STRINGSTRING
Pitpnm1 Pitpnm1 Tjp2 Tjp2 Bmpr2 Bmpr2 Gab2 Gab2 Cblb Cblb Shc4 Shc4 Rack1 Rack1 Elmo2 Elmo2 Phyhip Phyhip Khdrbs1 Khdrbs1 Fer Fer Gas6 Gas6 Plcg1 Plcg1 Rnf41 Rnf41 Csk Csk Map3k7 Map3k7 Acvr1 Acvr1 Angpt1 Angpt1 Flt3lg Flt3lg Acp4 Acp4 Tob1 Tob1 Nck1 Nck1 Pitpnm2 Pitpnm2 Dnaja3 Dnaja3 Tradd Tradd Plcg2 Plcg2 Fnta Fnta Ptpn14 Ptpn14 ENSDORP00000016855 ENSDORP00000016855 Tiam1 Tiam1 Arhgef16 Arhgef16 Jup Jup Ctnnd1 Ctnnd1 ENSDORP00000018119 ENSDORP00000018119 Nrg1 Nrg1 Frs2 Frs2 Gdnf Gdnf LOC106001529 LOC106001529 Grb14 Grb14 Pik3r1 Pik3r1 Cbl Cbl Socs5 Socs5 LOC105990085 LOC105990085 Crkl Crkl LOC105984826 LOC105984826 Pcna Pcna Dok2 Dok2 Crk Crk Zpr1 Zpr1 Ywhag Ywhag Dusp22 Dusp22 Stap1 Stap1 Nedd9 Nedd9 Cpne3 Cpne3 Cadm4 Cadm4 Rasa1 Rasa1 Shc2 Shc2 Lrp4 Lrp4 Alkal1 Alkal1 Cdh1 Cdh1 Dscam Dscam Clasp2 Clasp2 Pspn Pspn Bank1 Bank1 Eif3a Eif3a Cdh2 Cdh2 Nck2 Nck2 Fiz1 Fiz1 Shc1 Shc1 Mast3 Mast3 Epha4 Epha4 Angpt2 Angpt2 Shc3 Shc3 Ptprf Ptprf Sh2b2 Sh2b2 LOC105998123 LOC105998123 Itgax Itgax Anxa5 Anxa5 Pten Pten Angpt4 Angpt4 Ptpn11 Ptpn11 Cass4 Cass4 Itgb1 Itgb1 Pitpnm3 Pitpnm3 Mst1 Mst1 Ntrk2 Ntrk2 Dock4 Dock4 Sirpa Sirpa Ptpn1 Ptpn1 Ptpn2 Ptpn2 Dusp3 Dusp3 Trp53 Trp53 Cd247 Cd247 Trem2 Trem2 ENSDORP00000025178 ENSDORP00000025178 Phyhipl Phyhipl Dazap2 Dazap2 Sh2b1 Sh2b1 LOC106000544 LOC106000544 Grb2 Grb2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pitpnm1Membrane-associated phosphatidylinositol transfer protein 1. (252 aa)
Tjp2Tight junction protein ZO-2 isoform X1; Belongs to the MAGUK family. (1154 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (933 aa)
Gab2GRB2-associated-binding protein 2. (608 aa)
CblbE3 ubiquitin-protein ligase CBL-B isoform X2. (939 aa)
Shc4SHC-transforming protein 4. (340 aa)
Rack1Guanine nucleotide-binding protein subunit beta-2-like 1. (317 aa)
Elmo2Engulfment and cell motility protein 2 isoform X1. (732 aa)
Phyhipphytanoyl-CoA hydroxylase-interacting protein. (331 aa)
Khdrbs1KH domain-containing, RNA-binding, signal transduction-associated protein 1. (441 aa)
FerTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (775 aa)
Gas6Growth arrest-specific protein 6. (660 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Rnf41E3 ubiquitin-protein ligase NRDP1. (317 aa)
CskTyrosine-protein kinase. (450 aa)
Map3k7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (596 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
Angpt1Angiopoietin-1 isoform X1. (498 aa)
Flt3lgFms-related tyrosine kinase 3 ligand isoform X1. (181 aa)
Acp4Testicular acid phosphatase; Belongs to the histidine acid phosphatase family. (428 aa)
Tob1Protein Tob1. (345 aa)
Nck1Cytoplasmic protein. (377 aa)
Pitpnm2Membrane-associated phosphatidylinositol transfer protein 2 isoform X3. (1269 aa)
Dnaja3dnaJ homolog subfamily A member 3, mitochondrial isoform X1. (480 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein. (309 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
FntaProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha. (379 aa)
Ptpn14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (847 aa)
ENSDORP00000016855annotation not available (311 aa)
Tiam1T-lymphoma invasion and metastasis-inducing protein 1. (1588 aa)
Arhgef16Rho guanine nucleotide exchange factor 16. (708 aa)
JupJunction plakoglobin isoform X1. (745 aa)
Ctnnd1Catenin delta-1 isoform X1. (964 aa)
ENSDORP00000018119annotation not available (310 aa)
Nrg1Pro-neuregulin-1, membrane-bound isoform isoform X1. (700 aa)
Frs2Fibroblast growth factor receptor substrate 2. (507 aa)
GdnfGlial cell line-derived neurotrophic factor isoform X1. (240 aa)
LOC106001529Mitogen-activated protein kinase kinase kinase 7-like. (538 aa)
Grb14Growth factor receptor-bound protein 14. (507 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
Socs5Suppressor of cytokine signaling 5. (536 aa)
LOC105990085Tyrosine-protein phosphatase non-receptor type. (333 aa)
CrklCrk-like protein. (303 aa)
LOC105984826Guanine nucleotide-binding protein subunit beta-2-like 1 pseudogene. (259 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Dok2Docking protein 2. (404 aa)
CrkAdapter molecule crk. (304 aa)
Zpr1Zinc finger protein ZPR1 isoform X1. (459 aa)
Ywhag14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
Dusp22Dual specificity protein phosphatase 22 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa)
Stap1Signal-transducing adaptor protein 1 isoform X1. (301 aa)
Nedd9Enhancer of filamentation 1 isoform X3. (834 aa)
Cpne3LOW QUALITY PROTEIN: copine-3. (439 aa)
Cadm4Cell adhesion molecule 4. (380 aa)
Rasa1Ras GTPase-activating protein 1. (813 aa)
Shc2SHC-transforming protein 2. (513 aa)
Lrp4Low-density lipoprotein receptor-related protein 4. (1882 aa)
Alkal1Protein FAM150A. (128 aa)
Cdh1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (881 aa)
DscamDown syndrome cell adhesion molecule. (1997 aa)
Clasp2CLIP-associating protein 2. (1255 aa)
PspnPersephin. (159 aa)
Bank1B-cell scaffold protein with ankyrin repeats. (783 aa)
Eif3aEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1338 aa)
Cdh2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (886 aa)
Nck2Cytoplasmic protein. (380 aa)
Fiz1Flt3-interacting zinc finger protein 1. (288 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Epha4Ephrin type-A receptor 4 isoform X1. (986 aa)
Angpt2Angiopoietin-2. (495 aa)
Shc3SHC-transforming protein 3. (598 aa)
PtprfReceptor-type tyrosine-protein phosphatase F isoform X1. (1901 aa)
Sh2b2SH2B adapter protein 2. (436 aa)
LOC105998123Carcinoembryonic antigen-related cell adhesion molecule 1-like isoform X1. (483 aa)
ItgaxIntegrin alpha-X; Belongs to the integrin alpha chain family. (1145 aa)
Anxa5Annexin. (321 aa)
PtenPhosphatase and tensin homolog. (396 aa)
Angpt4Angiopoietin-4. (499 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Cass4Cas scaffolding protein family member 4. (743 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Pitpnm3Membrane-associated phosphatidylinositol transfer protein 3. (971 aa)
Mst1Hepatocyte growth factor-like protein isoform X1; Belongs to the peptidase S1 family. Plasminogen subfamily. (708 aa)
Ntrk2Tyrosine-protein kinase receptor. (821 aa)
Dock4Dedicator of cytokinesis protein 4; Belongs to the DOCK family. (1971 aa)
SirpaTyrosine-protein phosphatase non-receptor type substrate 1. (216 aa)
Ptpn1Tyrosine-protein phosphatase non-receptor type. (436 aa)
Ptpn2Tyrosine-protein phosphatase non-receptor type 2. (397 aa)
Dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
Trp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa)
Cd247T-cell surface glycoprotein CD3 zeta chain isoform X1. (164 aa)
Trem2Triggering receptor expressed on myeloid cells 2. (251 aa)
ENSDORP00000025178annotation not available (40 aa)
Phyhiplphytanoyl-CoA hydroxylase-interacting protein-like. (376 aa)
Dazap2DAZ-associated protein 2. (168 aa)
Sh2b1SH2B adapter protein 1 isoform X3. (726 aa)
LOC106000544NADPH oxidase 4-like. (135 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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