41 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Mast3	Microtubule associated serine/threonine kinase 3. (71 aa)
	Rapgef1	Rap guanine nucleotide exchange factor 1 isoform X1. (1198 aa)
	ENSDORP00000002235	annotation not available (390 aa)
	Il2ra	Interleukin-2 receptor subunit alpha. (269 aa)
	Rps27a	ubiquitin-40S ribosomal protein S27a. (156 aa)
	Pik3cb	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
	Ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
	Pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	Gab2	GRB2-associated-binding protein 2. (608 aa)
	Ywhaz	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
	Sos1	Son of sevenless homolog 1. (1301 aa)
	Csf2	Granulocyte-macrophage colony-stimulating factor. (140 aa)
	Ptpn6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	Lyn	Tyrosine-protein kinase. (512 aa)
	Syk	Tyrosine-protein kinase. (633 aa)
	Stat5a	Signal transducer and activator of transcription. (793 aa)
	Inppl1	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1240 aa)
	Pik3cd	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
	ENSDORP00000019733	annotation not available (100 aa)
	Pik3r1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	Cbl	E3 ubiquitin-protein ligase CBL. (51 aa)
	Vav1	Proto-oncogene vav. (845 aa)
	LOC105993014	ubiquitin-40S ribosomal protein S27a pseudogene. (147 aa)
	Crkl	Crk-like protein. (303 aa)
	LOC106000559	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
	Uba52	ubiquitin-60S ribosomal protein L40. (128 aa)
	Crk	Adapter molecule crk. (304 aa)
	LOC105986631	Ubiquitin-like. (77 aa)
	Grb2	Growth factor receptor-bound protein 2. (217 aa)
	Jak3	Tyrosine-protein kinase JAK3. (999 aa)
	Jak1	Tyrosine-protein kinase. (1155 aa)
	Il5ra	Interleukin-5 receptor subunit alpha. (392 aa)
	Prkaca	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
	Il2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
	Inpp5d	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1186 aa)
	Il5	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
	Tec	Tyrosine-protein kinase. (631 aa)
	Pik3r3	Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
	Il2rg	Cytokine receptor common subunit gamma. (94 aa)
	Jak2	Tyrosine-protein kinase. (1037 aa)
	Shc1	SHC-transforming protein 1 isoform X2. (473 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cbl	Crk	ENSDORP00000020259	ENSDORP00000022183	E3 ubiquitin-protein ligase CBL.	Adapter molecule crk.	0.994
Cbl	Crkl	ENSDORP00000020259	ENSDORP00000021103	E3 ubiquitin-protein ligase CBL.	Crk-like protein.	0.996
Cbl	ENSDORP00000002235	ENSDORP00000020259	ENSDORP00000002235	E3 ubiquitin-protein ligase CBL.	annotation not available	0.482
Cbl	ENSDORP00000019733	ENSDORP00000020259	ENSDORP00000019733	E3 ubiquitin-protein ligase CBL.	annotation not available	0.883
Cbl	Grb2	ENSDORP00000020259	ENSDORP00000027785	E3 ubiquitin-protein ligase CBL.	Growth factor receptor-bound protein 2.	0.994
Cbl	Inpp5d	ENSDORP00000020259	ENSDORP00000014465	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1.	0.689
Cbl	Inppl1	ENSDORP00000020259	ENSDORP00000010606	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2.	0.889
Cbl	Jak1	ENSDORP00000020259	ENSDORP00000012658	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.732
Cbl	Jak2	ENSDORP00000020259	ENSDORP00000019264	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.740
Cbl	Jak3	ENSDORP00000020259	ENSDORP00000012002	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase JAK3.	0.655
Cbl	LOC105986631	ENSDORP00000020259	ENSDORP00000022383	E3 ubiquitin-protein ligase CBL.	Ubiquitin-like.	0.860
Cbl	LOC105993014	ENSDORP00000020259	ENSDORP00000020911	E3 ubiquitin-protein ligase CBL.	ubiquitin-40S ribosomal protein S27a pseudogene.	0.883
Cbl	LOC106000559	ENSDORP00000020259	ENSDORP00000021660	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.825
Cbl	Lyn	ENSDORP00000020259	ENSDORP00000000698	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.975
Cbl	Mast3	ENSDORP00000020259	ENSDORP00000003965	E3 ubiquitin-protein ligase CBL.	Microtubule associated serine/threonine kinase 3.	0.975
Cbl	Pik3ca	ENSDORP00000020259	ENSDORP00000008976	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.924
Cbl	Pik3cb	ENSDORP00000020259	ENSDORP00000005935	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.924
Cbl	Pik3cd	ENSDORP00000020259	ENSDORP00000011666	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.825
Cbl	Pik3r1	ENSDORP00000020259	ENSDORP00000020150	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.995
Cbl	Pik3r3	ENSDORP00000020259	ENSDORP00000016327	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit gamma.	0.955