STRINGSTRING
Eps15l1 Eps15l1 Fndc3a Fndc3a Egf Egf Sh3gl2 Sh3gl2 Ptpn3 Ptpn3 Rnf222 Rnf222 Sos1 Sos1 Shc1 Shc1 Areg Areg Rps27a Rps27a Ptpn11 Ptpn11 Stam Stam Ereg Ereg Pik3ca Pik3ca Lrig3 Lrig3 Kras-2 Kras-2 Csde1 Csde1 Tgfb1i1 Tgfb1i1 Plcg1 Plcg1 Sh3gl1 Sh3gl1 Hbegf Hbegf Csk Csk Egfr Egfr Epgn Epgn Sh3gl3 Sh3gl3 Eps15 Eps15 Ptprm Ptprm Gab1 Gab1 Aamp Aamp Btc Btc Lpxn Lpxn Stam2 Stam2 Lrig1 Lrig1 ENSDORP00000019733 ENSDORP00000019733 Pik3r1 Pik3r1 Cbl Cbl LOC105993014 LOC105993014 Kras Kras Tgfa Tgfa Hgs Hgs Spry2 Spry2 Uba52 Uba52 LOC105986631 LOC105986631 Nras Nras LOC105989352 LOC105989352 Ptprk Ptprk Pag1 Pag1 Pxn Pxn Spry1 Spry1 Ptprt Ptprt Sh3kbp1 Sh3kbp1 Lrig2 Lrig2 Hras Hras Arhgef7 Arhgef7 Grb2 Grb2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Eps15l1Epidermal growth factor receptor substrate 15-like 1. (678 aa)
Fndc3aFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (664 aa)
Sh3gl2endophilin-A1. (346 aa)
Ptpn3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (334 aa)
Rnf222RING finger protein 222. (211 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
AregAmphiregulin. (245 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
StamSignal transducing adapter molecule 1. (538 aa)
EregProepiregulin. (163 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Lrig3Leucine-rich repeats and immunoglobulin-like domains protein 3. (1118 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Tgfb1i1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (462 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Sh3gl1endophilin-A2. (367 aa)
HbegfProheparin-binding EGF-like growth factor. (206 aa)
CskTyrosine-protein kinase. (450 aa)
EgfrReceptor protein-tyrosine kinase. (1215 aa)
EpgnEpigen isoform X5. (153 aa)
Sh3gl3endophilin-A3. (346 aa)
Eps15Epidermal growth factor receptor substrate 15. (880 aa)
PtprmReceptor-type tyrosine-protein phosphatase mu. (1452 aa)
Gab1GRB2-associated-binding protein 1. (707 aa)
AampAngio-associated migratory cell protein. (435 aa)
BtcProbetacellulin. (163 aa)
LpxnLeupaxin; Belongs to the paxillin family. (386 aa)
Stam2Signal transducing adapter molecule 2 isoform X1. (521 aa)
Lrig1Leucine-rich repeats and immunoglobulin-like domains protein 1. (1035 aa)
ENSDORP00000019733annotation not available (100 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
LOC105993014ubiquitin-40S ribosomal protein S27a pseudogene. (147 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
TgfaProtransforming growth factor alpha. (156 aa)
HgsHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (775 aa)
Spry2Protein sprouty homolog 2. (315 aa)
Uba52ubiquitin-60S ribosomal protein L40. (128 aa)
LOC105986631Ubiquitin-like. (77 aa)
NrasGTPase NRas. (189 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
PtprkReceptor-type tyrosine-protein phosphatase kappa isoform X1. (1457 aa)
Pag1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (433 aa)
PxnPaxillin isoform X3; Belongs to the paxillin family. (547 aa)
Spry1Protein sprouty homolog 1. (317 aa)
PtprtReceptor-type tyrosine-protein phosphatase T isoform X2. (1441 aa)
Sh3kbp1SH3 domain-containing kinase-binding protein 1 isoform X5. (707 aa)
Lrig2Leucine-rich repeats and immunoglobulin-like domains protein 2. (915 aa)
HrasGTPase HRas isoform X1. (192 aa)
Arhgef7Rho guanine nucleotide exchange factor 7. (820 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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