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| | Derl1 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (213 aa) |
| | Insig2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | Srebf2 | Sterol regulatory element-binding protein 2. (1144 aa) |
| | Srprb | Signal recognition particle receptor subunit beta. (257 aa) |
| | Sec61a1 | Protein transport protein Sec61 subunit alpha isoform 1. (478 aa) |
| | Selenos | Selenoprotein S. (187 aa) |
| | Ern1 | Serine/threonine-protein kinase/endoribonuclease IRE1. (406 aa) |
| | Map3k5 | Mitogen-activated protein kinase kinase kinase 5. (144 aa) |
| | Fam8a1 | Protein FAM8A1. (351 aa) |
| | Tmem258 | Transmembrane protein 258. (79 aa) |
| | Sec63 | Translocation protein SEC63 homolog. (737 aa) |
| | Sptlc1 | Serine palmitoyltransferase 1 isoform X1. (473 aa) |
| | Ppib | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (208 aa) |
| | Syvn1 | E3 ubiquitin-protein ligase synoviolin. (607 aa) |
| | Traf2 | TNF receptor-associated factor. (484 aa) |
| | Dnajc10 | DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (793 aa) |
| | Sdf2l1 | Stromal cell-derived factor 2-like protein 1. (221 aa) |
| | Pdia4 | Protein disulfide-isomerase A4. (634 aa) |
| | Amfr | E3 ubiquitin-protein ligase AMFR. (620 aa) |
| | Sec11c | Signal peptidase complex catalytic subunit SEC11. (192 aa) |
| | Hsp90b1 | Endoplasmin. (804 aa) |
| | Pigp | Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. (157 aa) |
| | Emc1 | ER membrane protein complex subunit 1 isoform X3. (995 aa) |
| | Ssr4 | Translocon-associated protein subunit delta isoform X1. (173 aa) |
| | Sec61g | Protein transport protein Sec61 subunit gamma. (68 aa) |
| | Ufd1 | Ubiquitin fusion degradation protein 1 homolog isoform X1. (308 aa) |
| | Emc2 | ER membrane protein complex subunit 2. (297 aa) |
| | Abcb9 | ATP-binding cassette sub-family B member 9 isoform X1. (766 aa) |
| | Tusc3 | Tumor suppressor candidate 3. (347 aa) |
| | Ddost | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (442 aa) |
| | Pigk | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (397 aa) |
| | Emc3 | ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa) |
| | Pigh | Phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform X1. (188 aa) |
| | Piga | Phosphatidylinositol N-acetylglucosaminyltransferase subunit A. (485 aa) |
| | Sel1l | Protein sel-1 homolog 1 isoform X1. (793 aa) |
| | Dad1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa) |
| | Tap2 | Antigen peptide transporter 2. (704 aa) |
| | Emc4 | ER membrane protein complex subunit 4; Belongs to the EMC4 family. (175 aa) |
| | Gpaa1 | Glycosylphosphatidylinositol anchor attachment 1 protein. (596 aa) |
| | Sptlc2 | Serine palmitoyltransferase 2. (557 aa) |
| | Rnf139 | E3 ubiquitin-protein ligase RNF139. (671 aa) |
| | Alg14 | UDP-N-acetylglucosamine transferase subunit ALG14 homolog. (213 aa) |
| | Faf2 | LOW QUALITY PROTEIN: FAS-associated factor 2. (392 aa) |
| | Emc7 | ER membrane protein complex subunit 7. (75 aa) |
| | Emc9 | ER membrane protein complex subunit 9. (206 aa) |
| | Ubxn1 | UBX domain-containing protein 1. (297 aa) |
| | Dnajb11 | dnaJ homolog subfamily B member 11. (355 aa) |
| | Stt3b | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B. (752 aa) |
| | Spcs3 | Signal peptidase complex subunit 3. (180 aa) |
| | Sptlc3 | Serine palmitoyltransferase 3. (559 aa) |
| | Nploc4 | Nuclear protein localization protein 4 homolog. (603 aa) |
| | Ganab | Neutral alpha-glucosidase AB isoform X1; Belongs to the glycosyl hydrolase 31 family. (966 aa) |
| | Krtcap2 | Keratinocyte-associated protein 2. (136 aa) |
| | Pigm | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (420 aa) |
| | P4hb | Protein disulfide-isomerase. (485 aa) |
| | Nbas | Neuroblastoma-amplified sequence. (2341 aa) |
| | H13 | Minor histocompatibility antigen H13 isoform X1. (374 aa) |
| | Stt3a | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A. (602 aa) |
| | Aup1 | Ancient ubiquitous protein 1 isoform X1. (421 aa) |
| | Emc6 | ER membrane protein complex subunit 6. (110 aa) |
| | ENSDORP00000012985 | annotation not available (99 aa) |
| | Tapbp | Tapasin. (435 aa) |
| | Pdia3 | Protein disulfide-isomerase. (505 aa) |
| | Get3 | ATPase Asna1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (348 aa) |
| | Faf1 | FAS-associated factor 1. (498 aa) |
| | Pigt | GPI transamidase component PIG-T. (584 aa) |
| | Emc8 | ER membrane protein complex subunit 8. (196 aa) |
| | Srpra | Signal recognition particle receptor subunit alpha. (637 aa) |
| | Rpn2 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (630 aa) |
| | Elovl6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | Pigy | Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y. (71 aa) |
| | Sptssb | Serine palmitoyltransferase small subunit B. (76 aa) |
| | ENSDORP00000017178 | annotation not available (304 aa) |
| | Dpm2 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (83 aa) |
| | Fkbp1a | Peptidylprolyl isomerase. (108 aa) |
| | Tap1 | Antigen peptide transporter 1. (682 aa) |
| | ENSDORP00000017546 | annotation not available (173 aa) |
| | Prkcsh | Glucosidase 2 subunit beta. (507 aa) |
| | Derl2 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa) |
| | Ubxn7 | UBX domain-containing protein 7. (489 aa) |
| | Mmgt1 | Membrane magnesium transporter 1 isoform X2. (131 aa) |
| | Ern2 | Serine/threonine-protein kinase/endoribonuclease IRE2. (981 aa) |
| | Pigu | Phosphatidylinositol glycan anchor biosynthesis class U protein. (435 aa) |
| | Ostc | Oligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (149 aa) |
| | Pigc | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C. (297 aa) |
| | P4ha2 | Prolyl 4-hydroxylase subunit alpha-2 isoform X4. (535 aa) |
| | Spcs1 | Signal peptidase complex subunit 1. (102 aa) |
| | Pigs | GPI transamidase component PIG-S. (539 aa) |
| | Zw10 | Centromere/kinetochore protein zw10 homolog. (749 aa) |
| | Magt1 | Magnesium transporter protein 1. (337 aa) |
| | Hsd17b12 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | Rnf125 | E3 ubiquitin-protein ligase RNF125. (232 aa) |
| | Map3k6 | Mitogen-activated protein kinase kinase kinase 6. (1298 aa) |
| | Pigq | Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q isoform X1. (581 aa) |
| | Mlec | Malectin. (254 aa) |
| | Ryr1 | Ryanodine receptor 1. (4894 aa) |
| | Sec61b | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa) |
| | Derl3 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (229 aa) |
| | Calr | Calreticulin. (417 aa) |
| | Rpn1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (556 aa) |
| | Ormdl1 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | Get1 | Tail-anchored protein insertion receptor WRB. (174 aa) |
| | Caml | Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (295 aa) |
| | Sec61a2 | Protein transport protein Sec61 subunit alpha isoform 2. (476 aa) |
| | ENSDORP00000023958 | annotation not available (296 aa) |
| | Emc10 | ER membrane protein complex subunit 10. (277 aa) |
| | Insig1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (237 aa) |
| | Sptssa | Serine palmitoyltransferase small subunit A. (71 aa) |
| | Arl6ip1 | ADP-ribosylation factor-like protein 6-interacting protein 1. (203 aa) |
| | Spcs2 | Signal peptidase complex subunit 2. (227 aa) |
| | Ost4 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4. (37 aa) |
| | Hyou1 | Hypoxia up-regulated protein 1. (227 aa) |
| | P4ha1 | Prolyl 4-hydroxylase subunit alpha-1 isoform X1. (534 aa) |
| | Rint1 | RAD50-interacting protein 1. (793 aa) |
| | Vcp | Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (806 aa) |
| | Ormdl2 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | Ext2 | Exostosin-2; Belongs to the glycosyltransferase 47 family. (718 aa) |
| | Ormdl3 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
