(18 nodes) Embryonic brain development network (Dipodomys ordii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Slc6a8	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (635 aa)
	ENSDORP00000020585	annotation not available (80 aa)
	Ift140	Intraflagellar transport protein 140 homolog. (1494 aa)
	Cc2d2a	Coiled-coil and C2 domain-containing protein 2A. (1580 aa)
	Cdk20	Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily. (346 aa)
	Med12	Mediator of RNA polymerase II transcription subunit 12. (2183 aa)
	Wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	Pcnt	Pericentrin. (2788 aa)
	Tbc1d23	TBC1 domain family member 23 isoform X1. (699 aa)
	LOC105998890	Transformer-2 protein homolog beta pseudogene. (260 aa)
	Tra2b	Transformer-2 protein homolog beta isoform X1. (288 aa)
	Ppil1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
	Cdc40	pre-mRNA-processing factor 17 isoform X1. (579 aa)
	En1	Homeobox protein engrailed-like. (140 aa)
	En2	Homeobox protein engrailed-like. (185 aa)
	Ttbk2	Tau-tubulin kinase 2. (436 aa)
	Rnf112	RING finger protein 112. (677 aa)
	Mks1	Meckel syndrome type 1 protein. (559 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cc2d2a	Mks1	ENSDORP00000016194	ENSDORP00000020415	Coiled-coil and C2 domain-containing protein 2A.	Meckel syndrome type 1 protein.	0.897
Cdc40	LOC105998890	ENSDORP00000024487	ENSDORP00000025381	pre-mRNA-processing factor 17 isoform X1.	Transformer-2 protein homolog beta pseudogene.	0.533
Cdc40	Ppil1	ENSDORP00000024487	ENSDORP00000027195	pre-mRNA-processing factor 17 isoform X1.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.999
Cdc40	Tra2b	ENSDORP00000024487	ENSDORP00000026279	pre-mRNA-processing factor 17 isoform X1.	Transformer-2 protein homolog beta isoform X1.	0.533
ENSDORP00000020585	Med12	ENSDORP00000020585	ENSDORP00000009231	annotation not available	Mediator of RNA polymerase II transcription subunit 12.	0.516
ENSDORP00000020585	Ttbk2	ENSDORP00000020585	ENSDORP00000020030	annotation not available	Tau-tubulin kinase 2.	0.436
ENSDORP00000020585	Wnt1	ENSDORP00000020585	ENSDORP00000007249	annotation not available	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.867
En1	En2	ENSDORP00000017456	ENSDORP00000017540	Homeobox protein engrailed-like.	Homeobox protein engrailed-like.	0.705
En1	Wnt1	ENSDORP00000017456	ENSDORP00000007249	Homeobox protein engrailed-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.433
En2	En1	ENSDORP00000017540	ENSDORP00000017456	Homeobox protein engrailed-like.	Homeobox protein engrailed-like.	0.705
LOC105998890	Cdc40	ENSDORP00000025381	ENSDORP00000024487	Transformer-2 protein homolog beta pseudogene.	pre-mRNA-processing factor 17 isoform X1.	0.533
Med12	ENSDORP00000020585	ENSDORP00000009231	ENSDORP00000020585	Mediator of RNA polymerase II transcription subunit 12.	annotation not available	0.516
Mks1	Cc2d2a	ENSDORP00000020415	ENSDORP00000016194	Meckel syndrome type 1 protein.	Coiled-coil and C2 domain-containing protein 2A.	0.897
Ppil1	Cdc40	ENSDORP00000027195	ENSDORP00000024487	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	pre-mRNA-processing factor 17 isoform X1.	0.999
Tra2b	Cdc40	ENSDORP00000026279	ENSDORP00000024487	Transformer-2 protein homolog beta isoform X1.	pre-mRNA-processing factor 17 isoform X1.	0.533
Ttbk2	ENSDORP00000020585	ENSDORP00000020030	ENSDORP00000020585	Tau-tubulin kinase 2.	annotation not available	0.436
Wnt1	ENSDORP00000020585	ENSDORP00000007249	ENSDORP00000020585	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	annotation not available	0.867
Wnt1	En1	ENSDORP00000007249	ENSDORP00000017456	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Homeobox protein engrailed-like.	0.433