STRINGSTRING
Plcg1 Plcg1 Inpp5d Inpp5d Src Src Itgb3 Itgb3 Itgav Itgav Pecam1 Pecam1 Ptpn11 Ptpn11 Yes1 Yes1 Ptpn6 Ptpn6 Lyn Lyn Fndc3a Fndc3a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Inpp5dPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1186 aa)
SrcTyrosine-protein kinase. (539 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (766 aa)
ItgavIntegrin alpha-V; Belongs to the integrin alpha chain family. (1047 aa)
Pecam1Platelet endothelial cell adhesion molecule. (715 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Yes1Tyrosine-protein kinase. (541 aa)
Ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
LynTyrosine-protein kinase. (512 aa)
Fndc3aFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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