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Atp2b1 Atp2b1 Kcnma1 Kcnma1 Chrnb2 Chrnb2 Slc6a9 Slc6a9 Nrxn1 Nrxn1 Lpar2 Lpar2 Pip5k1c Pip5k1c Syt11 Syt11 Kcna4 Kcna4 Chrm1 Chrm1 Erc2 Erc2 Grik5 Grik5 Htr1a Htr1a Marcksl1 Marcksl1 Fer1l4 Fer1l4 ENSDORP00000016518 ENSDORP00000016518 Snph Snph P2rx3 P2rx3 Lrfn3 Lrfn3 Slc6a11 Slc6a11 Slc6a1 Slc6a1 Scn8a Scn8a Ncam1 Ncam1 P2ry2 P2ry2 Adgrl1 Adgrl1 Atp2b4 Atp2b4 L1cam L1cam Sept3 Sept3 Stxbp1 Stxbp1 Cask Cask Otof Otof Atp2b3 Atp2b3 Erbb4 Erbb4 Fmr1 Fmr1 Fer1l6 Fer1l6 Ephb2 Ephb2 Gpm6a Gpm6a Aph1a Aph1a Slc6a5 Slc6a5 Grin2a Grin2a Efnb2 Efnb2 Stx1b Stx1b Fxyd6 Fxyd6 Hip1 Hip1 Cntnap4 Cntnap4 Grik1 Grik1 Fosl1 Fosl1 Slc1a7 Slc1a7 Grik4 Grik4 Cltb Cltb Cyth1 Cyth1 Cnr1 Cnr1 Cadm3 Cadm3 Cdh10 Cdh10 Exoc3 Exoc3 Chrm2 Chrm2 Slc6a7 Slc6a7 Kcnc2 Kcnc2 Nectin1 Nectin1 Grm2 Grm2 Stx1a Stx1a Cacna2d1 Cacna2d1 Cacna1e Cacna1e Gabbr2 Gabbr2 Psen2 Psen2 Gria1 Gria1 Kctd12 Kctd12 Cdh9 Cdh9 P2rx1 P2rx1 Scn10a Scn10a Apba1 Apba1 Ncstn Ncstn Scn1a Scn1a Gria3 Gria3 Grm3 Grm3 Slc1a6 Slc1a6 Kcna3 Kcna3 Kcna2 Kcna2 Gria2 Gria2 Epha4 Epha4 Clta Clta Snap91 Snap91 Ache Ache Kcnh1 Kcnh1 Cntn6 Cntn6 Kcnc4 Kcnc4 Ntng1 Ntng1 Dgki Dgki Grm8 Grm8 Ptprs Ptprs Adcy8 Adcy8 Kctd16 Kctd16 ENSDORP00000027334 ENSDORP00000027334 Gabra5 Gabra5 Pcdh17 Pcdh17 Chrna7 Chrna7 Cadm1 Cadm1 Cplx3 Cplx3 Efnb1 Efnb1 Ntng2 Ntng2 Slc6a3 Slc6a3 Kcnc3 Kcnc3 Efnb3 Efnb3 Prrt2 Prrt2 Glra1 Glra1 Pcdh19 Pcdh19 Snap91-2 Snap91-2 Syt7 Syt7 Gpc4 Gpc4 Grin1 Grin1 Chrm4 Chrm4 Chrna6 Chrna6 Atp2b2 Atp2b2 Cacna1h Cacna1h Cacna1a Cacna1a Cadps2 Cadps2 Grm7 Grm7 Ptprd Ptprd Dnm1 Dnm1 Kcnj3 Kcnj3 Kcnj9 Kcnj9 Canx Canx Slc1a2 Slc1a2 Adam23 Adam23
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Atp2b1Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1019 aa)
Kcnma1Calcium-activated potassium channel subunit alpha-1. (1132 aa)
Chrnb2Neuronal acetylcholine receptor subunit beta-2 isoform X1. (504 aa)
Slc6a9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (664 aa)
Nrxn1Neurexin-1-beta isoform X1. (1515 aa)
Lpar2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (349 aa)
Pip5k1cLOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (976 aa)
Syt11Synaptotagmin-11. (431 aa)
Kcna4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (653 aa)
Chrm1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
Erc2ERC protein 2. (969 aa)
Grik5Glutamate receptor ionotropic, kainate 5. (985 aa)
Htr1a5-hydroxytryptamine receptor 1A. (422 aa)
Marcksl1MARCKS-related protein. (200 aa)
Fer1l4Fer-1-like protein 4. (2008 aa)
ENSDORP00000016518annotation not available (92 aa)
SnphSyntaphilin. (495 aa)
P2rx3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
Lrfn3Leucine-rich repeat and fibronectin type-III domain-containing protein 3. (522 aa)
Slc6a11Sodium- and chloride-dependent GABA transporter 3. (590 aa)
Slc6a1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
Scn8aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1982 aa)
Ncam1Neural cell adhesion molecule 1. (848 aa)
P2ry2p2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
Adgrl1Latrophilin-1; Belongs to the G-protein coupled receptor 2 family. (1041 aa)
Atp2b4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1230 aa)
L1camNeural cell adhesion molecule L1 isoform X1. (1260 aa)
Sept3Neuronal-specific septin-3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (345 aa)
Stxbp1Syntaxin-binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
CaskPeripheral plasma membrane protein CASK isoform X1; Belongs to the MAGUK family. (927 aa)
OtofOtoferlin isoform X1. (1998 aa)
Atp2b3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1085 aa)
Erbb4Receptor protein-tyrosine kinase. (1308 aa)
Fmr1Fragile X mental retardation protein 1 isoform X1. (616 aa)
Fer1l6Fer-1-like protein 6. (1863 aa)
Ephb2Ephrin type-B receptor 2 isoform X2. (1018 aa)
Gpm6aNeuronal membrane glycoprotein M6-a. (278 aa)
Aph1aGamma-secretase subunit APH-1A. (265 aa)
Slc6a5Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (806 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1301 aa)
Efnb2ephrin-B2; Belongs to the ephrin family. (325 aa)
Stx1bsyntaxin-1B; Belongs to the syntaxin family. (286 aa)
Fxyd6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa)
Hip1Huntingtin-interacting protein 1. (1029 aa)
Cntnap4Contactin-associated protein-like 4 isoform X1. (1310 aa)
Grik1Glutamate receptor ionotropic, kainate 1 isoform X1. (926 aa)
Fosl1Fos-related antigen 1 isoform X1. (278 aa)
Slc1a7Amino acid transporter. (558 aa)
Grik4Glutamate receptor ionotropic, kainate 4. (765 aa)
CltbClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (179 aa)
Cyth1Cytohesin-1. (396 aa)
Cnr1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (471 aa)
Cadm3Cell adhesion molecule 3 isoform X2. (396 aa)
Cdh10Cadherin-10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
Exoc3Exocyst complex component 3. (755 aa)
Chrm2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
Slc6a7Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (625 aa)
Kcnc2Potassium voltage-gated channel subfamily C member 2 isoform X1; Belongs to the potassium channel family. (422 aa)
Nectin1Nectin-1. (505 aa)
Grm2Metabotropic glutamate receptor 2. (872 aa)
Stx1asyntaxin-1A; Belongs to the syntaxin family. (288 aa)
Cacna2d1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1079 aa)
Cacna1eVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2325 aa)
Gabbr2Gamma-aminobutyric acid type B receptor subunit 2. (954 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
Gria1Glutamate receptor 1 isoform X2. (906 aa)
Kctd12BTB/POZ domain-containing protein KCTD12. (327 aa)
Cdh9Cadherin-9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
P2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
Scn10aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1937 aa)
Apba1Amyloid beta A4 precursor protein-binding family A member 1. (808 aa)
NcstnNicastrin. (698 aa)
Scn1aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1998 aa)
Gria3Glutamate receptor 3 isoform X2. (894 aa)
Grm3Metabotropic glutamate receptor 3. (882 aa)
Slc1a6Amino acid transporter. (544 aa)
Kcna3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (509 aa)
Kcna2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
Gria2Glutamate receptor 2. (842 aa)
Epha4Ephrin type-A receptor 4 isoform X1. (986 aa)
CltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
Snap91Clathrin coat assembly protein AP180 isoform X1. (596 aa)
AcheCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (614 aa)
Kcnh1Potassium voltage-gated channel subfamily H member 1 isoform X1. (990 aa)
Cntn6Contactin-6. (1028 aa)
Kcnc4Potassium voltage-gated channel subfamily C member 4 isoform X2; Belongs to the potassium channel family. (630 aa)
Ntng1netrin-G1 isoform X1. (543 aa)
DgkiDiacylglycerol kinase. (901 aa)
Grm8Metabotropic glutamate receptor 8 isoform X1. (908 aa)
PtprsReceptor-type tyrosine-protein phosphatase S. (1430 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
Kctd16BTB/POZ domain-containing protein KCTD16. (428 aa)
ENSDORP00000027334annotation not available (103 aa)
Gabra5Gamma-aminobutyric acid receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
Pcdh17Protocadherin-17. (1162 aa)
Chrna7Neuronal acetylcholine receptor subunit alpha-7. (568 aa)
Cadm1Cell adhesion molecule 1 isoform X1. (474 aa)
Cplx3Complexin-3. (158 aa)
Efnb1ephrin-B1; Belongs to the ephrin family. (345 aa)
Ntng2netrin-G2. (529 aa)
Slc6a3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (635 aa)
Kcnc3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (709 aa)
Efnb3ephrin-B3; Belongs to the ephrin family. (340 aa)
Prrt2Proline-rich transmembrane protein 2. (61 aa)
Glra1Glycine receptor subunit alpha-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
Pcdh19Protocadherin-19 isoform X1. (1148 aa)
Snap91-2Clathrin coat assembly protein AP180 isoform X3. (120 aa)
Syt7Synaptotagmin 7. (556 aa)
Gpc4Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
Chrm4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa)
Chrna6Neuronal acetylcholine receptor subunit alpha-6. (494 aa)
Atp2b2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
Cacna1hVoltage-dependent T-type calcium channel subunit alpha-1H. (2166 aa)
Cacna1aVoltage-dependent P/Q-type calcium channel subunit alpha-1A. (2254 aa)
Cadps2Calcium-dependent secretion activator 2. (1249 aa)
Grm7Metabotropic glutamate receptor 7 isoform X1. (918 aa)
PtprdReceptor-type tyrosine-protein phosphatase delta isoform X3. (1912 aa)
Dnm1Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
Kcnj3G protein-activated inward rectifier potassium channel 1 isoform X1. (502 aa)
Kcnj9G protein-activated inward rectifier potassium channel 3. (393 aa)
CanxCalnexin. (560 aa)
Slc1a2Amino acid transporter. (573 aa)
Adam23Disintegrin and metalloproteinase domain-containing protein 23. (820 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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