STRINGSTRING
Epha5 Epha5 Efna1 Efna1 Actl11 Actl11 Arpc3 Arpc3 Fmn2 Fmn2 Efnb1 Efnb1 Arhgef7 Arhgef7 Efna2 Efna2 LOC105997620 LOC105997620 Pak2 Pak2 LOC105994487 LOC105994487 Efnb3 Efnb3 Ephb1 Ephb1 Arpc4 Arpc4 Dstn Dstn LOC105989352 LOC105989352 ENSDORP00000022835 ENSDORP00000022835 Grin1 Grin1 Efna4 Efna4 Actb Actb Epha10 Epha10 ENSDORP00000021938 ENSDORP00000021938 Arpc5l Arpc5l ENSDORP00000021076 ENSDORP00000021076 ENSDORP00000020814 ENSDORP00000020814 Arpc5 Arpc5 Ptk2 Ptk2 Sdc2 Sdc2 Rhoa Rhoa ENSDORP00000017594 ENSDORP00000017594 Itsn1 Itsn1 Efna5 Efna5 Pak1 Pak1 Tiam1 Tiam1 Epha2 Epha2 LOC105989882 LOC105989882 Psenen Psenen ENSDORP00000016358 ENSDORP00000016358 Fmn1 Fmn1 Src Src Arpc2 Arpc2 Arpc1a Arpc1a Limk2 Limk2 Kalrn Kalrn Epha8 Epha8 Rac1 Rac1 Epha7 Epha7 Mmp2 Mmp2 Sdcbp2 Sdcbp2 ENSDORP00000011621 ENSDORP00000011621 Aph1b Aph1b Ephb2 Ephb2 Actr3 Actr3 Vav2 Vav2 Wasl Wasl Aph1a Aph1a Efnb2 Efnb2 Arhgef28 Arhgef28 Rock1 Rock1 Cfl1 Cfl1 Epha6 Epha6 Ephb6 Ephb6 Actl7a Actl7a Actl7b Actl7b ENSDORP00000007707 ENSDORP00000007707 Rock2 Rock2 Ephb4 Ephb4 Efna3 Efna3 Sdcbp Sdcbp Cfl2 Cfl2 Epha4 Epha4 Git1 Git1 Epha3 Epha3 Actrt2 Actrt2 Nck2 Nck2 Ncstn Ncstn Ephb3 Ephb3 Yes1 Yes1 Vav3 Vav3 Epha1 Epha1 Pak3 Pak3 Actr3b Actr3b Psen1 Psen1 Psen2 Psen2 Grin2b Grin2b Actr2 Actr2 Rasa1 Rasa1 Lyn Lyn Arpc1b Arpc1b Fndc3a Fndc3a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Epha5Ephrin type-A receptor 5 isoform X1. (1038 aa)
Efna1ephrin-A1; Belongs to the ephrin family. (203 aa)
Actl11Uncharacterized protein LOC105994564; Belongs to the actin family. (1215 aa)
Arpc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (154 aa)
Fmn2Formin-2. (1560 aa)
Efnb1ephrin-B1; Belongs to the ephrin family. (345 aa)
Arhgef7Rho guanine nucleotide exchange factor 7. (820 aa)
Efna2ephrin-A2; Belongs to the ephrin family. (197 aa)
LOC105997620Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (282 aa)
Pak2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (507 aa)
LOC105994487Ephrin type-B receptor 1-like. (304 aa)
Efnb3ephrin-B3; Belongs to the ephrin family. (340 aa)
Ephb1Ephrin type-B receptor 1. (836 aa)
Arpc4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
DstnDestrin; Belongs to the actin-binding proteins ADF family. (165 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
ENSDORP00000022835annotation not available (193 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
Efna4ephrin-A4; Belongs to the ephrin family. (204 aa)
ActbActin, cytoplasmic 1. (375 aa)
Epha10Ephrin type-A receptor 10. (944 aa)
ENSDORP00000021938annotation not available (332 aa)
Arpc5lActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
ENSDORP00000021076annotation not available (173 aa)
ENSDORP00000020814annotation not available (97 aa)
Arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
Sdc2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
RhoaTransforming protein RhoA. (193 aa)
ENSDORP00000017594annotation not available (251 aa)
Itsn1Intersectin-1. (1221 aa)
Efna5ephrin-A5 isoform X1; Belongs to the ephrin family. (188 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
Tiam1T-lymphoma invasion and metastasis-inducing protein 1. (1588 aa)
Epha2Ephrin type-A receptor 2 isoform X2. (976 aa)
LOC105989882Actin-related protein 2/3 complex subunit 2 pseudogene. (295 aa)
PsenenGamma-secretase subunit PEN-2. (101 aa)
ENSDORP00000016358annotation not available (337 aa)
Fmn1Formin-1. (1397 aa)
SrcTyrosine-protein kinase. (539 aa)
Arpc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (209 aa)
Arpc1aActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (382 aa)
Limk2LIM domain kinase 2 isoform X2. (617 aa)
KalrnKalirin isoform X2. (2981 aa)
Epha8Ephrin type-A receptor 8. (981 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
Epha7Ephrin type-A receptor 7 isoform X1. (998 aa)
Mmp272 kDa type IV collagenase. (126 aa)
Sdcbp2Syntenin-2. (294 aa)
ENSDORP00000011621annotation not available (186 aa)
Aph1bGamma-secretase subunit APH-1B. (257 aa)
Ephb2Ephrin type-B receptor 2 isoform X2. (1018 aa)
Actr3Actin-related protein 3; Belongs to the actin family. (403 aa)
Vav2Guanine nucleotide exchange factor VAV2. (766 aa)
WaslNeural Wiskott-Aldrich syndrome protein. (506 aa)
Aph1aGamma-secretase subunit APH-1A. (265 aa)
Efnb2ephrin-B2; Belongs to the ephrin family. (325 aa)
Arhgef28Rho guanine nucleotide exchange factor 28 isoform X2. (1676 aa)
Rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
Cfl1Cofilin-1; Belongs to the actin-binding proteins ADF family. (168 aa)
Epha6Receptor protein-tyrosine kinase. (288 aa)
Ephb6Ephrin type-B receptor 6. (1015 aa)
Actl7aActin-like protein 7A; Belongs to the actin family. (439 aa)
Actl7bActin-like protein 7B; Belongs to the actin family. (418 aa)
ENSDORP00000007707annotation not available (165 aa)
Rock2Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1114 aa)
Ephb4Ephrin type-B receptor 4. (934 aa)
Efna3ephrin-A3 isoform X1; Belongs to the ephrin family. (230 aa)
SdcbpSyntenin-1. (244 aa)
Cfl2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
Epha4Ephrin type-A receptor 4 isoform X1. (986 aa)
Git1ARF GTPase-activating protein GIT1. (758 aa)
Epha3Ephrin type-A receptor 3 isoform X1. (984 aa)
Actrt2Actin-related protein T2; Belongs to the actin family. (377 aa)
Nck2Cytoplasmic protein. (380 aa)
NcstnNicastrin. (698 aa)
Ephb3Ephrin type-B receptor 3. (998 aa)
Yes1Tyrosine-protein kinase. (541 aa)
Vav3Guanine nucleotide exchange factor VAV3. (847 aa)
Epha1Ephrin type-A receptor 1 isoform X1. (973 aa)
Pak3Non-specific serine/threonine protein kinase. (559 aa)
Actr3bActin-related protein 3B; Belongs to the actin family. (407 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
Grin2bGlutamate receptor ionotropic, NMDA 2B. (1103 aa)
Actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
Rasa1Ras GTPase-activating protein 1. (813 aa)
LynTyrosine-protein kinase. (512 aa)
Arpc1bActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
Fndc3aFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.