23 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ptprz1	Receptor-type tyrosine-protein phosphatase zeta. (2286 aa)
	Mycn	N-myc proto-oncogene protein. (461 aa)
	Pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	Ros1	Tyrosine-protein kinase receptor. (2332 aa)
	Pik3cb	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
	Ptn	Pleiotrophin. (136 aa)
	Mast3	Microtubule associated serine/threonine kinase 3. (71 aa)
	Shc1	SHC-transforming protein 1 isoform X2. (473 aa)
	Mdk	Midkine. (159 aa)
	ENSDORP00000025871	annotation not available (284 aa)
	Stat3	Signal transducer and activator of transcription. (770 aa)
	ENSDORP00000022774	annotation not available (389 aa)
	Pik3r1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	Prdm1	PR domain zinc finger protein 1 isoform X1. (860 aa)
	Alk	Tyrosine-protein kinase receptor. (1244 aa)
	Hdac2	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
	Jak3	Tyrosine-protein kinase JAK3. (999 aa)
	Hdac3	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (432 aa)
	Plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
	Hdac1	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (477 aa)
	Ltk	Tyrosine-protein kinase receptor. (556 aa)
	Ep300	Histone acetyltransferase p300. (2345 aa)
	Ptpn6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Alk	Jak3	ENSDORP00000012877	ENSDORP00000012002	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase JAK3.	0.890
Alk	Mast3	ENSDORP00000012877	ENSDORP00000003965	Tyrosine-protein kinase receptor.	Microtubule associated serine/threonine kinase 3.	0.889
Alk	Mdk	ENSDORP00000012877	ENSDORP00000026716	Tyrosine-protein kinase receptor.	Midkine.	0.874
Alk	Mycn	ENSDORP00000012877	ENSDORP00000009310	Tyrosine-protein kinase receptor.	N-myc proto-oncogene protein.	0.669
Alk	Pik3ca	ENSDORP00000012877	ENSDORP00000008976	Tyrosine-protein kinase receptor.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.922
Alk	Pik3cb	ENSDORP00000012877	ENSDORP00000005935	Tyrosine-protein kinase receptor.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.883
Alk	Pik3r1	ENSDORP00000012877	ENSDORP00000020150	Tyrosine-protein kinase receptor.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.917
Alk	Plcg1	ENSDORP00000012877	ENSDORP00000011410	Tyrosine-protein kinase receptor.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.920
Alk	Ptn	ENSDORP00000012877	ENSDORP00000005713	Tyrosine-protein kinase receptor.	Pleiotrophin.	0.900
Alk	Ptpn6	ENSDORP00000012877	ENSDORP00000001109	Tyrosine-protein kinase receptor.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.736
Alk	Ptprz1	ENSDORP00000012877	ENSDORP00000009517	Tyrosine-protein kinase receptor.	Receptor-type tyrosine-protein phosphatase zeta.	0.693
Alk	Shc1	ENSDORP00000012877	ENSDORP00000003514	Tyrosine-protein kinase receptor.	SHC-transforming protein 1 isoform X2.	0.820
Alk	Stat3	ENSDORP00000012877	ENSDORP00000024461	Tyrosine-protein kinase receptor.	Signal transducer and activator of transcription.	0.790
ENSDORP00000022774	ENSDORP00000025871	ENSDORP00000022774	ENSDORP00000025871	annotation not available	annotation not available	0.649
ENSDORP00000022774	Ep300	ENSDORP00000022774	ENSDORP00000009643	annotation not available	Histone acetyltransferase p300.	0.918
ENSDORP00000022774	Hdac2	ENSDORP00000022774	ENSDORP00000012520	annotation not available	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.988
ENSDORP00000022774	Hdac3	ENSDORP00000022774	ENSDORP00000011840	annotation not available	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.639
ENSDORP00000022774	Mycn	ENSDORP00000022774	ENSDORP00000009310	annotation not available	N-myc proto-oncogene protein.	0.547
ENSDORP00000022774	Prdm1	ENSDORP00000022774	ENSDORP00000013387	annotation not available	PR domain zinc finger protein 1 isoform X1.	0.654
ENSDORP00000022774	Stat3	ENSDORP00000022774	ENSDORP00000024461	annotation not available	Signal transducer and activator of transcription.	0.860