 ENSDORP00000020889 LOC105993205 LOC105993205 Dctn1 Dctn1 Cenpf Cenpf LOC105997103 LOC105997103 Ppp2ca Ppp2ca Chrac1 Chrac1 Hsf1 Hsf1 Hnrnpa2b1 Hnrnpa2b1 LOC105999998 LOC105999998 Anapc16 Anapc16 Dync1li2 Dync1li2 Champ1 Champ1 Chmp6 Chmp6 Cenpk Cenpk Kdm1a Kdm1a Cenps Cenps ENSDORP00000019608 ENSDORP00000019608 Nek2 Nek2 ENSDORP00000019408 ENSDORP00000019408 LOC105997053 LOC105997053 Rassf4 Rassf4 Nsl1 Nsl1 Atrx Atrx LOC105984045 LOC105984045 Uhrf2 Uhrf2 Smchd1 Smchd1 LOC105992280 LOC105992280 Ss18l1 Ss18l1 Sun2 Sun2 Tex14 Tex14 LOC105992280-2 LOC105992280-2 Rbbp4 Rbbp4 Cenpl Cenpl Pbrm1 Pbrm1 Spout1 Spout1 Smc4 Smc4 ENSDORP00000016493 ENSDORP00000016493 ENSDORP00000016447 ENSDORP00000016447 Apc Apc Cdt1 Cdt1 Cbx1 Cbx1 LOC106002433 LOC106002433 Rskr Rskr Ezh1 Ezh1 Zwilch Zwilch Wdr82 Wdr82 Kntc1 Kntc1 Top2a Top2a Chmp2b Chmp2b Ncapd2 Ncapd2 Kif2c Kif2c Xrcc4 Xrcc4 Dmc1 Dmc1 Nup98 Nup98 Hnrnpu Hnrnpu Kmt5b Kmt5b ENSDORP00000014082 ENSDORP00000014082 Esco2 Esco2 Kat7 Kat7 Bub1 Bub1 Ppp2r1a Ppp2r1a Dot1l Dot1l Rassf2 Rassf2 LOC106000651 LOC106000651 Pold1 Pold1 Thoc3 Thoc3 Dclre1b Dclre1b Daxx Daxx Ska1 Ska1 Atm Atm Ccdc155 Ccdc155 Gatad2b Gatad2b Mtbp Mtbp Hdac2 Hdac2 Ncapg Ncapg Dync1i1 Dync1i1 Nabp2 Nabp2 Ncapd3 Ncapd3 Kat5 Kat5 Baz1b Baz1b Fmr1 Fmr1 Ppp1ca Ppp1ca Phf2 Phf2 Znf276 Znf276 Nde1 Nde1 Csnk1a1 Csnk1a1 Hells Hells Majin Majin Tnks Tnks Trp53bp1 Trp53bp1 Chmp4b Chmp4b Xrcc5 Xrcc5 Ckap5 Ckap5 Ttk Ttk Kdm4a Kdm4a Terf2 Terf2 Dscc1 Dscc1 Ctc1 Ctc1 Blm Blm Kif18a Kif18a Sin3a Sin3a Ska2 Ska2 Smc6 Smc6 Cbx5 Cbx5 Knl1 Knl1 Terb2 Terb2 Fen1 Fen1 Nup43 Nup43 Tox4 Tox4 Gpatch11 Gpatch11 Sycp2l Sycp2l Cenpe Cenpe Recql4 Recql4 Clasp2 Clasp2 Cenpi Cenpi Tep1 Tep1 Cenpu Cenpu Wrn Wrn Nup37 Nup37 Chmp3 Chmp3 Bub3 Bub3 Kat8 Kat8 Nuf2 Nuf2 Ppp1cc Ppp1cc Ikzf1 Ikzf1 Smc1b Smc1b Hat1 Hat1 Spag5 Spag5 Zfp330 Zfp330 Nsmce1 Nsmce1 Polr2b Polr2b ENSDORP00000009450 ENSDORP00000009450 Incenp Incenp Fbxw11 Fbxw11 Zbtb48 Zbtb48 Aurkb Aurkb Nsmce2 Nsmce2 Pml Pml Chek2 Chek2 Dna2 Dna2 Baz1a Baz1a Wrap53 Wrap53 Dctn4 Dctn4 Zfp827 Zfp827 Ercc1 Ercc1 Ppp2cb Ppp2cb Ercc6l Ercc6l Cenpw Cenpw Bub1b Bub1b Orc2 Orc2 Chmp7 Chmp7 Dctn2 Dctn2 Mad1l1 Mad1l1 Dsn1 Dsn1 Cfdp1 Cfdp1 Spdl1 Spdl1 Chmp5 Chmp5 Tfip11 Tfip11 Cenpc Cenpc Xrcc1 Xrcc1 Nup133 Nup133 Stn1 Stn1 Lrwd1 Lrwd1 Cenph Cenph Knstrn Knstrn Seh1l Seh1l Cbx3 Cbx3 Ska3 Ska3 Spc25 Spc25 Rad21 Rad21 Nup107 Nup107 Nup85 Nup85 Rcc2 Rcc2 Ndel1 Ndel1 Mre11 Mre11 Clasp1 Clasp1 Tpr Tpr Terf2ip Terf2ip Pot1 Pot1 Smc1a Smc1a Suv39h2 Suv39h2 Cenpp Cenpp Birc5 Birc5 Nup160 Nup160 Pinx1 Pinx1 Mta2 Mta2 Wrnip1 Wrnip1 Nsmce4a Nsmce4a Cenpb Cenpb Spo11 Spo11 Rpa2 Rpa2 Trappc12 Trappc12 Smarca5 Smarca5 Sirt6 Sirt6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Ppp1r10Serine/threonine-protein phosphatase 1 regulatory subunit 10. (910 aa)
Rad17Cell cycle checkpoint protein RAD17. (640 aa)
Ndc80Kinetochore protein NDC80 homolog. (642 aa)
Mad2l1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
CenpnCentromere protein N. (333 aa)
Gar1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (217 aa)
ENSDORP00000000668annotation not available (111 aa)
CenpaHistone H3-like centromeric protein A isoform X1. (133 aa)
Rbbp7Histone-binding protein RBBP7. (416 aa)
Ercc4DNA repair endonuclease XPF. (784 aa)
Chmp4aCharged multivesicular body protein 4a. (215 aa)
Mdp1Magnesium-dependent phosphatase 1. (164 aa)
Plk1Serine/threonine-protein kinase PLK. (580 aa)
Zbtb10Zinc finger and BTB domain-containing protein 10. (873 aa)
Macroh2a1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
Cdca8Borealin. (278 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
H2axHistone H2A; Belongs to the histone H2A family. (143 aa)
Chmp4cCharged multivesicular body protein 4c. (234 aa)
Upf1Regulator of nonsense transcripts 1. (1106 aa)
Chek1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
ZwintZW10 interactor. (224 aa)
Rangap1Ran GTPase-activating protein 1. (556 aa)
Ppp2r5cSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
Rad51ap1RAD51-associated protein 1. (314 aa)
Rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
ENSDORP00000027329annotation not available (278 aa)
Dhx36ATP-dependent RNA helicase DHX36 isoform X1. (981 aa)
Men1Menin isoform X2. (610 aa)
Lage3EKC/KEOPS complex subunit LAGE3. (150 aa)
Xpo1Exportin-1. (921 aa)
Chmp1bCharged multivesicular body protein 1b. (199 aa)
Dync1li1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (520 aa)
Suv39h1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (401 aa)
LOC105997002Histone H3.1-like. (103 aa)
Rad51dDNA repair protein RAD51 homolog 4. (329 aa)
LOC105994671Chromobox protein homolog 3. (173 aa)
ENSDORP00000025740annotation not available (331 aa)
Meaf6Chromatin modification-related protein MEAF6 isoform X2. (206 aa)
Wdhd1WD repeat and HMG-box DNA-binding protein 1. (952 aa)
Snai1Zinc finger protein SNAI1. (240 aa)
Dynlt3Dynein light chain Tctex-type 3. (114 aa)
CenpvCentromere protein V. (268 aa)
Lrif1Ligand-dependent nuclear receptor-interacting factor 1 isoform X1. (723 aa)
LOC106000013Histone H4-like. (103 aa)
CtcfTranscriptional repressor CTCF. (715 aa)
Smc5Structural maintenance of chromosomes protein 5. (1037 aa)
ENSDORP00000024608annotation not available (540 aa)
Fam193aProtein FAM193A. (1356 aa)
Terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (388 aa)
CenpoCentromere protein O. (292 aa)
LOC105996929Uncharacterized LOC105996929. (103 aa)
Kdm4bLysine-specific demethylase 4B isoform X1. (1082 aa)
Bod1lBiorientation of chromosomes in cell division protein 1-like 1. (2764 aa)
Znf207BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform X1. (494 aa)
ENSDORP00000023834annotation not available (182 aa)
ENSDORP00000023747annotation not available (363 aa)
H2bc18Histone H2B; Belongs to the histone H2B family. (126 aa)
Kmt5cHistone-lysine N-methyltransferase SUV420H2. (466 aa)
Fbxo28F-box only protein 28. (366 aa)
CrxCone-rod homeobox protein. (246 aa)
LOC106002028Histone-lysine N-methyltransferase EZH1-like. (139 aa)
Smc3Structural maintenance of chromosomes protein. (666 aa)
LOC105997857Casein kinase I isoform alpha-like isoform X2; Belongs to the protein kinase superfamily. (336 aa)
Chmp1aCharged multivesicular body protein 1a. (196 aa)
ENSDORP00000023068annotation not available (544 aa)
ENSDORP00000022892annotation not available (166 aa)
CenpxCentromere protein X isoform X2. (69 aa)
Chmp2aCharged multivesicular body protein 2a. (222 aa)
Sgol1Shugoshin-like 1. (84 aa)
CrebbpCREB-binding protein. (2432 aa)
Nabp1SOSS complex subunit B2 isoform X1. (200 aa)
Rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1171 aa)
Rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (81 aa)
LOC106000017Histone H3.1-like. (103 aa)
Zfp618Zinc finger protein 618. (945 aa)
Zw10Centromere/kinetochore protein zw10 homolog. (749 aa)
Pmf1Polyamine-modulated factor 1-like. (201 aa)
ENSDORP00000021537annotation not available (86 aa)
LOC105998920DNA repair protein RAD50-like. (122 aa)
Slx4Structure-specific endonuclease subunit SLX4. (1541 aa)
LOC105987649Spindle and kinetochore-associated protein 2. (95 aa)
Ezh2Histone-lysine N-methyltransferase EZH2 isoform X1. (746 aa)
Ten1CST complex subunit TEN1. (122 aa)
Pafah1b1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
Spc24Kinetochore protein Spc24. (199 aa)
Pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (551 aa)
Chd4chromodomain-helicase-DNA-binding protein 4 isoform X2. (1942 aa)
ENSDORP00000020889annotation not available (51 aa)
LOC105993205Casein kinase I isoform alpha isoform X5. (325 aa)
Dctn1Dynactin subunit 1 isoform X1. (1281 aa)
CenpfCentromere protein F. (2979 aa)
LOC105997103Serine/threonine-protein phosphatase PP1-alpha catalytic subunit pseudogene. (308 aa)
Ppp2caSerine/threonine-protein phosphatase. (309 aa)
Chrac1Chromatin accessibility complex protein 1. (129 aa)
Hsf1Heat shock factor protein 1. (512 aa)
Hnrnpa2b1Heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1. (353 aa)
LOC105999998Uncharacterized LOC105999998. (103 aa)
Anapc16Anaphase-promoting complex subunit 16. (80 aa)
Dync1li2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (432 aa)
Champ1Chromosome alignment-maintaining phosphoprotein 1. (788 aa)
Chmp6Charged multivesicular body protein 6. (37 aa)
CenpkCentromere protein K. (240 aa)
Kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (755 aa)
CenpsCentromere protein S-like. (135 aa)
ENSDORP00000019608annotation not available (164 aa)
Nek2Serine/threonine-protein kinase Nek2. (391 aa)
ENSDORP00000019408annotation not available (108 aa)
LOC105997053Histone H4. (103 aa)
Rassf4Ras association domain-containing protein 4. (321 aa)
Nsl1Kinetochore-associated protein NSL1 homolog. (281 aa)
AtrxTranscriptional regulator ATRX isoform X1. (2472 aa)
LOC105984045TOX high mobility group box family member 4-like. (550 aa)
Uhrf2E3 ubiquitin-protein ligase UHRF2. (767 aa)
Smchd1Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (1911 aa)
LOC105992280Histone H4. (103 aa)
Ss18l1Calcium-responsive transactivator. (377 aa)
Sun2SUN domain-containing protein 2 isoform X1. (721 aa)
Tex14Inactive serine/threonine-protein kinase TEX14. (106 aa)
LOC105992280-2Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
Rbbp4Histone-binding protein RBBP4. (425 aa)
CenplCentromere protein L isoform X1. (346 aa)
Pbrm1Protein polybromo-1 isoform X1. (1704 aa)
Spout1Putative methyltransferase C9orf114 homolog isoform X1. (388 aa)
Smc4Structural maintenance of chromosomes protein. (1279 aa)
ENSDORP00000016493annotation not available (144 aa)
ENSDORP00000016447annotation not available (183 aa)
ApcAdenomatous polyposis coli protein isoform X2. (2842 aa)
Cdt1DNA replication factor Cdt1. (386 aa)
Cbx1Chromobox protein homolog 1 isoform X2. (185 aa)
LOC1060024335' exonuclease Apollo-like. (209 aa)
RskrUncharacterized serine/threonine-protein kinase SgK494 isoform X1. (264 aa)
Ezh1Histone-lysine N-methyltransferase EZH1 isoform X2. (641 aa)
ZwilchZwilch kinetochore protein. (406 aa)
Wdr82WD repeat-containing protein 82. (289 aa)
Kntc1Kinetochore-associated protein 1. (2180 aa)
Top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1510 aa)
Chmp2bCharged multivesicular body protein 2b. (213 aa)
Ncapd2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1370 aa)
Kif2cKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (707 aa)
Xrcc4DNA repair protein XRCC4. (328 aa)
Dmc1LOW QUALITY PROTEIN: meiotic recombination protein DMC1/LIM15 homolog; Belongs to the RecA family. (325 aa)
Nup98Nuclear pore complex protein Nup98-Nup96 isoform X1. (1816 aa)
HnrnpuLOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein U. (787 aa)
Kmt5bHistone-lysine N-methyltransferase SUV420H1 isoform X1. (393 aa)
ENSDORP00000014082annotation not available (135 aa)
Esco2N-acetyltransferase ESCO2. (498 aa)
Kat7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (601 aa)
Bub1Mitotic checkpoint serine/threonine-protein kinase BUB1. (934 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
Dot1lHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1487 aa)
Rassf2Ras association domain-containing protein 2. (322 aa)
LOC106000651Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (423 aa)
Pold1DNA polymerase. (1120 aa)
Thoc3THO complex subunit 3. (294 aa)
Dclre1b5' exonuclease Apollo. (353 aa)
DaxxDeath domain-associated protein 6 isoform X1. (745 aa)
Ska1Spindle and kinetochore-associated protein 1 isoform X1. (104 aa)
AtmSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa)
Ccdc155Protein KASH5. (513 aa)
Gatad2bTranscriptional repressor p66-beta isoform X1. (593 aa)
MtbpMdm2-binding protein isoform X1. (903 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
NcapgCondensin complex subunit 3 isoform X2. (1013 aa)
Dync1i1Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (645 aa)
Nabp2Nucleic acid binding protein 2. (182 aa)
Ncapd3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1480 aa)
Kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
Baz1bTyrosine-protein kinase BAZ1B. (1476 aa)
Fmr1Fragile X mental retardation protein 1 isoform X1. (616 aa)
Ppp1caSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
Phf2Lysine-specific demethylase PHF2. (1064 aa)
Znf276Zinc finger protein 276 isoform X1. (357 aa)
Nde1Nuclear distribution protein nudE homolog 1. (331 aa)
Csnk1a1Casein kinase I isoform alpha isoform X1. (275 aa)
HellsLymphoid-specific helicase. (837 aa)
MajinUncharacterized protein C11orf85 homolog. (222 aa)
TnksTankyrase-1. (1239 aa)
Trp53bp1Tumor suppressor p53-binding protein 1 isoform X1. (1969 aa)
Chmp4bCharged multivesicular body protein 4b. (224 aa)
Xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (692 aa)
Ckap5Cytoskeleton-associated protein 5. (2000 aa)
TtkDual specificity protein kinase TTK isoform X2. (849 aa)
Kdm4aLysine-specific demethylase 4A. (1012 aa)
Terf2Telomeric repeat-binding factor 2 isoform X1. (544 aa)
Dscc1Sister chromatid cohesion protein DCC1. (348 aa)
Ctc1CST complex subunit CTC1. (1181 aa)
BlmBloom syndrome protein isoform X1. (1034 aa)
Kif18aKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (893 aa)
Sin3aPaired amphipathic helix protein Sin3a. (1274 aa)
Ska2Spindle and kinetochore-associated protein 2. (99 aa)
Smc6Structural maintenance of chromosomes protein 6 isoform X1. (1097 aa)
Cbx5Chromobox protein homolog 5. (164 aa)
Knl1Protein CASC5. (1996 aa)
Terb2Uncharacterized protein C15orf43 homolog. (221 aa)
Fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
Nup43Nucleoporin Nup43. (127 aa)
Tox4TOX high mobility group box family member 4. (545 aa)
Gpatch11G patch domain-containing protein 11 isoform X1. (263 aa)
Sycp2lSynaptonemal complex protein 2-like. (433 aa)
CenpeCentromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2437 aa)
Recql4ATP-dependent DNA helicase Q4 isoform X2. (1189 aa)
Clasp2CLIP-associating protein 2. (1255 aa)
CenpiCentromere protein I. (711 aa)
Tep1Telomerase protein component 1 isoform X3. (1897 aa)
CenpuCentromere protein U. (281 aa)
WrnWerner syndrome ATP-dependent helicase. (1377 aa)
Nup37Nucleoporin Nup37. (327 aa)
Chmp3Charged multivesicular body protein 3. (221 aa)
Bub3Mitotic checkpoint protein BUB3 isoform X2. (327 aa)
Kat8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (304 aa)
Nuf2Kinetochore protein Nuf2. (455 aa)
Ppp1ccSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (312 aa)
Ikzf1DNA-binding protein Ikaros isoform X7. (199 aa)
Smc1bStructural maintenance of chromosomes protein. (1110 aa)
Hat1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
Spag5Sperm-associated antigen 5. (1148 aa)
Zfp330Zinc finger protein 330. (321 aa)
Nsmce1Non-structural maintenance of chromosomes element 1 homolog. (263 aa)
Polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1047 aa)
ENSDORP00000009450annotation not available (32 aa)
IncenpInner centromere protein isoform X2. (790 aa)
Fbxw11F-box/WD repeat-containing protein 11 isoform X1. (541 aa)
Zbtb48Zinc finger and BTB domain-containing protein 48 isoform X2. (685 aa)
AurkbAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (343 aa)
Nsmce2E3 SUMO-protein ligase NSE2 isoform X2. (246 aa)
PmlProtein PML isoform X1. (830 aa)
Chek2Serine/threonine-protein kinase Chk2. (467 aa)
Dna2DNA replication ATP-dependent helicase/nuclease DNA2. (1044 aa)
Baz1aBromodomain adjacent to zinc finger domain protein 1A. (1524 aa)
Wrap53Telomerase Cajal body protein 1. (539 aa)
Dctn4Dynactin subunit 4. (467 aa)
Zfp827Zinc finger protein 827. (984 aa)
Ercc1DNA excision repair protein ERCC-1 isoform X2. (298 aa)
Ppp2cbSerine/threonine-protein phosphatase. (309 aa)
Ercc6lDNA excision repair protein ERCC-6-like. (1235 aa)
CenpwCentromere protein W. (88 aa)
Bub1bMitotic checkpoint serine/threonine-protein kinase BUB1 beta. (912 aa)
Orc2Origin recognition complex subunit 2. (563 aa)
Chmp7Charged multivesicular body protein 7. (396 aa)
Dctn2Dynactin subunit 2 isoform X2. (402 aa)
Mad1l1Mitotic spindle assembly checkpoint protein MAD1 isoform X1. (717 aa)
Dsn1Kinetochore-associated protein DSN1 homolog isoform X2. (282 aa)
Cfdp1Craniofacial development protein 1; May play a role during embryogenesis. (299 aa)
Spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (553 aa)
Chmp5Charged multivesicular body protein 5. (219 aa)
Tfip11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
CenpcCentromere protein C isoform X1. (876 aa)
Xrcc1DNA repair protein XRCC1. (642 aa)
Nup133Nuclear pore complex protein Nup133. (817 aa)
Stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (365 aa)
Lrwd1Leucine-rich repeat and WD repeat-containing protein 1 isoform X2. (642 aa)
CenphCentromere protein H. (183 aa)
KnstrnSmall kinetochore-associated protein. (245 aa)
Seh1lNucleoporin SEH1 isoform X1; Belongs to the WD repeat SEC13 family. (360 aa)
Cbx3Chromobox protein homolog 3. (117 aa)
Ska3Spindle and kinetochore-associated protein 3 isoform X2. (400 aa)
Spc25Kinetochore protein Spc25. (226 aa)
Rad21Double-strand-break repair protein rad21 homolog. (631 aa)
Nup107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (876 aa)
Nup85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (657 aa)
Rcc2Protein RCC2. (427 aa)
Ndel1Nuclear distribution protein nudE-like 1 isoform X3. (345 aa)
Mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (203 aa)
Clasp1CLIP-associating protein 1 isoform X1. (1531 aa)
TprNucleoprotein TPR isoform X1. (556 aa)
Terf2ipTelomeric repeat-binding factor 2-interacting protein 1. (392 aa)
Pot1Protection of telomeres protein 1 isoform X4. (542 aa)
Smc1aStructural maintenance of chromosomes protein 1A. (990 aa)
Suv39h2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (399 aa)
CenppCentromere protein P. (195 aa)
Birc5Baculoviral IAP repeat-containing protein 5. (142 aa)
Nup160Nuclear pore complex protein Nup160 isoform X1. (1427 aa)
Pinx1PIN2/TERF1-interacting telomerase inhibitor 1. (330 aa)
Mta2Metastasis-associated protein MTA2. (561 aa)
Wrnip1ATPase WRNIP1 isoform X1. (663 aa)
Nsmce4aNon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (287 aa)
CenpbMajor centromere autoantigen B. (595 aa)
Spo11Meiotic recombination protein SPO11 isoform X1. (396 aa)
Rpa2Replication protein A 32 kDa subunit isoform X1. (255 aa)
Trappc12Trafficking protein particle complex subunit 12. (783 aa)
Smarca5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (959 aa)
Sirt6NAD-dependent protein deacetylase sirtuin-6. (328 aa)
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Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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