STRINGSTRING
Rnf222 Rnf222 Mapkapk3 Mapkapk3 Akt3 Akt3 Cav1 Cav1 Actl11 Actl11 Mlst8 Mlst8 Cyfip2 Cyfip2 ENSDORP00000027069 ENSDORP00000027069 Bcar1 Bcar1 Akt2 Akt2 Ncf2 Ncf2 Hras Hras Pak2 Pak2 LOC105987731 LOC105987731 Tenm1 Tenm1 Abi1 Abi1 Mapk14 Mapk14 Tenm3 Tenm3 Baiap2 Baiap2 Pxn Pxn Nckap1 Nckap1 Szrd1 Szrd1 LOC105989352 LOC105989352 LOC105987800 LOC105987800 Nos3 Nos3 ENSDORP00000022835 ENSDORP00000022835 Nedd9 Nedd9 Mapkap1 Mapkap1 LOC106002845 LOC106002845 Nras Nras Crk Crk Actb Actb Axl Axl Pgf Pgf Flt1 Flt1 Ncf1 Ncf1 Brk1 Brk1 Kras Kras Vav1 Vav1 ENSDORP00000020585 ENSDORP00000020585 Pik3r1 Pik3r1 Prkacb Prkacb Ptk2 Ptk2 Arvcf Arvcf She She Cyba Cyba Rictor Rictor Vegfc Vegfc Sphk1 Sphk1 Prkcd Prkcd Itgav Itgav Rhoa Rhoa Ctnnd1 Ctnnd1 Jup Jup Lpxn Lpxn ENSDORP00000017275 ENSDORP00000017275 Mapkapk2 Mapkapk2 Pak1 Pak1 Abi2 Abi2 Itgb3 Itgb3 Prkcb Prkcb Shf Shf Stx7 Stx7 Elmo3 Elmo3 Prkaca Prkaca Mapk13 Mapk13 Rac1 Rac1 Nck1 Nck1 Flt4 Flt4 Ncf4 Ncf4 Cyfip1 Cyfip1 Cybb Cybb ENSDORP00000011621 ENSDORP00000011621 Plcg1 Plcg1 Pdpk1 Pdpk1 Vav2 Vav2 Tgfb1i1 Tgfb1i1 Csde1 Csde1 Kras-2 Kras-2 Elmo2 Elmo2 Prkca Prkca Ptk2b Ptk2b Rock1 Rock1 Wasf1 Wasf1 Pik3ca Pik3ca Actl7a Actl7a Actl7b Actl7b Rock2 Rock2 Vegfd Vegfd Cass4 Cass4 Wasf2 Wasf2 Kdr Kdr Shd Shd Pik3cb Pik3cb Tenm4 Tenm4 Akt1 Akt1 Mast3 Mast3 Actrt2 Actrt2 Mtor Mtor Nck2 Nck2 Dock1 Dock1 Wasf3 Wasf3 Nrp1 Nrp1 Vav3 Vav3 Trib3 Trib3 Nckap1l Nckap1l Pak3 Pak3 Mapk12 Mapk12 Vegfb Vegfb Shc2 Shc2 Rasa1 Rasa1 Stx12 Stx12 Fndc3a Fndc3a Tenm2 Tenm2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rnf222RING finger protein 222. (211 aa)
Mapkapk3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (385 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
Actl11Uncharacterized protein LOC105994564; Belongs to the actin family. (1215 aa)
Mlst8Target of rapamycin complex subunit LST8. (326 aa)
Cyfip2Cytoplasmic FMR1-interacting protein 2. (1216 aa)
ENSDORP00000027069annotation not available (71 aa)
Bcar1Breast cancer anti-estrogen resistance protein 1 isoform X1. (931 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Ncf2Neutrophil cytosol factor 2 isoform X1. (526 aa)
HrasGTPase HRas isoform X1. (192 aa)
Pak2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (507 aa)
LOC105987731Uncharacterized protein LOC105987731. (169 aa)
Tenm1Teneurin-1 isoform X1. (2731 aa)
Abi1Abl interactor 1 isoform X1. (461 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Tenm3Teneurin-3. (2673 aa)
Baiap2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (517 aa)
PxnPaxillin isoform X3; Belongs to the paxillin family. (547 aa)
Nckap1Nck-associated protein 1. (1100 aa)
Szrd1SUZ domain-containing protein 1 isoform X1. (152 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
LOC105987800Vascular endothelial growth factor A isoform X2; Belongs to the PDGF/VEGF growth factor family. (185 aa)
Nos3Nitric oxide synthase; Produces nitric oxide (NO). (1201 aa)
ENSDORP00000022835annotation not available (193 aa)
Nedd9Enhancer of filamentation 1 isoform X3. (834 aa)
Mapkap1Target of rapamycin complex 2 subunit MAPKAP1 isoform X1. (522 aa)
LOC106002845Target of rapamycin complex subunit LST8-like. (149 aa)
NrasGTPase NRas. (189 aa)
CrkAdapter molecule crk. (304 aa)
ActbActin, cytoplasmic 1. (375 aa)
AxlTyrosine-protein kinase receptor UFO. (858 aa)
PgfPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (159 aa)
Flt1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1331 aa)
Ncf1Neutrophil cytosol factor 1 isoform X4. (396 aa)
Brk1Protein BRICK1. (75 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
Vav1Proto-oncogene vav. (845 aa)
ENSDORP00000020585annotation not available (80 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
ArvcfArmadillo repeat protein deleted in velo-cardio-facial syndrome. (808 aa)
SheSH2 domain-containing adapter protein E. (504 aa)
CybaCytochrome b-245 light chain. (176 aa)
RictorRapamycin-insensitive companion of mTOR. (1631 aa)
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
Sphk1Sphingosine kinase 1. (372 aa)
PrkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ItgavIntegrin alpha-V; Belongs to the integrin alpha chain family. (1047 aa)
RhoaTransforming protein RhoA. (193 aa)
Ctnnd1Catenin delta-1 isoform X1. (964 aa)
JupJunction plakoglobin isoform X1. (745 aa)
LpxnLeupaxin; Belongs to the paxillin family. (386 aa)
ENSDORP00000017275annotation not available (77 aa)
Mapkapk2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (353 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
Abi2Abl interactor 2 isoform X1. (446 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (766 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
ShfSH2 domain-containing adapter protein F. (239 aa)
Stx7Syntaxin-7 isoform X1; Belongs to the syntaxin family. (261 aa)
Elmo3Engulfment and cell motility protein 3 isoform X1. (719 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Mapk13Mitogen-activated protein kinase. (334 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
Nck1Cytoplasmic protein. (377 aa)
Flt4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa)
Ncf4Neutrophil cytosol factor 4. (341 aa)
Cyfip1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
CybbCytochrome b-245 heavy chain. (570 aa)
ENSDORP00000011621annotation not available (186 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Pdpk13-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
Vav2Guanine nucleotide exchange factor VAV2. (766 aa)
Tgfb1i1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (462 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Elmo2Engulfment and cell motility protein 2 isoform X1. (732 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
Rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
Wasf1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Actl7aActin-like protein 7A; Belongs to the actin family. (439 aa)
Actl7bActin-like protein 7B; Belongs to the actin family. (418 aa)
Rock2Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1114 aa)
VegfdVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (351 aa)
Cass4Cas scaffolding protein family member 4. (743 aa)
Wasf2wiskott-Aldrich syndrome protein family member 2. (496 aa)
KdrVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1352 aa)
ShdSH2 domain-containing adapter protein D. (313 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Tenm4Teneurin-4 isoform X1. (2638 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Actrt2Actin-related protein T2; Belongs to the actin family. (377 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
Nck2Cytoplasmic protein. (380 aa)
Dock1Dedicator of cytokinesis protein 1 isoform X2; Belongs to the DOCK family. (1870 aa)
Wasf3wiskott-Aldrich syndrome protein family member 3. (503 aa)
Nrp1Neuropilin; Belongs to the neuropilin family. (735 aa)
Vav3Guanine nucleotide exchange factor VAV3. (847 aa)
Trib3Tribbles homolog 3. (357 aa)
Nckap1lNck-associated protein 1-like. (1029 aa)
Pak3Non-specific serine/threonine protein kinase. (559 aa)
Mapk12Mitogen-activated protein kinase. (351 aa)
VegfbVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (204 aa)
Shc2SHC-transforming protein 2. (513 aa)
Rasa1Ras GTPase-activating protein 1. (813 aa)
Stx12Syntaxin-12; Belongs to the syntaxin family. (269 aa)
Fndc3aFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
Tenm2Teneurin-2 isoform X3. (2765 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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