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Fgf10 Fgf10 Ptbp1 Ptbp1 Grb2 Grb2 Fgf16 Fgf16 Fgf4 Fgf4 Hnrnpa1 Hnrnpa1 Polr2a Polr2a Polr2f Polr2f Hras Hras Esrp1 Esrp1 Polr2h Polr2h Gtf2f2 Gtf2f2 ENSDORP00000024608 ENSDORP00000024608 Fgf8 Fgf8 Spred1 Spred1 Polr2j Polr2j ENSDORP00000023871 ENSDORP00000023871 Fgfr1 Fgfr1 Fgfbp3 Fgfbp3 ENSDORP00000023068 ENSDORP00000023068 Fgfr3-2 Fgfr3-2 Nras Nras LOC105986631 LOC105986631 ENSDORP00000022339 ENSDORP00000022339 Uba52 Uba52 Spry2 Spry2 Fgf18 Fgf18 Ptbp3 Ptbp3 ENSDORP00000021778 ENSDORP00000021778 Fgf9 Fgf9 Kras Kras LOC105993014 LOC105993014 Ppp2ca Ppp2ca LOC106001311 LOC106001311 Kl Kl Cbl Cbl Pik3r1 Pik3r1 Fgfr4 Fgfr4 Polr2d Polr2d ENSDORP00000019733 ENSDORP00000019733 ENSDORP00000019529 ENSDORP00000019529 Mknk2 Mknk2 Flrt1 Flrt1 Fgf2 Fgf2 Fgf6 Fgf6 Ncbp2 Ncbp2 Frs2 Frs2 Fgf1 Fgf1 Fgf7 Fgf7 Polr2k Polr2k ENSDORP00000017361 ENSDORP00000017361 Braf Braf Mapk1 Mapk1 Fgfr2 Fgfr2 Fgfrl1 Fgfrl1 Gab1 Gab1 Polr2g Polr2g Rbfox2 Rbfox2 Ppp2r1a Ppp2r1a Ncbp1 Ncbp1 Fgf5 Fgf5 Fgf17 Fgf17 Spred2 Spred2 Plcg1 Plcg1 Csde1 Csde1 Kras-2 Kras-2 Ptbp2 Ptbp2 Tial1 Tial1 Polr2b Polr2b Fgfr3 Fgfr3 Pik3ca Pik3ca Flrt3 Flrt3 Tia1 Tia1 Ptpn11 Ptpn11 Hnrnpm Hnrnpm Ppp2cb Ppp2cb Mknk1 Mknk1 Fgf20 Fgf20 Rps27a Rps27a Klb Klb Stil Stil Flrt2 Flrt2 Fgf22 Fgf22 Fgfbp1 Fgfbp1 Shc1 Shc1 Mapk3 Mapk3 Galnt3 Galnt3 Gtf2f1 Gtf2f1 Sos1 Sos1 Polr2i Polr2i Polr2e Polr2e Esrp2 Esrp2 Fndc3a Fndc3a Polr2c Polr2c
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
Ptbp1Polypyrimidine tract-binding protein 1 isoform X3. (557 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (52 aa)
Hnrnpa1Heterogeneous nuclear ribonucleoprotein A1 isoform X2. (372 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
Polr2fDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
HrasGTPase HRas isoform X1. (192 aa)
Esrp1Epithelial splicing regulatory protein 1 isoform X1. (681 aa)
Polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
Gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
ENSDORP00000024608annotation not available (540 aa)
Fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
Spred1Sprouty-related, EVH1 domain-containing protein 1. (436 aa)
Polr2jDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
ENSDORP00000023871annotation not available (69 aa)
Fgfr1Fibroblast growth factor receptor. (822 aa)
Fgfbp3Fibroblast growth factor-binding protein 3. (247 aa)
ENSDORP00000023068annotation not available (544 aa)
Fgfr3-2Fibroblast growth factor receptor. (176 aa)
NrasGTPase NRas. (189 aa)
LOC105986631Ubiquitin-like. (77 aa)
ENSDORP00000022339annotation not available (85 aa)
Uba52ubiquitin-60S ribosomal protein L40. (128 aa)
Spry2Protein sprouty homolog 2. (315 aa)
Fgf18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (185 aa)
Ptbp3Polypyrimidine tract-binding protein 3 isoform X1. (554 aa)
ENSDORP00000021778annotation not available (264 aa)
Fgf9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
LOC105993014ubiquitin-40S ribosomal protein S27a pseudogene. (147 aa)
Ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC106001311DNA-directed RNA polymerase II subunit RPB7. (172 aa)
KlKlotho. (1020 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Fgfr4Fibroblast growth factor receptor. (766 aa)
Polr2dDNA-directed RNA polymerase II subunit RPB4. (142 aa)
ENSDORP00000019733annotation not available (100 aa)
ENSDORP00000019529annotation not available (105 aa)
Mknk2MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (464 aa)
Flrt1Leucine-rich repeat transmembrane protein FLRT1. (674 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
Fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (146 aa)
Ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
Frs2Fibroblast growth factor receptor substrate 2. (507 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Polr2kDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
ENSDORP00000017361annotation not available (108 aa)
BrafSerine/threonine-protein kinase B-raf. (705 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Fgfr2Fibroblast growth factor receptor. (819 aa)
Fgfrl1Fibroblast growth factor receptor-like 1. (489 aa)
Gab1GRB2-associated-binding protein 1. (707 aa)
Polr2gDNA-directed RNA polymerase II subunit RPB7. (118 aa)
Rbfox2RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (368 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
Ncbp1LOW QUALITY PROTEIN: nuclear cap-binding protein subunit 1. (779 aa)
Fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (272 aa)
Fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
Spred2Sprouty-related, EVH1 domain-containing protein 2 isoform X2. (421 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Ptbp2Polypyrimidine tract-binding protein 2 isoform X3. (542 aa)
Tial1Nucleolysin TIAR isoform X1. (409 aa)
Polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1047 aa)
Fgfr3Fibroblast growth factor receptor 3. (47 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Flrt3Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
Tia1Nucleolysin TIA-1 isoform p40. (353 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
HnrnpmHeterogeneous nuclear ribonucleoprotein M isoform X3. (730 aa)
Ppp2cbSerine/threonine-protein phosphatase. (309 aa)
Mknk1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (422 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
KlbBeta-klotho. (976 aa)
StilSCL-interrupting locus protein. (1126 aa)
Flrt2Leucine-rich repeat transmembrane protein FLRT2. (660 aa)
Fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
Fgfbp1Fibroblast growth factor-binding protein 1-like. (237 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Galnt3Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
Gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (480 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
Polr2eDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
Esrp2Epithelial splicing regulatory protein 2 isoform X1. (719 aa)
Fndc3aFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
Polr2cDNA-directed RNA polymerase II subunit RPB3. (275 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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