(53 nodes) Preribosome network (Dipodomys ordii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Utp14a	U3 small nucleolar RNA-associated protein 14 homolog A. (773 aa)
	Riok1	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (570 aa)
	Nol6	Nucleolar protein 6. (1144 aa)
	Mphosph10	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (675 aa)
	Utp23	UTP23 small subunit processome component. (143 aa)
	Imp3	U3 small nucleolar ribonucleoprotein protein IMP3. (184 aa)
	Utp3	Something about silencing protein 10. (475 aa)
	Rsl24d1	Probable ribosome biogenesis protein RLP24. (153 aa)
	Noc2l	Nucleolar complex protein 2 homolog isoform X2. (718 aa)
	Nop56	Nucleolar protein 56. (261 aa)
	Utp20	Small subunit processome component 20 homolog. (2721 aa)
	Wdr12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (401 aa)
	Mak16	Protein MAK16 homolog; Belongs to the MAK16 family. (298 aa)
	Rrp7a	Ribosomal RNA-processing protein 7 homolog A. (279 aa)
	Riok2	Serine/threonine-protein kinase RIO2 isoform X1. (538 aa)
	Pes1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (601 aa)
	Wdr3	WD repeat-containing protein 3 isoform X2. (951 aa)
	Fam207a	Protein FAM207A. (172 aa)
	Wdr36	WD repeat-containing protein 36 isoform X1. (898 aa)
	Utp23-2	rRNA-processing protein UTP23 homolog. (259 aa)
	Utp6	U3 small nucleolar RNA-associated protein 6 homolog. (569 aa)
	ENSDORP00000021284	annotation not available (297 aa)
	Noc4l	Nucleolar complex protein 4 homolog. (518 aa)
	Fbl	rRNA 2'-O-methyltransferase fibrillarin. (308 aa)
	Prkdc	DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (4088 aa)
	Rrp15	RRP15-like protein. (273 aa)
	Pwp2	Periodic tryptophan protein 2 homolog. (897 aa)
	Bms1	Ribosome biogenesis protein BMS1 homolog isoform X1. (1276 aa)
	Rrp1	Ribosomal RNA processing protein 1 homolog A. (412 aa)
	Nol10	Nucleolar protein 10. (664 aa)
	Nop14	Nucleolar protein 14. (815 aa)
	Nob1	RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (408 aa)
	Nsa2	Ribosome biogenesis protein NSA2 homolog. (254 aa)
	ENSDORP00000021502	annotation not available (131 aa)
	ENSDORP00000021864	annotation not available (84 aa)
	Krr1	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (378 aa)
	ENSDORP00000022305	annotation not available (242 aa)
	Mrto4	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
	Hunk	Hormonally up-regulated neu tumor-associated kinase. (686 aa)
	Utp18	U3 small nucleolar RNA-associated protein 18 homolog. (464 aa)
	Nop9	Nucleolar protein 9. (639 aa)
	Rrp36	Ribosomal RNA processing protein 36 homolog. (229 aa)
	LOC105993916	U3 small nucleolar RNA-associated protein 14 homolog A-like. (735 aa)
	Pin4	Peptidyl-prolyl cis-trans isomerase. (131 aa)
	Bop1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (734 aa)
	ENSDORP00000024657	annotation not available (319 aa)
	Riok3	Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa)
	Imp4	U3 small nucleolar ribonucleoprotein protein IMP4. (291 aa)
	Cmss1	Protein CMSS1. (279 aa)
	Ltv1	Protein LTV1 homolog. (469 aa)
	Fcf1	rRNA-processing protein FCF1 homolog isoform X1. (193 aa)
	Emg1	EMG1 N1-specific pseudouridine methyltransferase. (232 aa)
	Rrp9	U3 small nucleolar RNA-interacting protein 2. (478 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bms1	Bop1	ENSDORP00000002802	ENSDORP00000024112	Ribosome biogenesis protein BMS1 homolog isoform X1.	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.935
Bms1	Cmss1	ENSDORP00000002802	ENSDORP00000009833	Ribosome biogenesis protein BMS1 homolog isoform X1.	Protein CMSS1.	0.603
Bms1	ENSDORP00000021284	ENSDORP00000002802	ENSDORP00000021284	Ribosome biogenesis protein BMS1 homolog isoform X1.	annotation not available	0.993
Bms1	ENSDORP00000021864	ENSDORP00000002802	ENSDORP00000021864	Ribosome biogenesis protein BMS1 homolog isoform X1.	annotation not available	0.673
Bms1	ENSDORP00000022305	ENSDORP00000002802	ENSDORP00000022305	Ribosome biogenesis protein BMS1 homolog isoform X1.	annotation not available	0.865
Bms1	ENSDORP00000024657	ENSDORP00000002802	ENSDORP00000024657	Ribosome biogenesis protein BMS1 homolog isoform X1.	annotation not available	0.992
Bms1	Emg1	ENSDORP00000002802	ENSDORP00000009206	Ribosome biogenesis protein BMS1 homolog isoform X1.	EMG1 N1-specific pseudouridine methyltransferase.	0.994
Bms1	Fbl	ENSDORP00000002802	ENSDORP00000005386	Ribosome biogenesis protein BMS1 homolog isoform X1.	rRNA 2'-O-methyltransferase fibrillarin.	0.997
Bms1	Fcf1	ENSDORP00000002802	ENSDORP00000009371	Ribosome biogenesis protein BMS1 homolog isoform X1.	rRNA-processing protein FCF1 homolog isoform X1.	0.997
Bms1	Imp3	ENSDORP00000002802	ENSDORP00000019218	Ribosome biogenesis protein BMS1 homolog isoform X1.	U3 small nucleolar ribonucleoprotein protein IMP3.	0.996
Bms1	Imp4	ENSDORP00000002802	ENSDORP00000010042	Ribosome biogenesis protein BMS1 homolog isoform X1.	U3 small nucleolar ribonucleoprotein protein IMP4.	0.998
Bms1	Krr1	ENSDORP00000002802	ENSDORP00000021869	Ribosome biogenesis protein BMS1 homolog isoform X1.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.992
Bms1	LOC105993916	ENSDORP00000002802	ENSDORP00000023767	Ribosome biogenesis protein BMS1 homolog isoform X1.	U3 small nucleolar RNA-associated protein 14 homolog A-like.	0.993
Bms1	Ltv1	ENSDORP00000002802	ENSDORP00000009652	Ribosome biogenesis protein BMS1 homolog isoform X1.	Protein LTV1 homolog.	0.937
Bms1	Mak16	ENSDORP00000002802	ENSDORP00000014792	Ribosome biogenesis protein BMS1 homolog isoform X1.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.865
Bms1	Mphosph10	ENSDORP00000002802	ENSDORP00000005625	Ribosome biogenesis protein BMS1 homolog isoform X1.	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.	0.999
Bms1	Mrto4	ENSDORP00000002802	ENSDORP00000022862	Ribosome biogenesis protein BMS1 homolog isoform X1.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.950
Bms1	Nob1	ENSDORP00000002802	ENSDORP00000000452	Ribosome biogenesis protein BMS1 homolog isoform X1.	RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.	0.942
Bms1	Noc2l	ENSDORP00000002802	ENSDORP00000012924	Ribosome biogenesis protein BMS1 homolog isoform X1.	Nucleolar complex protein 2 homolog isoform X2.	0.944
Bms1	Noc4l	ENSDORP00000002802	ENSDORP00000021289	Ribosome biogenesis protein BMS1 homolog isoform X1.	Nucleolar complex protein 4 homolog.	0.996