26 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Klrk1	NKG2-D type II integral membrane protein isoform X2. (123 aa)
	Hras	GTPase HRas isoform X1. (192 aa)
	Btk	Tyrosine-protein kinase. (659 aa)
	Spns1	Protein spinster homolog 1. (528 aa)
	Trem2	Triggering receptor expressed on myeloid cells 2. (251 aa)
	Nras	GTPase NRas. (189 aa)
	Syk	Tyrosine-protein kinase. (633 aa)
	Kras	Kirsten rat sarcoma viral oncogene homolog. (163 aa)
	Pik3r1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	Lcp2	Lymphocyte cytosolic protein 2. (314 aa)
	Plcg2	Phosphoinositide phospholipase C. (1065 aa)
	Lat	Linker for activation of T-cells family member 1 isoform X1. (234 aa)
	Grap2	GRB2-related adapter protein 2 isoform X2. (324 aa)
	Rac1	Ras-related C3 botulinum toxin substrate 1. (187 aa)
	Plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
	Vav2	Guanine nucleotide exchange factor VAV2. (766 aa)
	Csde1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	Kras-2	GTPase KRas isoform X4. (189 aa)
	Pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	Pik3cb	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
	Mast3	Microtubule associated serine/threonine kinase 3. (71 aa)
	Shc1	SHC-transforming protein 1 isoform X2. (473 aa)
	Tyrobp	TYRO protein tyrosine kinase-binding protein. (114 aa)
	Sos1	Son of sevenless homolog 1. (1301 aa)
	Vav3	Guanine nucleotide exchange factor VAV3. (847 aa)
	Grb2	Growth factor receptor-bound protein 2. (217 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Btk	Csde1	ENSDORP00000025516	ENSDORP00000010910	Tyrosine-protein kinase.	Cold shock domain-containing protein E1 isoform X1.	0.450
Btk	Grap2	ENSDORP00000025516	ENSDORP00000014506	Tyrosine-protein kinase.	GRB2-related adapter protein 2 isoform X2.	0.842
Btk	Grb2	ENSDORP00000025516	ENSDORP00000027785	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.868
Btk	Hras	ENSDORP00000025516	ENSDORP00000025523	Tyrosine-protein kinase.	GTPase HRas isoform X1.	0.478
Btk	Klrk1	ENSDORP00000025516	ENSDORP00000027252	Tyrosine-protein kinase.	NKG2-D type II integral membrane protein isoform X2.	0.466
Btk	Kras	ENSDORP00000025516	ENSDORP00000021115	Tyrosine-protein kinase.	Kirsten rat sarcoma viral oncogene homolog.	0.478
Btk	Kras-2	ENSDORP00000025516	ENSDORP00000010780	Tyrosine-protein kinase.	GTPase KRas isoform X4.	0.509
Btk	Lat	ENSDORP00000025516	ENSDORP00000015026	Tyrosine-protein kinase.	Linker for activation of T-cells family member 1 isoform X1.	0.676
Btk	Lcp2	ENSDORP00000025516	ENSDORP00000015471	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.825
Btk	Mast3	ENSDORP00000025516	ENSDORP00000003965	Tyrosine-protein kinase.	Microtubule associated serine/threonine kinase 3.	0.888
Btk	Nras	ENSDORP00000025516	ENSDORP00000022462	Tyrosine-protein kinase.	GTPase NRas.	0.490
Btk	Pik3ca	ENSDORP00000025516	ENSDORP00000008976	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.890
Btk	Pik3cb	ENSDORP00000025516	ENSDORP00000005935	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.888
Btk	Pik3r1	ENSDORP00000025516	ENSDORP00000020150	Tyrosine-protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.898
Btk	Plcg1	ENSDORP00000025516	ENSDORP00000011410	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.918
Btk	Plcg2	ENSDORP00000025516	ENSDORP00000015075	Tyrosine-protein kinase.	Phosphoinositide phospholipase C.	0.961
Btk	Rac1	ENSDORP00000025516	ENSDORP00000013529	Tyrosine-protein kinase.	Ras-related C3 botulinum toxin substrate 1.	0.610
Btk	Shc1	ENSDORP00000025516	ENSDORP00000003514	Tyrosine-protein kinase.	SHC-transforming protein 1 isoform X2.	0.622
Btk	Sos1	ENSDORP00000025516	ENSDORP00000002200	Tyrosine-protein kinase.	Son of sevenless homolog 1.	0.674
Btk	Syk	ENSDORP00000025516	ENSDORP00000000466	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.956