Your Input: | |
| | Rpa2 | Replication protein A 32 kDa subunit isoform X1. (255 aa) |
| | ENSDORP00000027720 | annotation not available (121 aa) |
| | Chek1 | Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa) |
| | Akt3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | Ppp2r5c | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa) |
| | ENSDORP00000027400 | annotation not available (304 aa) |
| | ENSDORP00000027329 | annotation not available (278 aa) |
| | Ppp1r13b | Apoptosis-stimulating of p53 protein 1 isoform X3. (1087 aa) |
| | Mlst8 | Target of rapamycin complex subunit LST8. (326 aa) |
| | Map2k6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | Prkab2 | 5'-AMP-activated protein kinase subunit beta-2. (268 aa) |
| | Tbpl1 | TATA box-binding protein-like protein 1 isoform X2. (186 aa) |
| | Akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | Hipk1 | Homeodomain-interacting protein kinase 1. (1139 aa) |
| | Brpf3-2 | Bromodomain and PHD finger-containing protein 3. (626 aa) |
| | ENSDORP00000025857 | annotation not available (163 aa) |
| | Zfp385a | Zinc finger protein 385A isoform X2. (383 aa) |
| | Taf7 | Transcription initiation factor TFIID subunit 7. (348 aa) |
| | Dyrk2 | Dual specificity tyrosine-phosphorylation-regulated kinase 2. (599 aa) |
| | Meaf6 | Chromatin modification-related protein MEAF6 isoform X2. (206 aa) |
| | Pip4p2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (198 aa) |
| | Rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | Taf13 | Transcription initiation factor TFIID subunit 13. (124 aa) |
| | Ttc5 | Tetratricopeptide repeat protein 5 isoform X1. (388 aa) |
| | Rhno1 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1. (235 aa) |
| | ENSDORP00000024608 | annotation not available (540 aa) |
| | Mapk14 | Mitogen-activated protein kinase. (360 aa) |
| | Usp2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (396 aa) |
| | Trp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa) |
| | Prkag1 | 5'-AMP-activated protein kinase subunit gamma-1. (330 aa) |
| | Ing1 | Inhibitor of growth protein. (77 aa) |
| | Tp53inp1 | Tumor protein p53-inducible nuclear protein 1 isoform X1. (240 aa) |
| | ENSDORP00000023068 | annotation not available (544 aa) |
| | ENSDORP00000022774 | annotation not available (389 aa) |
| | Ubb | polyubiquitin-B. (155 aa) |
| | Mapkap1 | Target of rapamycin complex 2 subunit MAPKAP1 isoform X1. (522 aa) |
| | ENSDORP00000022541 | annotation not available (113 aa) |
| | LOC106002845 | Target of rapamycin complex subunit LST8-like. (149 aa) |
| | LOC105986631 | Ubiquitin-like. (77 aa) |
| | Uba52 | ubiquitin-60S ribosomal protein L40. (128 aa) |
| | Tdrd3 | Tudor domain-containing protein 3 isoform X2. (744 aa) |
| | Prkab1 | 5'-AMP-activated protein kinase subunit beta-1. (270 aa) |
| | Rfc4 | Replication factor C subunit 4 isoform X1. (97 aa) |
| | LOC105998920 | DNA repair protein RAD50-like. (122 aa) |
| | Rmi2 | recQ-mediated genome instability protein 2. (148 aa) |
| | Tbp | TATA-box-binding protein. (318 aa) |
| | Chd4 | chromodomain-helicase-DNA-binding protein 4 isoform X2. (1942 aa) |
| | LOC105993014 | ubiquitin-40S ribosomal protein S27a pseudogene. (147 aa) |
| | Kxd1 | kxDL motif-containing protein 1 isoform X2. (183 aa) |
| | Ppp2ca | Serine/threonine-protein phosphatase. (309 aa) |
| | Cdk5r1 | Cyclin-dependent kinase 5 activator. (310 aa) |
| | Plk5 | Serine/threonine-protein kinase PLK. (458 aa) |
| | Brca1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (79 aa) |
| | Ing5 | Inhibitor of growth protein. (213 aa) |
| | ENSDORP00000019733 | annotation not available (100 aa) |
| | ENSDORP00000019560 | annotation not available (89 aa) |
| | Zfp385c | Zinc finger protein 385C. (433 aa) |
| | Tp53inp2 | Tumor protein p53-inducible nuclear protein 2 isoform X1. (221 aa) |
| | Phf20 | PHD finger protein 20 isoform X1. (1003 aa) |
| | Csnk2a1 | Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa) |
| | Rictor | Rapamycin-insensitive companion of mTOR. (1631 aa) |
| | Sgk1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (445 aa) |
| | Rfc3 | Replication factor C subunit 3. (366 aa) |
| | Gatad2a | Transcriptional repressor p66-alpha isoform X1. (623 aa) |
| | ENSDORP00000018543 | annotation not available (129 aa) |
| | LOC105996339 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | ENSDORP00000018243 | annotation not available (251 aa) |
| | Ehmt2 | Histone-lysine N-methyltransferase EHMT2. (994 aa) |
| | Tp63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | Pip4k2c | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (421 aa) |
| | Rbbp4 | Histone-binding protein RBBP4. (425 aa) |
| | Tpx2 | Targeting protein for Xklp2. (587 aa) |
| | Prkag3 | 5'-AMP-activated protein kinase subunit gamma-3. (490 aa) |
| | Foxp4 | Forkhead box protein P4 isoform X2. (883 aa) |
| | Chd5 | chromodomain-helicase-DNA-binding protein 5. (1928 aa) |
| | Brpf1 | Peregrin isoform X1. (1253 aa) |
| | Pip4p1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (283 aa) |
| | Aire | Autoimmune regulator. (407 aa) |
| | Taf9b | TATA-box binding protein associated factor 9b. (80 aa) |
| | Rmi1 | recQ-mediated genome instability protein 1. (616 aa) |
| | Cdk2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | Rbbp8 | DNA endonuclease RBBP8. (75 aa) |
| | L3mbtl3 | Lethal(3)malignant brain tumor-like protein 3 isoform X1. (786 aa) |
| | Smyd2 | N-lysine methyltransferase SMYD2. (415 aa) |
| | Atrip | ATR-interacting protein-like. (602 aa) |
| | ENSDORP00000015336 | annotation not available (189 aa) |
| | LOC105991297 | Transcription initiation factor TFIID subunit 11 pseudogene. (204 aa) |
| | Ing2 | Inhibitor of growth protein. (174 aa) |
| | Exd2 | Exonuclease 3'-5' domain-containing protein 2 isoform X2. (631 aa) |
| | Exo1 | Exonuclease 1. (837 aa) |
| | Taf12 | Transcription initiation factor TFIID subunit 12. (176 aa) |
| | Ehmt1 | Histone-lysine N-methyltransferase EHMT1 isoform X1. (566 aa) |
| | Tp73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (638 aa) |
| | Taf15 | TATA-binding protein-associated factor 2N. (528 aa) |
| | Taf1 | Transcription initiation factor TFIID subunit. (1831 aa) |
| | Taf4b | LOW QUALITY PROTEIN: transcription initiation factor TFIID subunit 4B. (842 aa) |
| | Nuak1 | NUAK family SNF1-like kinase 1. (667 aa) |
| | Ppp2r1a | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa) |
| | Ccng1 | cyclin-G1; Belongs to the cyclin family. (295 aa) |
| | Prdm1 | PR domain zinc finger protein 1 isoform X1. (860 aa) |
| | Prkaa1 | Non-specific serine/threonine protein kinase. (538 aa) |
| | Csnk2b | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa) |
| | Trp53bp2 | Apoptosis-stimulating of p53 protein 2. (1123 aa) |
| | Daxx | Death domain-associated protein 6 isoform X1. (745 aa) |
| | Noc2l | Nucleolar complex protein 2 homolog isoform X2. (718 aa) |
| | Banp | Protein BANP isoform X4. (508 aa) |
| | Atm | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | Kat6a | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (886 aa) |
| | Gatad2b | Transcriptional repressor p66-beta isoform X1. (593 aa) |
| | Rffl | E3 ubiquitin-protein ligase rififylin isoform X1. (366 aa) |
| | Hdac2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | Nuak2 | NUAK family SNF1-like kinase 2 isoform X2. (632 aa) |
| | L3mbtl4 | Lethal(3)malignant brain tumor-like protein 4. (610 aa) |
| | Meiob | Meiosis-specific with OB domain-containing protein. (419 aa) |
| | Kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | Usp7 | Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (891 aa) |
| | Pou4f1 | POU domain, class 4, transcription factor 1. (243 aa) |
| | Rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (389 aa) |
| | Rfc2 | Replication factor C subunit 2. (324 aa) |
| | Zfp385b | Zinc finger protein 385B isoform X2. (451 aa) |
| | Pdpk1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa) |
| | Tp53rk | TP53-regulating kinase. (237 aa) |
| | Taf2 | Transcription initiation factor TFIID subunit 2. (1094 aa) |
| | Rfc5 | Replication factor C subunit 5. (332 aa) |
| | Hipk4 | Homeodomain-interacting protein kinase 4. (409 aa) |
| | Dyrk3 | Dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1. (587 aa) |
| | Blm | Bloom syndrome protein isoform X1. (1034 aa) |
| | Mapkapk5 | MAP kinase-activated protein kinase 5 isoform X1. (478 aa) |
| | Chd3 | chromodomain-helicase-DNA-binding protein 3. (1964 aa) |
| | Brd7 | Bromodomain-containing protein 7. (652 aa) |
| | Taf5 | Transcription initiation factor TFIID subunit 5. (706 aa) |
| | Ep300 | Histone acetyltransferase p300. (2345 aa) |
| | Topbp1 | DNA topoisomerase 2-binding protein 1 isoform X1. (130 aa) |
| | Pip4k2b | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta. (400 aa) |
| | Prkaa2 | Non-specific serine/threonine protein kinase. (549 aa) |
| | Aurkb | Aurora kinase B isoform X1; Belongs to the protein kinase superfamily. (343 aa) |
| | Rad1 | Cell cycle checkpoint protein RAD1 isoform X2. (281 aa) |
| | Taf11 | Transcription initiation factor TFIID subunit 11 isoform X1. (211 aa) |
| | Brip1 | LOW QUALITY PROTEIN: Fanconi anemia group J protein. (948 aa) |
| | Pml | Protein PML isoform X1. (830 aa) |
| | Chek2 | Serine/threonine-protein kinase Chk2. (467 aa) |
| | Supt16h | FACT complex subunit SPT16. (1047 aa) |
| | Setd9 | SET domain-containing protein 9 isoform X1. (285 aa) |
| | Ppp2r1b | Protein phosphatase 2 scaffold subunit Abeta. (584 aa) |
| | Ssrp1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | Dna2 | DNA replication ATP-dependent helicase/nuclease DNA2. (1044 aa) |
| | Hipk3 | Homeodomain-interacting protein kinase 3. (1093 aa) |
| | Aurka | Aurora kinase A; Belongs to the protein kinase superfamily. (415 aa) |
| | Prkag2 | 5'-AMP-activated protein kinase subunit gamma-2. (191 aa) |
| | Brd1 | Bromodomain-containing protein 1 isoform X1. (1188 aa) |
| | Ppp1r13l | relA-associated inhibitor. (828 aa) |
| | Ppp2cb | Serine/threonine-protein phosphatase. (309 aa) |
| | Ccna2 | cyclin-A2; Belongs to the cyclin family. (425 aa) |
| | Taf3 | Transcription initiation factor TFIID subunit 3. (928 aa) |
| | Mdm2 | E3 ubiquitin-protein ligase Mdm2. (446 aa) |
| | Mdm4 | Protein Mdm4. (481 aa) |
| | Taf4 | Transcription initiation factor TFIID subunit 4. (635 aa) |
| | Rnf34 | E3 ubiquitin-protein ligase RNF34. (383 aa) |
| | Hus1 | Checkpoint protein; Belongs to the HUS1 family. (267 aa) |
| | Cdk5 | Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa) |
| | Pin1 | Peptidyl-prolyl cis-trans isomerase. (165 aa) |
| | Rps27a | ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | Akt1 | Non-specific serine/threonine protein kinase. (188 aa) |
| | Plk3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | Jmy | Junction-mediating and -regulatory protein. (985 aa) |
| | Top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1004 aa) |
| | Prmt5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | Mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (203 aa) |
| | Brpf3 | Bromodomain and PHD finger containing 3. (140 aa) |
| | Mbd3 | methyl-CpG-binding domain protein 3 isoform X2. (254 aa) |
| | Txndc11 | Thioredoxin domain-containing protein 11 isoform X1. (858 aa) |
| | Slf1 | Ankyrin repeat domain-containing protein 32 isoform X1. (1055 aa) |
| | Cdk3 | Cyclin-dependent kinase 3 isoform X1; Belongs to the protein kinase superfamily. (305 aa) |
| | Pou4f2 | POU domain protein. (348 aa) |
| | Mta2 | Metastasis-associated protein MTA2. (561 aa) |
| | Mtor | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa) |
| | Hdac1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (477 aa) |
| | Taf9 | Transcription initiation factor TFIID subunit 9. (263 aa) |
| | Rad17 | Cell cycle checkpoint protein RAD17. (640 aa) |
| | Atr | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2592 aa) |
| | Stk11 | Serine/threonine-protein kinase STK11 isoform X1; Belongs to the protein kinase superfamily. (310 aa) |
| | Taf10 | Transcription initiation factor TFIID subunit 10. (180 aa) |
| | Hipk2 | Homeodomain-interacting protein kinase 2 isoform X1. (1196 aa) |
| | Rbbp7 | Histone-binding protein RBBP7. (416 aa) |
| | Taf6 | Transcription initiation factor TFIID subunit 6. (677 aa) |
| | Ccna1 | cyclin-A1; Belongs to the cyclin family. (420 aa) |
| | Kmt5a | N-lysine methyltransferase SETD8. (341 aa) |
| | Csnk2a2 | Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | Pip4k2a | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha. (405 aa) |
| | Ubc | polyubiquitin-C. (153 aa) |
| | Recql4 | ATP-dependent DNA helicase Q4 isoform X2. (1189 aa) |
| | Wrn | Werner syndrome ATP-dependent helicase. (1377 aa) |
| | L3mbtl1 | Lethal(3)malignant brain tumor-like protein 1. (833 aa) |
| | Pou4f3 | POU domain protein. (339 aa) |
| | Brd9 | Bromodomain-containing protein 9 isoform X2. (597 aa) |
