18 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105986631	Ubiquitin-like. (77 aa)
	Uba52	ubiquitin-60S ribosomal protein L40. (128 aa)
	LOC105993014	ubiquitin-40S ribosomal protein S27a pseudogene. (147 aa)
	ENSDORP00000019733	annotation not available (100 aa)
	Tgfbr1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (490 aa)
	Smad2	Mothers against decapentaplegic homolog. (467 aa)
	Ppp1r15a	Protein phosphatase 1 regulatory subunit 15A. (77 aa)
	Tgfbr2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
	Bambi	BMP and activin membrane-bound inhibitor homolog. (251 aa)
	Stub1	E3 ubiquitin-protein ligase CHIP. (267 aa)
	Rps27a	ubiquitin-40S ribosomal protein S27a. (156 aa)
	Tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (130 aa)
	Mtmr4	Myotubularin-related protein 4 isoform X1. (204 aa)
	Ldlrad4	Low-density lipoprotein receptor class A domain-containing protein 4. (306 aa)
	Smad7	Mothers against decapentaplegic homolog. (427 aa)
	Strap	Serine-threonine kinase receptor-associated protein. (293 aa)
	Smad3	Mothers against decapentaplegic homolog. (425 aa)
	Smurf2	E3 ubiquitin-protein ligase SMURF2. (722 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bambi	Smad2	ENSDORP00000010689	ENSDORP00000018085	BMP and activin membrane-bound inhibitor homolog.	Mothers against decapentaplegic homolog.	0.625
Bambi	Smad3	ENSDORP00000010689	ENSDORP00000023202	BMP and activin membrane-bound inhibitor homolog.	Mothers against decapentaplegic homolog.	0.620
Bambi	Smad7	ENSDORP00000010689	ENSDORP00000027241	BMP and activin membrane-bound inhibitor homolog.	Mothers against decapentaplegic homolog.	0.859
Bambi	Tgfb1	ENSDORP00000010689	ENSDORP00000003371	BMP and activin membrane-bound inhibitor homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.748
Bambi	Tgfbr1	ENSDORP00000010689	ENSDORP00000018470	BMP and activin membrane-bound inhibitor homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.928
Bambi	Tgfbr2	ENSDORP00000010689	ENSDORP00000014157	BMP and activin membrane-bound inhibitor homolog.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.693
ENSDORP00000019733	LOC105986631	ENSDORP00000019733	ENSDORP00000022383	annotation not available	Ubiquitin-like.	0.986
ENSDORP00000019733	Smad2	ENSDORP00000019733	ENSDORP00000018085	annotation not available	Mothers against decapentaplegic homolog.	0.565
ENSDORP00000019733	Smad3	ENSDORP00000019733	ENSDORP00000023202	annotation not available	Mothers against decapentaplegic homolog.	0.543
ENSDORP00000019733	Smad7	ENSDORP00000019733	ENSDORP00000027241	annotation not available	Mothers against decapentaplegic homolog.	0.607
ENSDORP00000019733	Smurf2	ENSDORP00000019733	ENSDORP00000024284	annotation not available	E3 ubiquitin-protein ligase SMURF2.	0.952
ENSDORP00000019733	Stub1	ENSDORP00000019733	ENSDORP00000006060	annotation not available	E3 ubiquitin-protein ligase CHIP.	0.723
ENSDORP00000019733	Tgfbr1	ENSDORP00000019733	ENSDORP00000018470	annotation not available	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.633
ENSDORP00000019733	Tgfbr2	ENSDORP00000019733	ENSDORP00000014157	annotation not available	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.663
ENSDORP00000019733	Uba52	ENSDORP00000019733	ENSDORP00000022137	annotation not available	ubiquitin-60S ribosomal protein L40.	0.994
LOC105986631	ENSDORP00000019733	ENSDORP00000022383	ENSDORP00000019733	Ubiquitin-like.	annotation not available	0.986
LOC105986631	LOC105993014	ENSDORP00000022383	ENSDORP00000020911	Ubiquitin-like.	ubiquitin-40S ribosomal protein S27a pseudogene.	0.986
LOC105986631	Ldlrad4	ENSDORP00000022383	ENSDORP00000024983	Ubiquitin-like.	Low-density lipoprotein receptor class A domain-containing protein 4.	0.426
LOC105986631	Rps27a	ENSDORP00000022383	ENSDORP00000005888	Ubiquitin-like.	ubiquitin-40S ribosomal protein S27a.	0.986
LOC105986631	Smad2	ENSDORP00000022383	ENSDORP00000018085	Ubiquitin-like.	Mothers against decapentaplegic homolog.	0.423