(13 nodes) Clathrin adaptor complex network (Dipodomys ordii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ap2b1	AP complex subunit beta. (951 aa)
	Ap2a2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (916 aa)
	Lrrn2	LOW QUALITY PROTEIN: leucine-rich repeat neuronal protein 2. (712 aa)
	Lrrn3	Leucine-rich repeat neuronal protein 3. (708 aa)
	Slc18a3	Vesicular acetylcholine transporter. (532 aa)
	Clba1	Uncharacterized protein C14orf79 homolog. (278 aa)
	Ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (144 aa)
	Eps15	Epidermal growth factor receptor substrate 15. (880 aa)
	Ap2a1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
	Lrrn1	Leucine-rich repeat neuronal protein 1. (716 aa)
	Ap1g2	AP-1 complex subunit gamma. (786 aa)
	Ap1g1	AP-1 complex subunit gamma. (236 aa)
	Aftph	Aftiphilin isoform X1. (157 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aftph	Ap1g1	ENSDORP00000020361	ENSDORP00000018811	Aftiphilin isoform X1.	AP-1 complex subunit gamma.	0.408
Aftph	Ap1g2	ENSDORP00000020361	ENSDORP00000022066	Aftiphilin isoform X1.	AP-1 complex subunit gamma.	0.447
Ap1g1	Aftph	ENSDORP00000018811	ENSDORP00000020361	AP-1 complex subunit gamma.	Aftiphilin isoform X1.	0.408
Ap1g1	Ap1g2	ENSDORP00000018811	ENSDORP00000022066	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.902
Ap1g1	Ap2a1	ENSDORP00000018811	ENSDORP00000014053	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.483
Ap1g1	Ap2a2	ENSDORP00000018811	ENSDORP00000005395	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.448
Ap1g1	Ap2b1	ENSDORP00000018811	ENSDORP00000003551	AP-1 complex subunit gamma.	AP complex subunit beta.	0.987
Ap1g1	Ap2s1	ENSDORP00000018811	ENSDORP00000014383	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.953
Ap1g1	Eps15	ENSDORP00000018811	ENSDORP00000014180	AP-1 complex subunit gamma.	Epidermal growth factor receptor substrate 15.	0.662
Ap1g2	Aftph	ENSDORP00000022066	ENSDORP00000020361	AP-1 complex subunit gamma.	Aftiphilin isoform X1.	0.447
Ap1g2	Ap1g1	ENSDORP00000022066	ENSDORP00000018811	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.902
Ap1g2	Ap2a1	ENSDORP00000022066	ENSDORP00000014053	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.483
Ap1g2	Ap2a2	ENSDORP00000022066	ENSDORP00000005395	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.448
Ap1g2	Ap2b1	ENSDORP00000022066	ENSDORP00000003551	AP-1 complex subunit gamma.	AP complex subunit beta.	0.982
Ap1g2	Ap2s1	ENSDORP00000022066	ENSDORP00000014383	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.953
Ap1g2	Eps15	ENSDORP00000022066	ENSDORP00000014180	AP-1 complex subunit gamma.	Epidermal growth factor receptor substrate 15.	0.662
Ap2a1	Ap1g1	ENSDORP00000014053	ENSDORP00000018811	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP-1 complex subunit gamma.	0.483
Ap2a1	Ap1g2	ENSDORP00000014053	ENSDORP00000022066	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP-1 complex subunit gamma.	0.483
Ap2a1	Ap2a2	ENSDORP00000014053	ENSDORP00000005395	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.936
Ap2a1	Ap2b1	ENSDORP00000014053	ENSDORP00000003551	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP complex subunit beta.	0.995