(76 nodes) Tyrosine-specific protein phosphatases domain network (Dipodomys ordii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
	Ptprg	Receptor-type tyrosine-protein phosphatase gamma isoform X2. (667 aa)
	Dusp7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
	Ptprs	Receptor-type tyrosine-protein phosphatase S. (1430 aa)
	Cdc14b	Dual specificity protein phosphatase CDC14B. (470 aa)
	Ptprf	Receptor-type tyrosine-protein phosphatase F isoform X1. (1901 aa)
	Ptpn5	Tyrosine-protein phosphatase non-receptor type 5 isoform X1. (369 aa)
	Dnajc6	Putative tyrosine-protein phosphatase auxilin. (931 aa)
	Dusp27	Inactive dual specificity phosphatase 27; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (1144 aa)
	Dusp18	Dual specificity protein phosphatase 18; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (188 aa)
	Dusp5	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
	Tns3	Tensin-3 isoform X1. (1444 aa)
	Ptpru	Receptor-type tyrosine-protein phosphatase U. (1445 aa)
	Mtmr4	Myotubularin-related protein 4 isoform X1. (204 aa)
	Dusp12	Dual specificity protein phosphatase 12. (338 aa)
	Cdkn3	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (176 aa)
	Ptpdc1	Protein tyrosine phosphatase domain-containing protein 1 isoform X1. (748 aa)
	Ptpn6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	Mtmr2	Myotubularin-related protein 2 isoform X1. (643 aa)
	Ptprr	Receptor-type tyrosine-protein phosphatase R isoform X2. (411 aa)
	Ssh1	Protein phosphatase Slingshot homolog 1. (1010 aa)
	Ptpn3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (334 aa)
	Epm2a	Laforin. (230 aa)
	Ptpmt1	Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1. (209 aa)
	Dusp19	Dual specificity protein phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (221 aa)
	Ptprq	Phosphatidylinositol phosphatase PTPRQ. (2323 aa)
	Dusp26	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa)
	Mtm1	Myotubularin isoform X1. (603 aa)
	Ptprj	Receptor-type tyrosine-protein phosphatase eta. (1205 aa)
	Ptp4a1	Protein tyrosine phosphatase type IVA 1. (173 aa)
	Ptpra	Receptor-type tyrosine-protein phosphatase alpha. (789 aa)
	Ptprt	Receptor-type tyrosine-protein phosphatase T isoform X2. (1441 aa)
	Ptpn1	Tyrosine-protein phosphatase non-receptor type. (436 aa)
	Dusp6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
	Ptpn2	Tyrosine-protein phosphatase non-receptor type 2. (397 aa)
	Dusp3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
	Cdc14a	Dual specificity protein phosphatase CDC14A isoform X1. (611 aa)
	Ptprk	Receptor-type tyrosine-protein phosphatase kappa isoform X1. (1457 aa)
	Dusp22	Dual specificity protein phosphatase 22 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa)
	Ptprb	Receptor-type tyrosine-protein phosphatase beta isoform X2. (1999 aa)
	Ptprd	Receptor-type tyrosine-protein phosphatase delta isoform X3. (1912 aa)
	Ptpn22	Tyrosine-protein phosphatase non-receptor type 22 isoform X6. (135 aa)
	LOC105990085	Tyrosine-protein phosphatase non-receptor type. (333 aa)
	Dusp9	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	Dusp15	Dual specificity protein phosphatase 15; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (145 aa)
	Styx	Serine/threonine/tyrosine-interacting protein. (223 aa)
	Ptp4a2	Protein tyrosine phosphatase type IVA 2. (167 aa)
	Ptpn21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (336 aa)
	Dusp13	Dual specificity protein phosphatase 13 isoform B-like; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (239 aa)
	Ssh3	Protein phosphatase Slingshot homolog 3. (645 aa)
	Ptpre	Receptor-type tyrosine-protein phosphatase epsilon. (701 aa)
	Dusp14	Dual specificity protein phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (198 aa)
	Dupd1	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (215 aa)
	Dusp4	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (395 aa)
	Dusp23	Dual specificity protein phosphatase 23. (150 aa)
	Mtmr7	Myotubularin-related protein 7. (499 aa)
	Ptpn12	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (387 aa)
	Ptprn	Receptor-type tyrosine-protein phosphatase-like N isoform X1. (977 aa)
	Dusp1	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (244 aa)
	Ssh2	Protein phosphatase Slingshot homolog 2. (216 aa)
	Ptpn14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (847 aa)
	Ptprc	Receptor-type tyrosine-protein phosphatase C isoform X1. (1252 aa)
	Ptp4a3	Protein tyrosine phosphatase type IVA 3. (173 aa)
	Ptprm	Receptor-type tyrosine-protein phosphatase mu. (1452 aa)
	Dusp11	RNA/RNP complex-1-interacting phosphatase. (328 aa)
	Dusp2	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (318 aa)
	Rngtt	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
	Dusp10	Dual specificity protein phosphatase 10. (482 aa)
	Mtmr1	Myotubularin-related protein 1. (687 aa)
	Ptpn9	Tyrosine-protein phosphatase non-receptor type 9. (572 aa)
	Ptpn18	Tyrosine-protein phosphatase non-receptor type 18 isoform X1. (455 aa)
	Ptpn7	LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 7. (354 aa)
	Ptprz1	Receptor-type tyrosine-protein phosphatase zeta. (2286 aa)
	Ptpn13	Tyrosine-protein phosphatase non-receptor type 13. (2409 aa)
	Styxl1	Serine/threonine/tyrosine-interacting-like protein 1. (298 aa)
	Pten	Phosphatase and tensin homolog. (396 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdc14a	Cdc14b	ENSDORP00000023130	ENSDORP00000005620	Dual specificity protein phosphatase CDC14A isoform X1.	Dual specificity protein phosphatase CDC14B.	0.854
Cdc14b	Cdc14a	ENSDORP00000005620	ENSDORP00000023130	Dual specificity protein phosphatase CDC14B.	Dual specificity protein phosphatase CDC14A isoform X1.	0.854
Cdkn3	Dupd1	ENSDORP00000001392	ENSDORP00000017812	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.403
Dnajc6	Pten	ENSDORP00000005323	ENSDORP00000008384	Putative tyrosine-protein phosphatase auxilin.	Phosphatase and tensin homolog.	0.445
Dnajc6	Tns3	ENSDORP00000005323	ENSDORP00000002917	Putative tyrosine-protein phosphatase auxilin.	Tensin-3 isoform X1.	0.471
Dupd1	Cdkn3	ENSDORP00000017812	ENSDORP00000001392	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.	0.403
Dupd1	Ptpn5	ENSDORP00000017812	ENSDORP00000005342	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase non-receptor type 5 isoform X1.	0.631
Dupd1	Ptpn7	ENSDORP00000017812	ENSDORP00000009852	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 7.	0.574
Dupd1	Ptprq	ENSDORP00000017812	ENSDORP00000027630	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Phosphatidylinositol phosphatase PTPRQ.	0.478
Dupd1	Ptprr	ENSDORP00000017812	ENSDORP00000000868	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Receptor-type tyrosine-protein phosphatase R isoform X2.	0.574
Dusp1	Dusp6	ENSDORP00000016445	ENSDORP00000024627	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.446
Dusp1	Dusp7	ENSDORP00000016445	ENSDORP00000006032	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.446
Dusp1	Dusp9	ENSDORP00000016445	ENSDORP00000020749	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.442
Dusp1	Ptpn5	ENSDORP00000016445	ENSDORP00000005342	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase non-receptor type 5 isoform X1.	0.493
Dusp1	Ptpn7	ENSDORP00000016445	ENSDORP00000009852	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 7.	0.452
Dusp1	Ptprq	ENSDORP00000016445	ENSDORP00000027630	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Phosphatidylinositol phosphatase PTPRQ.	0.478
Dusp1	Ptprr	ENSDORP00000016445	ENSDORP00000000868	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Receptor-type tyrosine-protein phosphatase R isoform X2.	0.520
Dusp10	Dusp6	ENSDORP00000010253	ENSDORP00000024627	Dual specificity protein phosphatase 10.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.560
Dusp10	Dusp7	ENSDORP00000010253	ENSDORP00000006032	Dual specificity protein phosphatase 10.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.564
Dusp10	Dusp9	ENSDORP00000010253	ENSDORP00000020749	Dual specificity protein phosphatase 10.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.571