12 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Src	Tyrosine-protein kinase. (539 aa)
	Fyn	Tyrosine-protein kinase. (518 aa)
	Kitl	Kit ligand. (231 aa)
	Ptpn6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	Fndc3a	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	Lyn	Tyrosine-protein kinase. (512 aa)
	Sos1	Son of sevenless homolog 1. (1301 aa)
	Yes1	Tyrosine-protein kinase. (541 aa)
	Sh2b2	SH2B adapter protein 2. (436 aa)
	Kit	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
	Grb2	Growth factor receptor-bound protein 2. (217 aa)
	Cbl	E3 ubiquitin-protein ligase CBL. (51 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cbl	Fyn	ENSDORP00000020259	ENSDORP00000015716	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.750
Cbl	Grb2	ENSDORP00000020259	ENSDORP00000027785	E3 ubiquitin-protein ligase CBL.	Growth factor receptor-bound protein 2.	0.994
Cbl	Kit	ENSDORP00000020259	ENSDORP00000006862	E3 ubiquitin-protein ligase CBL.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.904
Cbl	Kitl	ENSDORP00000020259	ENSDORP00000019655	E3 ubiquitin-protein ligase CBL.	Kit ligand.	0.610
Cbl	Lyn	ENSDORP00000020259	ENSDORP00000000698	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.975
Cbl	Ptpn6	ENSDORP00000020259	ENSDORP00000001109	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.703
Cbl	Sh2b2	ENSDORP00000020259	ENSDORP00000005552	E3 ubiquitin-protein ligase CBL.	SH2B adapter protein 2.	0.927
Cbl	Sos1	ENSDORP00000020259	ENSDORP00000002200	E3 ubiquitin-protein ligase CBL.	Son of sevenless homolog 1.	0.723
Cbl	Src	ENSDORP00000020259	ENSDORP00000015316	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.927
Cbl	Yes1	ENSDORP00000020259	ENSDORP00000002444	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.927
Fndc3a	Ptpn6	ENSDORP00000000360	ENSDORP00000001109	Fibronectin type-III domain-containing protein 3A isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.546
Fyn	Cbl	ENSDORP00000015716	ENSDORP00000020259	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase CBL.	0.750
Fyn	Grb2	ENSDORP00000015716	ENSDORP00000027785	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.771
Fyn	Kit	ENSDORP00000015716	ENSDORP00000006862	Tyrosine-protein kinase.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.610
Fyn	Kitl	ENSDORP00000015716	ENSDORP00000019655	Tyrosine-protein kinase.	Kit ligand.	0.449
Fyn	Ptpn6	ENSDORP00000015716	ENSDORP00000001109	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.666
Fyn	Sh2b2	ENSDORP00000015716	ENSDORP00000005552	Tyrosine-protein kinase.	SH2B adapter protein 2.	0.575
Fyn	Sos1	ENSDORP00000015716	ENSDORP00000002200	Tyrosine-protein kinase.	Son of sevenless homolog 1.	0.656
Grb2	Cbl	ENSDORP00000027785	ENSDORP00000020259	Growth factor receptor-bound protein 2.	E3 ubiquitin-protein ligase CBL.	0.994
Grb2	Fyn	ENSDORP00000027785	ENSDORP00000015716	Growth factor receptor-bound protein 2.	Tyrosine-protein kinase.	0.771