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Syt11 Syt11 Slc6a7 Slc6a7 Nectin1 Nectin1 Stx1a Stx1a Cacna1e Cacna1e Gabbr2 Gabbr2 Psen2 Psen2 Psen1 Psen1 Gria1 Gria1 Cdh9 Cdh9 P2rx1 P2rx1 Scn10a Scn10a Ncstn Ncstn Ptprs Ptprs Scn1a Scn1a Gria3 Gria3 Cdh2 Cdh2 Grm3 Grm3 Slc1a6 Slc1a6 Kcna3 Kcna3 Kcna2 Kcna2 Gria2 Gria2 Nptn Nptn Epha4 Epha4 Kcnh1 Kcnh1 Kcnc4 Kcnc4 Grm8 Grm8 Adcy8 Adcy8 Chrm2 Chrm2 Atp1a3 Atp1a3 Cdh10 Cdh10 Cadm3 Cadm3 Cnr1 Cnr1 ENSDORP00000027334 ENSDORP00000027334 Gabra5 Gabra5 Pcdh17 Pcdh17 Chrna7 Chrna7 Cadm1 Cadm1 Efnb1 Efnb1 Slc6a3 Slc6a3 Kcnc3 Kcnc3 Efnb3 Efnb3 Prrt2 Prrt2 Glra1 Glra1 Syt7 Syt7 Grin1 Grin1 Chrm4 Chrm4 Chrna6 Chrna6 Atp2b2 Atp2b2 Cacna1h Cacna1h Cacna1a Cacna1a Grik4 Grik4 Slc1a7 Slc1a7 Grik1 Grik1 Cntnap4 Cntnap4 Fxyd6 Fxyd6 Efnb2 Efnb2 Grin2a Grin2a Slc6a5 Slc6a5 Aph1a Aph1a Gpm6a Gpm6a Chrm3 Chrm3 Ephb2 Ephb2 Kcna1 Kcna1 Erbb4 Erbb4 Atp2b3 Atp2b3 Kcnc1 Kcnc1 Drd2 Drd2 Atp2b4 Atp2b4 Adgrl1 Adgrl1 P2ry2 P2ry2 Ncam1 Ncam1 Scn8a Scn8a Slc6a1 Slc6a1 Slc6a11 Slc6a11 Lrfn3 Lrfn3 Scn11a Scn11a P2rx3 P2rx3 ENSDORP00000016518 ENSDORP00000016518 Grm7 Grm7 Ptprd Ptprd Kcnj3 Kcnj3 Psenen Psenen Htr1a Htr1a Grik5 Grik5 Chrm1 Chrm1 Kcna4 Kcna4 Drd1 Drd1 Lpar2 Lpar2 Nrxn1 Nrxn1 Slc6a9 Slc6a9 Gabbr1 Gabbr1 Chrnb2 Chrnb2 Kcnma1 Kcnma1 Atp2b1 Atp2b1 Adam23 Adam23 Chrna4 Chrna4 Cacna1c Cacna1c Slc1a2 Slc1a2 Canx Canx Kcnj9 Kcnj9 ENSDORP00000020814 ENSDORP00000020814 Htr1b Htr1b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Syt11Synaptotagmin-11. (431 aa)
Slc6a7Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (625 aa)
Nectin1Nectin-1. (505 aa)
Stx1asyntaxin-1A; Belongs to the syntaxin family. (288 aa)
Cacna1eVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2325 aa)
Gabbr2Gamma-aminobutyric acid type B receptor subunit 2. (954 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
Gria1Glutamate receptor 1 isoform X2. (906 aa)
Cdh9Cadherin-9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
P2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
Scn10aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1937 aa)
NcstnNicastrin. (698 aa)
PtprsReceptor-type tyrosine-protein phosphatase S. (1430 aa)
Scn1aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1998 aa)
Gria3Glutamate receptor 3 isoform X2. (894 aa)
Cdh2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (886 aa)
Grm3Metabotropic glutamate receptor 3. (882 aa)
Slc1a6Amino acid transporter. (544 aa)
Kcna3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (509 aa)
Kcna2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
Gria2Glutamate receptor 2. (842 aa)
NptnNeuroplastin. (397 aa)
Epha4Ephrin type-A receptor 4 isoform X1. (986 aa)
Kcnh1Potassium voltage-gated channel subfamily H member 1 isoform X1. (990 aa)
Kcnc4Potassium voltage-gated channel subfamily C member 4 isoform X2; Belongs to the potassium channel family. (630 aa)
Grm8Metabotropic glutamate receptor 8 isoform X1. (908 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
Chrm2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
Atp1a3Sodium/potassium-transporting ATPase subunit alpha. (1035 aa)
Cdh10Cadherin-10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
Cadm3Cell adhesion molecule 3 isoform X2. (396 aa)
Cnr1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (471 aa)
ENSDORP00000027334annotation not available (103 aa)
Gabra5Gamma-aminobutyric acid receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
Pcdh17Protocadherin-17. (1162 aa)
Chrna7Neuronal acetylcholine receptor subunit alpha-7. (568 aa)
Cadm1Cell adhesion molecule 1 isoform X1. (474 aa)
Efnb1ephrin-B1; Belongs to the ephrin family. (345 aa)
Slc6a3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (635 aa)
Kcnc3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (709 aa)
Efnb3ephrin-B3; Belongs to the ephrin family. (340 aa)
Prrt2Proline-rich transmembrane protein 2. (61 aa)
Glra1Glycine receptor subunit alpha-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
Syt7Synaptotagmin 7. (556 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
Chrm4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa)
Chrna6Neuronal acetylcholine receptor subunit alpha-6. (494 aa)
Atp2b2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
Cacna1hVoltage-dependent T-type calcium channel subunit alpha-1H. (2166 aa)
Cacna1aVoltage-dependent P/Q-type calcium channel subunit alpha-1A. (2254 aa)
Grik4Glutamate receptor ionotropic, kainate 4. (765 aa)
Slc1a7Amino acid transporter. (558 aa)
Grik1Glutamate receptor ionotropic, kainate 1 isoform X1. (926 aa)
Cntnap4Contactin-associated protein-like 4 isoform X1. (1310 aa)
Fxyd6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa)
Efnb2ephrin-B2; Belongs to the ephrin family. (325 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1301 aa)
Slc6a5Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (806 aa)
Aph1aGamma-secretase subunit APH-1A. (265 aa)
Gpm6aNeuronal membrane glycoprotein M6-a. (278 aa)
Chrm3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
Ephb2Ephrin type-B receptor 2 isoform X2. (1018 aa)
Kcna1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (496 aa)
Erbb4Receptor protein-tyrosine kinase. (1308 aa)
Atp2b3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1085 aa)
Kcnc1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
Drd2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
Atp2b4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1230 aa)
Adgrl1Latrophilin-1; Belongs to the G-protein coupled receptor 2 family. (1041 aa)
P2ry2p2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
Ncam1Neural cell adhesion molecule 1. (848 aa)
Scn8aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1982 aa)
Slc6a1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
Slc6a11Sodium- and chloride-dependent GABA transporter 3. (590 aa)
Lrfn3Leucine-rich repeat and fibronectin type-III domain-containing protein 3. (522 aa)
Scn11aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1620 aa)
P2rx3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
ENSDORP00000016518annotation not available (92 aa)
Grm7Metabotropic glutamate receptor 7 isoform X1. (918 aa)
PtprdReceptor-type tyrosine-protein phosphatase delta isoform X3. (1912 aa)
Kcnj3G protein-activated inward rectifier potassium channel 1 isoform X1. (502 aa)
PsenenGamma-secretase subunit PEN-2. (101 aa)
Htr1a5-hydroxytryptamine receptor 1A. (422 aa)
Grik5Glutamate receptor ionotropic, kainate 5. (985 aa)
Chrm1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
Kcna4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (653 aa)
Drd1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (447 aa)
Lpar2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (349 aa)
Nrxn1Neurexin-1-beta isoform X1. (1515 aa)
Slc6a9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (664 aa)
Gabbr1Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (961 aa)
Chrnb2Neuronal acetylcholine receptor subunit beta-2 isoform X1. (504 aa)
Kcnma1Calcium-activated potassium channel subunit alpha-1. (1132 aa)
Atp2b1Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1019 aa)
Adam23Disintegrin and metalloproteinase domain-containing protein 23. (820 aa)
Chrna4Neuronal acetylcholine receptor subunit alpha-4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (625 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
Slc1a2Amino acid transporter. (573 aa)
CanxCalnexin. (560 aa)
Kcnj9G protein-activated inward rectifier potassium channel 3. (393 aa)
ENSDORP00000020814annotation not available (97 aa)
Htr1b5-hydroxytryptamine receptor 1B. (394 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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