STRINGSTRING
Mef2c Mef2c Kcnc2 Kcnc2 Pkd2 Pkd2 Kcne2 Kcne2 Cacna2d1 Cacna2d1 Rasgrf2 Rasgrf2 Kcne4 Kcne4 Cacnb2 Cacnb2 Crhbp Crhbp Oprm1 Oprm1 Cnih2 Cnih2 Pla2g6 Pla2g6 R3hdm1 R3hdm1 Dapk1 Dapk1 Lrrc55 Lrrc55 Ifngr1 Ifngr1 Vamp2 Vamp2 Gem Gem Gnb5 Gnb5 Stac2 Stac2 Selenon Selenon Nipsnap2 Nipsnap2 Fgf12 Fgf12 Fam173a Fam173a Kcnq1 Kcnq1 Rem2 Rem2 Stac Stac Cacng5 Cacng5 Hap1 Hap1 Cdk5 Cdk5 Hpcal1 Hpcal1 Kcns2 Kcns2 Nlgn3 Nlgn3 Itgb1 Itgb1 Kcng1 Kcng1 Nlgn2 Nlgn2 Fgf11 Fgf11 Stimate Stimate Homer1 Homer1 Abcc8 Abcc8 Kif5b Kif5b Cfl1 Cfl1 Ptk2b Ptk2b Hpca Hpca Bmp4 Bmp4 Pde4b Pde4b Cacng2 Cacng2 Kcnk3 Kcnk3 Cacng4 Cacng4 Ctss Ctss Neto2 Neto2 Stac3 Stac3 R3hdm2 R3hdm2 Grin2a Grin2a Akap6 Akap6 Ephb2 Ephb2 Plcg1 Plcg1 Fmr1 Fmr1 LOC106001740 LOC106001740 Kcna1 Kcna1 Cacnb3 Cacnb3 Ikbkb Ikbkb Prrt1 Prrt1 LOC105980465 LOC105980465 Casq1 Casq1 Kcnc1 Kcnc1 Cacng3 Cacng3 Drd2 Drd2 Rrad Rrad Crh Crh Lrrc52 Lrrc52 Crbn Crbn Nppa Nppa Snx27 Snx27 Ednra Ednra Cabp2 Cabp2 Cabp4 Cabp4 Epo Epo Mapk8ip2 Mapk8ip2 Asic2 Asic2 Neto1 Neto1 Plcg2 Plcg2 Actn2 Actn2 Hcn1 Hcn1 Rgs9 Rgs9 Ppargc1a Ppargc1a Cacnb1 Cacnb1 Stim2 Stim2 Nedd4l Nedd4l Shisa6 Shisa6 Stoml1 Stoml1 Shank1 Shank1 Abcc9 Abcc9 P2ry6 P2ry6 Sri Sri Rem1 Rem1 Cnih3 Cnih3 Htt Htt Reln Reln Gpr35 Gpr35 Arc Arc Cbarp Cbarp Fkbp1a Fkbp1a Scn1b Scn1b Slmap Slmap Casq2 Casq2 LOC106002211 LOC106002211 Rnf207 Rnf207 Amigo3 Amigo3 Nlgn1 Nlgn1 Akap7 Akap7 Pink1 Pink1 Nrxn1 Nrxn1 Lrrc38 Lrrc38 ENSDORP00000018748 ENSDORP00000018748 Kcne3 Kcne3 Pln Pln Slc6a9 Slc6a9 Gsg1l Gsg1l Crhr1 Crhr1 Cacnb4 Cacnb4 Ank3 Ank3 LOC106002162 LOC106002162 Chrna4 Chrna4 Klhl24 Klhl24 S100a1 S100a1 Pde4d Pde4d Mtnr1b Mtnr1b Cacng8 Cacng8 ENSDORP00000020658 ENSDORP00000020658 Stim2-2 Stim2-2 Drd3 Drd3 Cabp5 Cabp5 Dmd Dmd Jsrp1 Jsrp1 Ifngr2 Ifngr2 Cacna1a Cacna1a Dlg4 Dlg4 Rph3a Rph3a Hrc Hrc Trem2 Trem2 Stim1 Stim1 Kcnab1 Kcnab1 ENSDORP00000023261 ENSDORP00000023261 Kcne1 Kcne1 Shank3 Shank3 Cacng7 Cacng7 Fgf13 Fgf13 LOC105994343 LOC105994343 Shisa9 Shisa9 Mink1 Mink1 Cacna1f Cacna1f Stom Stom R3hdm1-2 R3hdm1-2 Ccr2 Ccr2 Sumo1 Sumo1 Edn1 Edn1 Shisa7 Shisa7 Rasgrf1 Rasgrf1 Gper1 Gper1 Shisa8 Shisa8 LOC105993437 LOC105993437 Kcns1 Kcns1 Amigo1 Amigo1 LOC105997812 LOC105997812 Fkbp1b Fkbp1b Dysf Dysf Pirt Pirt Ehd3 Ehd3 ENSDORP00000027009 ENSDORP00000027009 Cav1 Cav1 Kcnj1 Kcnj1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mef2cMyocyte-specific enhancer factor 2C isoform X5. (483 aa)
Kcnc2Potassium voltage-gated channel subfamily C member 2 isoform X1; Belongs to the potassium channel family. (422 aa)
Pkd2Polycystin-2. (968 aa)
Kcne2Potassium voltage-gated channel subfamily E member 2. (123 aa)
Cacna2d1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1079 aa)
Rasgrf2Ras-specific guanine nucleotide-releasing factor 2. (1222 aa)
Kcne4LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily E member 4. (165 aa)
Cacnb2Voltage-dependent L-type calcium channel subunit beta-2 isoform X2. (580 aa)
CrhbpCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
Oprm1Mu-type opioid receptor isoform X3; Belongs to the G-protein coupled receptor 1 family. (391 aa)
Cnih2Protein cornichon homolog 2 isoform X2. (160 aa)
Pla2g685/88 kDa calcium-independent phospholipase A2. (802 aa)
R3hdm1R3H domain-containing protein 1 isoform X2. (384 aa)
Dapk1Death-associated protein kinase 1. (1430 aa)
Lrrc55Leucine-rich repeat-containing protein 55. (311 aa)
Ifngr1Interferon gamma receptor 1. (469 aa)
Vamp2Vesicle-associated membrane protein 2 isoform X2. (118 aa)
GemGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
Gnb5Guanine nucleotide-binding protein subunit beta-5. (395 aa)
Stac2SH3 and cysteine-rich domain-containing protein 2. (408 aa)
SelenonSelenoprotein N. (565 aa)
Nipsnap2Protein NipSnap homolog 2. (277 aa)
Fgf12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (241 aa)
Fam173aProtein FAM173A. (154 aa)
Kcnq1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (622 aa)
Rem2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
StacSH3 and cysteine-rich domain-containing protein isoform X1. (403 aa)
Cacng5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
Hap1Huntingtin-associated protein 1. (580 aa)
Cdk5Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
Hpcal1Hippocalcin-like protein 1. (193 aa)
Kcns2Potassium voltage-gated channel subfamily S member 2; Belongs to the potassium channel family. (478 aa)
Nlgn3Neuroligin-3 isoform X1. (848 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Kcng1Potassium voltage-gated channel subfamily G member 1; Belongs to the potassium channel family. (513 aa)
Nlgn2Neuroligin-2 isoform X1. (835 aa)
Fgf11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
StimateTransmembrane protein 110-like. (276 aa)
Homer1Homer protein homolog 1. (361 aa)
Abcc8ATP-binding cassette sub-family C member 8 isoform X1. (1582 aa)
Kif5bKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
Cfl1Cofilin-1; Belongs to the actin-binding proteins ADF family. (168 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
HpcaNeuron-specific calcium-binding protein hippocalcin. (193 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
Pde4bPhosphodiesterase. (659 aa)
Cacng2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (295 aa)
Kcnk3Potassium channel subfamily K member 3; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (416 aa)
Cacng4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CtssLOW QUALITY PROTEIN: cathepsin S; Belongs to the peptidase C1 family. (305 aa)
Neto2Neuropilin and tolloid-like protein 2. (518 aa)
Stac3SH3 and cysteine-rich domain-containing protein 3 isoform X1. (359 aa)
R3hdm2R3H domain-containing protein 2. (930 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1301 aa)
Akap6A-kinase anchor protein 6. (2320 aa)
Ephb2Ephrin type-B receptor 2 isoform X2. (1018 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Fmr1Fragile X mental retardation protein 1 isoform X1. (616 aa)
LOC106001740Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-like. (463 aa)
Kcna1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (496 aa)
Cacnb3Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (485 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta. (732 aa)
Prrt1Proline-rich transmembrane protein 1. (306 aa)
LOC105980465Peptidyl-prolyl cis-trans isomerase FKBP1A pseudogene. (88 aa)
Casq1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (408 aa)
Kcnc1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
Cacng3Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
Drd2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
RradGTP-binding protein RAD. (296 aa)
CrhCorticoliberin. (188 aa)
Lrrc52Leucine-rich repeat-containing protein 52. (315 aa)
CrbnProtein cereblon isoform X1. (442 aa)
NppaNatriuretic peptides A. (153 aa)
Snx27LOW QUALITY PROTEIN: sorting nexin-27. (380 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
Cabp2Calcium-binding protein 2. (192 aa)
Cabp4Calcium-binding protein 4. (271 aa)
EpoErythropoietin. (192 aa)
Mapk8ip2C-Jun-amino-terminal kinase-interacting protein 2. (804 aa)
Asic2Acid-sensing ion channel 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (512 aa)
Neto1Neuropilin and tolloid-like protein 1. (528 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
Actn2Alpha-actinin-2-like. (720 aa)
Hcn1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (831 aa)
Rgs9Regulator of G-protein signaling 9. (484 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (797 aa)
Cacnb1Voltage-dependent L-type calcium channel subunit beta-1. (677 aa)
Stim2Stromal interaction molecule 2. (566 aa)
Nedd4lE3 ubiquitin-protein ligase NEDD4-like isoform X1. (984 aa)
Shisa6Protein shisa-6 homolog. (455 aa)
Stoml1Stomatin-like protein 1. (352 aa)
Shank1SH3 and multiple ankyrin repeat domains protein 1. (1300 aa)
Abcc9ATP-binding cassette sub-family C member 9. (1521 aa)
P2ry6p2Y purinoceptor 6 isoform X3. (327 aa)
SriSorcin. (198 aa)
Rem1GTP-binding protein REM 1. (252 aa)
Cnih3Protein cornichon homolog 3. (152 aa)
HttHuntingtin. (3048 aa)
RelnReelin. (3415 aa)
Gpr35G-protein coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (303 aa)
ArcActivity-regulated cytoskeleton-associated protein. (396 aa)
CbarpProtein Dos. (713 aa)
Fkbp1aPeptidylprolyl isomerase. (108 aa)
Scn1bSodium channel subunit beta-1. (216 aa)
SlmapSarcolemmal membrane-associated protein isoform X5. (789 aa)
Casq2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (388 aa)
LOC106002211Small ubiquitin-related modifier. (89 aa)
Rnf207LOW QUALITY PROTEIN: RING finger protein 207. (475 aa)
Amigo3Amphoterin-induced protein 3. (434 aa)
Nlgn1Neuroligin-1 isoform X3. (843 aa)
Akap7A-kinase anchor protein 7 isoform gamma isoform X3. (81 aa)
Pink1Serine/threonine-protein kinase PINK1, mitochondrial. (577 aa)
Nrxn1Neurexin-1-beta isoform X1. (1515 aa)
Lrrc38Leucine-rich repeat-containing protein 38. (303 aa)
ENSDORP00000018748annotation not available (67 aa)
Kcne3Potassium voltage-gated channel subfamily E member 3. (107 aa)
PlnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
Slc6a9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (664 aa)
Gsg1lGerm cell-specific gene 1-like protein. (215 aa)
Crhr1Corticotropin-releasing factor receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (415 aa)
Cacnb4Voltage-dependent L-type calcium channel subunit beta-4. (333 aa)
Ank3Ankyrin-3 isoform X4. (1807 aa)
LOC106002162Disks large homolog 4-like. (150 aa)
Chrna4Neuronal acetylcholine receptor subunit alpha-4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (625 aa)
Klhl24Kelch-like protein 24 isoform X1. (600 aa)
S100a1Protein S100; Belongs to the S-100 family. (94 aa)
Pde4dPhosphodiesterase. (746 aa)
Mtnr1bMelatonin receptor type 1B; Belongs to the G-protein coupled receptor 1 family. (363 aa)
Cacng8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (415 aa)
ENSDORP00000020658annotation not available (108 aa)
Stim2-2Stromal interaction molecule 2. (85 aa)
Drd3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (445 aa)
Cabp5Calcium-binding protein 5. (170 aa)
DmdDystrophin isoform X3. (617 aa)
Jsrp1Junctional sarcoplasmic reticulum protein 1. (66 aa)
Ifngr2Interferon gamma receptor 2. (297 aa)
Cacna1aVoltage-dependent P/Q-type calcium channel subunit alpha-1A. (2254 aa)
Dlg4Disks large homolog 4; Belongs to the MAGUK family. (657 aa)
Rph3arabphilin-3A isoform X1. (672 aa)
HrcSarcoplasmic reticulum histidine-rich calcium-binding protein. (81 aa)
Trem2Triggering receptor expressed on myeloid cells 2. (251 aa)
Stim1Stromal interaction molecule 1 isoform X2. (685 aa)
Kcnab1Voltage-gated potassium channel subunit beta-1 isoform X3. (300 aa)
ENSDORP00000023261annotation not available (66 aa)
Kcne1Potassium voltage-gated channel subfamily E member 1. (150 aa)
Shank3SH3 and multiple ankyrin repeat domains protein 3. (1417 aa)
Cacng7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
Fgf13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
LOC105994343Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (224 aa)
Shisa9Protein shisa-9 isoform X1. (426 aa)
Mink1Misshapen-like kinase 1 isoform X6. (1343 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (247 aa)
StomErythrocyte band 7 integral membrane protein. (284 aa)
R3hdm1-2R3H domain-containing protein 1 isoform X6. (287 aa)
Ccr2C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (367 aa)
Sumo1Small ubiquitin-related modifier 1. (83 aa)
Edn1Endothelin-1-like isoform X1. (202 aa)
Shisa7Protein shisa-7. (380 aa)
Rasgrf1Ras-specific guanine nucleotide-releasing factor 1. (1234 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
Shisa8Uncharacterized protein. (212 aa)
LOC105993437LOW QUALITY PROTEIN: dystrophin-like. (776 aa)
Kcns1Potassium voltage-gated channel subfamily S member 1; Belongs to the potassium channel family. (527 aa)
Amigo1Amphoterin-induced protein 1. (493 aa)
LOC105997812LOW QUALITY PROTEIN: uncharacterized protein LOC105997812. (91 aa)
Fkbp1bPeptidylprolyl isomerase. (108 aa)
DysfDysferlin. (2084 aa)
PirtPhosphoinositide-interacting protein. (135 aa)
Ehd3EH domain-containing protein 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
ENSDORP00000027009annotation not available (80 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
Kcnj1ATP-sensitive inward rectifier potassium channel 1 isoform X3. (372 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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