16 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Btc	Probetacellulin. (163 aa)
	Epgn	Epigen isoform X5. (153 aa)
	Egfr	Receptor protein-tyrosine kinase. (1215 aa)
	Hbegf	Proheparin-binding EGF-like growth factor. (206 aa)
	Csde1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	Kras-2	GTPase KRas isoform X4. (189 aa)
	Ereg	Proepiregulin. (163 aa)
	Grb2	Growth factor receptor-bound protein 2. (217 aa)
	Areg	Amphiregulin. (245 aa)
	Egf	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (664 aa)
	Shc1	SHC-transforming protein 1 isoform X2. (473 aa)
	Sos1	Son of sevenless homolog 1. (1301 aa)
	Hras	GTPase HRas isoform X1. (192 aa)
	Nras	GTPase NRas. (189 aa)
	Tgfa	Protransforming growth factor alpha. (156 aa)
	Kras	Kirsten rat sarcoma viral oncogene homolog. (163 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Areg	Btc	ENSDORP00000003760	ENSDORP00000015233	Amphiregulin.	Probetacellulin.	0.795
Areg	Csde1	ENSDORP00000003760	ENSDORP00000010910	Amphiregulin.	Cold shock domain-containing protein E1 isoform X1.	0.442
Areg	Egf	ENSDORP00000003760	ENSDORP00000000459	Amphiregulin.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.772
Areg	Egfr	ENSDORP00000003760	ENSDORP00000012273	Amphiregulin.	Receptor protein-tyrosine kinase.	0.980
Areg	Epgn	ENSDORP00000003760	ENSDORP00000013071	Amphiregulin.	Epigen isoform X5.	0.738
Areg	Ereg	ENSDORP00000003760	ENSDORP00000008065	Amphiregulin.	Proepiregulin.	0.883
Areg	Grb2	ENSDORP00000003760	ENSDORP00000027785	Amphiregulin.	Growth factor receptor-bound protein 2.	0.561
Areg	Hbegf	ENSDORP00000003760	ENSDORP00000011785	Amphiregulin.	Proheparin-binding EGF-like growth factor.	0.655
Areg	Hras	ENSDORP00000003760	ENSDORP00000025523	Amphiregulin.	GTPase HRas isoform X1.	0.453
Areg	Kras	ENSDORP00000003760	ENSDORP00000021115	Amphiregulin.	Kirsten rat sarcoma viral oncogene homolog.	0.453
Areg	Kras-2	ENSDORP00000003760	ENSDORP00000010780	Amphiregulin.	GTPase KRas isoform X4.	0.476
Areg	Nras	ENSDORP00000003760	ENSDORP00000022462	Amphiregulin.	GTPase NRas.	0.459
Areg	Shc1	ENSDORP00000003760	ENSDORP00000003514	Amphiregulin.	SHC-transforming protein 1 isoform X2.	0.439
Areg	Tgfa	ENSDORP00000003760	ENSDORP00000021545	Amphiregulin.	Protransforming growth factor alpha.	0.780
Btc	Areg	ENSDORP00000015233	ENSDORP00000003760	Probetacellulin.	Amphiregulin.	0.795
Btc	Csde1	ENSDORP00000015233	ENSDORP00000010910	Probetacellulin.	Cold shock domain-containing protein E1 isoform X1.	0.459
Btc	Egf	ENSDORP00000015233	ENSDORP00000000459	Probetacellulin.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.806
Btc	Egfr	ENSDORP00000015233	ENSDORP00000012273	Probetacellulin.	Receptor protein-tyrosine kinase.	0.973
Btc	Epgn	ENSDORP00000015233	ENSDORP00000013071	Probetacellulin.	Epigen isoform X5.	0.795
Btc	Ereg	ENSDORP00000015233	ENSDORP00000008065	Probetacellulin.	Proepiregulin.	0.793