STRINGSTRING
Sh3bp2 Sh3bp2 Socs1 Socs1 Frk Frk Crk Crk Stap1 Stap1 Bmx Bmx Socs7 Socs7 Socs2 Socs2 Rin3-2 Rin3-2 Stat3 Stat3 Hck Hck Bcar3 Bcar3 Btk Btk Grb7 Grb7 Sh2d7 Sh2d7 Sh2b1 Sh2b1 Matk Matk Sh2d1a Sh2d1a Blnk Blnk Sh2d3c Sh2d3c Grb2 Grb2 Socs3 Socs3 Lck Lck Stat5a Stat5a Rin2 Rin2 Syk Syk Lyn Lyn Ptpn6 Ptpn6 Socs4 Socs4 Rasa1 Rasa1 Shc2 Shc2 Vav3 Vav3 Yes1 Yes1 Tns3 Tns3 Nck2 Nck2 Shc1 Shc1 Shb Shb Chn2 Chn2 Ptk6 Ptk6 Grap Grap Shc3 Shc3 Sh2b2 Sh2b2 Shd Shd Blk Blk Zap70 Zap70 Sh2d5 Sh2d5 Sla Sla Rin1 Rin1 Ptpn11 Ptpn11 Sla2 Sla2 Supt6h Supt6h Sh2d4a Sh2d4a Tyk2 Tyk2 Cblb Cblb Shc4 Shc4 Itk Itk Stat1 Stat1 Inppl1 Inppl1 Vav2 Vav2 Fer Fer Socs6 Socs6 Plcg1 Plcg1 Stap2 Stap2 Abl2 Abl2 Stat6 Stat6 Jak3 Jak3 Stat2 Stat2 Csk Csk Jak1 Jak1 Nck1 Nck1 Tns2 Tns2 Fgr Fgr Shf Shf Inpp5d Inpp5d Grap2 Grap2 Dapp1 Dapp1 Grb10 Grb10 Plcg2 Plcg2 Tns4 Tns4 Src Src Lcp2 Lcp2 Fyn Fyn Tec Tec Clnk Clnk Pik3r3 Pik3r3 Tns1 Tns1 Cish Cish Jak2 Jak2 Grb14 Grb14 She She Pik3r1 Pik3r1 Sh2d2a Sh2d2a Cbl Cbl Socs5 Socs5 Vav1 Vav1 Stat4 Stat4 Crkl Crkl Txk Txk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sh3bp2SH3 domain-binding protein 2 isoform X1. (580 aa)
Socs1Suppressor of cytokine signaling 1. (177 aa)
FrkTyrosine-protein kinase. (514 aa)
CrkAdapter molecule crk. (304 aa)
Stap1Signal-transducing adaptor protein 1 isoform X1. (301 aa)
BmxTyrosine-protein kinase. (623 aa)
Socs7Suppressor of cytokine signaling 7. (580 aa)
Socs2Suppressor of cytokine signaling 2. (198 aa)
Rin3-2Ras and Rab interactor 3. (235 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
HckTyrosine-protein kinase. (526 aa)
Bcar3Breast cancer anti-estrogen resistance protein 3. (798 aa)
BtkTyrosine-protein kinase. (659 aa)
Grb7Growth factor receptor-bound protein 7. (531 aa)
Sh2d7SH2 domain-containing protein 7. (260 aa)
Sh2b1SH2B adapter protein 1 isoform X3. (726 aa)
MatkTyrosine-protein kinase. (484 aa)
Sh2d1aSH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (126 aa)
BlnkB-cell linker protein. (427 aa)
Sh2d3cSH2 domain-containing protein 3C isoform X1. (857 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Socs3Suppressor of cytokine signaling 3. (228 aa)
LckTyrosine-protein kinase. (509 aa)
Stat5aSignal transducer and activator of transcription. (793 aa)
Rin2Ras and Rab interactor 2 isoform X1. (463 aa)
SykTyrosine-protein kinase. (633 aa)
LynTyrosine-protein kinase. (512 aa)
Ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
Socs4Suppressor of cytokine signaling 4. (441 aa)
Rasa1Ras GTPase-activating protein 1. (813 aa)
Shc2SHC-transforming protein 2. (513 aa)
Vav3Guanine nucleotide exchange factor VAV3. (847 aa)
Yes1Tyrosine-protein kinase. (541 aa)
Tns3Tensin-3 isoform X1. (1444 aa)
Nck2Cytoplasmic protein. (380 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
ShbSH2 domain-containing adapter protein B. (509 aa)
Chn2Chimaerin; GTPase-activating protein for p21-rac. (468 aa)
Ptk6Tyrosine-protein kinase. (451 aa)
GrapGRB2-related adapter protein isoform X1. (217 aa)
Shc3SHC-transforming protein 3. (598 aa)
Sh2b2SH2B adapter protein 2. (436 aa)
ShdSH2 domain-containing adapter protein D. (313 aa)
BlkTyrosine-protein kinase. (497 aa)
Zap70Tyrosine-protein kinase. (618 aa)
Sh2d5SH2 domain-containing protein 5. (430 aa)
SlaSrc-like-adapter isoform X1. (292 aa)
Rin1Ras and Rab interactor 1. (785 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Sla2Src-like-adapter 2. (262 aa)
Supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (658 aa)
Sh2d4aSH2 domain-containing protein 4A. (375 aa)
Tyk2Tyrosine-protein kinase. (1053 aa)
CblbE3 ubiquitin-protein ligase CBL-B isoform X2. (939 aa)
Shc4SHC-transforming protein 4. (340 aa)
ItkTyrosine-protein kinase. (620 aa)
Stat1Signal transducer and activator of transcription. (765 aa)
Inppl1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1240 aa)
Vav2Guanine nucleotide exchange factor VAV2. (766 aa)
FerTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (775 aa)
Socs6Suppressor of cytokine signaling 6. (535 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Stap2Signal-transducing adaptor protein 2. (411 aa)
Abl2Tyrosine-protein kinase. (1132 aa)
Stat6Signal transducer and activator of transcription. (834 aa)
Jak3Tyrosine-protein kinase JAK3. (999 aa)
Stat2Signal transducer and activator of transcription. (752 aa)
CskTyrosine-protein kinase. (450 aa)
Jak1Tyrosine-protein kinase. (1155 aa)
Nck1Cytoplasmic protein. (377 aa)
Tns2Tensin-2 isoform X1. (1411 aa)
FgrTyrosine-protein kinase. (527 aa)
ShfSH2 domain-containing adapter protein F. (239 aa)
Inpp5dPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1186 aa)
Grap2GRB2-related adapter protein 2 isoform X2. (324 aa)
Dapp1Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X1. (280 aa)
Grb10Growth factor receptor-bound protein 10 isoform X2. (541 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
Tns4Tensin-4. (664 aa)
SrcTyrosine-protein kinase. (539 aa)
Lcp2Lymphocyte cytosolic protein 2. (314 aa)
FynTyrosine-protein kinase. (518 aa)
TecTyrosine-protein kinase. (631 aa)
ClnkCytokine-dependent hematopoietic cell linker. (370 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Tns1Tensin-1 isoform X3. (1790 aa)
CishCytokine-inducible SH2-containing protein. (255 aa)
Jak2Tyrosine-protein kinase. (1037 aa)
Grb14Growth factor receptor-bound protein 14. (507 aa)
SheSH2 domain-containing adapter protein E. (504 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Sh2d2aSH2 domain-containing protein 2A isoform X1. (367 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
Socs5Suppressor of cytokine signaling 5. (536 aa)
Vav1Proto-oncogene vav. (845 aa)
Stat4Signal transducer and activator of transcription. (748 aa)
CrklCrk-like protein. (303 aa)
TxkTyrosine-protein kinase. (527 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.