STRINGSTRING
Kras-2 Kras-2 Grb2 Grb2 Grb7 Grb7 Sos1 Sos1 Shc1 Shc1 Angptl7 Angptl7 Mast3 Mast3 Angpt2 Angpt2 Pik3cb Pik3cb Tie1-2 Tie1-2 Ptpn11 Ptpn11 Angpt4 Angpt4 Pik3ca Pik3ca Hras Hras Tek Tek Nras Nras Dok2 Dok2 Kras Kras Pik3r1 Pik3r1 Tie1 Tie1 Grb14 Grb14 Angpt1 Angpt1 Csde1 Csde1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Kras-2GTPase KRas isoform X4. (189 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Grb7Growth factor receptor-bound protein 7. (531 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Angptl7Angiopoietin-related protein 7. (344 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Angpt2Angiopoietin-2. (495 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Tie1-2Tyrosine kinase with immunoglobulin like and EGF like domains 1. (446 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Angpt4Angiopoietin-4. (499 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
HrasGTPase HRas isoform X1. (192 aa)
TekAngiopoietin-1 receptor isoform X1. (1125 aa)
NrasGTPase NRas. (189 aa)
Dok2Docking protein 2. (404 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Tie1Tyrosine-protein kinase receptor Tie-1 isoform X2. (651 aa)
Grb14Growth factor receptor-bound protein 14. (507 aa)
Angpt1Angiopoietin-1 isoform X1. (498 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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