29 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Vav3	Guanine nucleotide exchange factor VAV3. (847 aa)
	Clec5a	C-type lectin domain family 5 member A. (167 aa)
	Syk	Tyrosine-protein kinase. (633 aa)
	Kras-2	GTPase KRas isoform X4. (189 aa)
	Pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	Sirpa	Tyrosine-protein phosphatase non-receptor type substrate 1. (216 aa)
	Kras	Kirsten rat sarcoma viral oncogene homolog. (163 aa)
	Pik3r1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	Lcp2	Lymphocyte cytosolic protein 2. (314 aa)
	Plcg2	Phosphoinositide phospholipase C. (1065 aa)
	Nras	GTPase NRas. (189 aa)
	Lat	Linker for activation of T-cells family member 1 isoform X1. (234 aa)
	Grap2	GRB2-related adapter protein 2 isoform X2. (324 aa)
	Rac1	Ras-related C3 botulinum toxin substrate 1. (187 aa)
	Siglec15	Sialic acid binding Ig like lectin 15. (223 aa)
	Plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
	Vav2	Guanine nucleotide exchange factor VAV2. (766 aa)
	Csde1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	Pik3cb	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
	Trem2	Triggering receptor expressed on myeloid cells 2. (251 aa)
	Mast3	Microtubule associated serine/threonine kinase 3. (71 aa)
	Shc1	SHC-transforming protein 1 isoform X2. (473 aa)
	Tyrobp	TYRO protein tyrosine kinase-binding protein. (114 aa)
	Grb2	Growth factor receptor-bound protein 2. (217 aa)
	Klrk1	NKG2-D type II integral membrane protein isoform X2. (123 aa)
	Sos1	Son of sevenless homolog 1. (1301 aa)
	Hras	GTPase HRas isoform X1. (192 aa)
	Btk	Tyrosine-protein kinase. (659 aa)
	Spns1	Protein spinster homolog 1. (528 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Btk	Csde1	ENSDORP00000025516	ENSDORP00000010910	Tyrosine-protein kinase.	Cold shock domain-containing protein E1 isoform X1.	0.450
Btk	Grap2	ENSDORP00000025516	ENSDORP00000014506	Tyrosine-protein kinase.	GRB2-related adapter protein 2 isoform X2.	0.842
Btk	Grb2	ENSDORP00000025516	ENSDORP00000027785	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.868
Btk	Hras	ENSDORP00000025516	ENSDORP00000025523	Tyrosine-protein kinase.	GTPase HRas isoform X1.	0.478
Btk	Klrk1	ENSDORP00000025516	ENSDORP00000027252	Tyrosine-protein kinase.	NKG2-D type II integral membrane protein isoform X2.	0.466
Btk	Kras	ENSDORP00000025516	ENSDORP00000021115	Tyrosine-protein kinase.	Kirsten rat sarcoma viral oncogene homolog.	0.478
Btk	Kras-2	ENSDORP00000025516	ENSDORP00000010780	Tyrosine-protein kinase.	GTPase KRas isoform X4.	0.509
Btk	Lat	ENSDORP00000025516	ENSDORP00000015026	Tyrosine-protein kinase.	Linker for activation of T-cells family member 1 isoform X1.	0.676
Btk	Lcp2	ENSDORP00000025516	ENSDORP00000015471	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.825
Btk	Mast3	ENSDORP00000025516	ENSDORP00000003965	Tyrosine-protein kinase.	Microtubule associated serine/threonine kinase 3.	0.888
Btk	Nras	ENSDORP00000025516	ENSDORP00000022462	Tyrosine-protein kinase.	GTPase NRas.	0.490
Btk	Pik3ca	ENSDORP00000025516	ENSDORP00000008976	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.890
Btk	Pik3cb	ENSDORP00000025516	ENSDORP00000005935	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.888
Btk	Pik3r1	ENSDORP00000025516	ENSDORP00000020150	Tyrosine-protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.898
Btk	Plcg1	ENSDORP00000025516	ENSDORP00000011410	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.918
Btk	Plcg2	ENSDORP00000025516	ENSDORP00000015075	Tyrosine-protein kinase.	Phosphoinositide phospholipase C.	0.961
Btk	Rac1	ENSDORP00000025516	ENSDORP00000013529	Tyrosine-protein kinase.	Ras-related C3 botulinum toxin substrate 1.	0.610
Btk	Shc1	ENSDORP00000025516	ENSDORP00000003514	Tyrosine-protein kinase.	SHC-transforming protein 1 isoform X2.	0.622
Btk	Sirpa	ENSDORP00000025516	ENSDORP00000006503	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type substrate 1.	0.482
Btk	Sos1	ENSDORP00000025516	ENSDORP00000002200	Tyrosine-protein kinase.	Son of sevenless homolog 1.	0.674