STRINGSTRING
Fn1 Fn1 Sh3kbp1 Sh3kbp1 Ptpn1 Ptpn1 Rab4a Rab4a Stat3 Stat3 Ptpn2 Ptpn2 Gga3 Gga3 Arf6 Arf6 Nras Nras Crk Crk Uba52 Uba52 Hpn Hpn Hgs Hgs Kras Kras Crkl Crkl LOC105993014 LOC105993014 LOC105990085 LOC105990085 Cbl Cbl ENSDORP00000020231 ENSDORP00000020231 Lama2 Lama2 Pik3r1 Pik3r1 Met Met Ptk2 Ptk2 ENSDORP00000019733 ENSDORP00000019733 Lrig1 Lrig1 Hgf Hgf Tns1 Tns1 Rap1b Rap1b Usp8 Usp8 Stam2 Stam2 Col5a2 Col5a2 Megf11 Megf11 Col3a1 Col3a1 Lama5 Lama5 Tns4 Tns4 Gab1 Gab1 Col24a1 Col24a1 Eps15 Eps15 Hgfac Hgfac Lamc2 Lamc2 Lamc3 Lamc3 Rac1 Rac1 Col5a3 Col5a3 Sh3gl3 Sh3gl3 Col11a2 Col11a2 Col1a1 Col1a1 Itga3 Itga3 Col27a1 Col27a1 Ptpn11 Ptpn11 Stam Stam Sh3gl1 Sh3gl1 Pik3ca Pik3ca Ranbp10 Ranbp10 Lama1 Lama1 Kras-2 Kras-2 Csde1 Csde1 Rap1a Rap1a Col11a1 Col11a1 Col2a1 Col2a1 Lama4 Lama4 Sos1 Sos1 Col1a2 Col1a2 Tns3 Tns3 Rapgef1 Rapgef1 Shc1 Shc1 Ranbp9 Ranbp9 Rps27a Rps27a Rab4b Rab4b Col5a1 Col5a1 Lama3 Lama3 Lamb2 Lamb2 Itgb1 Itgb1 Lamc1 Lamc1 Itga2 Itga2 Lamb1 Lamb1 Sh3gl2 Sh3gl2 Fndc3a Fndc3a Grb2 Grb2 Dock7 Dock7 Lamb3 Lamb3 ENSDORP00000026363 ENSDORP00000026363 ENSDORP00000026359 ENSDORP00000026359 Ptprj Ptprj Hras Hras
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fn1Fibronectin. (321 aa)
Sh3kbp1SH3 domain-containing kinase-binding protein 1 isoform X5. (707 aa)
Ptpn1Tyrosine-protein phosphatase non-receptor type. (436 aa)
Rab4aRas-related protein Rab-4A isoform X1. (218 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Ptpn2Tyrosine-protein phosphatase non-receptor type 2. (397 aa)
Gga3ADP-ribosylation factor-binding protein GGA3 isoform X1. (114 aa)
Arf6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
NrasGTPase NRas. (189 aa)
CrkAdapter molecule crk. (304 aa)
Uba52ubiquitin-60S ribosomal protein L40. (128 aa)
HpnSerine protease hepsin isoform X2; Belongs to the peptidase S1 family. (416 aa)
HgsHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (775 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
CrklCrk-like protein. (303 aa)
LOC105993014ubiquitin-40S ribosomal protein S27a pseudogene. (147 aa)
LOC105990085Tyrosine-protein phosphatase non-receptor type. (333 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
ENSDORP00000020231annotation not available (517 aa)
Lama2Laminin subunit alpha-2. (3099 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
MetHepatocyte growth factor receptor. (1382 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
ENSDORP00000019733annotation not available (100 aa)
Lrig1Leucine-rich repeats and immunoglobulin-like domains protein 1. (1035 aa)
HgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
Tns1Tensin-1 isoform X3. (1790 aa)
Rap1bRas-related protein Rap-1b. (184 aa)
Usp8Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1018 aa)
Stam2Signal transducing adapter molecule 2 isoform X1. (521 aa)
Col5a2Collagen alpha-2(V) chain. (1481 aa)
Megf11Multiple epidermal growth factor-like domains protein 11. (1106 aa)
Col3a1Collagen alpha-1(III) chain. (1437 aa)
Lama5Laminin subunit alpha-5. (3481 aa)
Tns4Tensin-4. (664 aa)
Gab1GRB2-associated-binding protein 1. (707 aa)
Col24a1Collagen alpha-1(XXIV) chain. (1684 aa)
Eps15Epidermal growth factor receptor substrate 15. (880 aa)
HgfacHepatocyte growth factor activator isoform X1. (650 aa)
Lamc2Laminin subunit gamma-2. (1183 aa)
Lamc3Laminin subunit gamma-3. (1286 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
Col5a3Collagen alpha-3(V) chain. (1447 aa)
Sh3gl3endophilin-A3. (346 aa)
Col11a2Collagen alpha-2(XI) chain isoform X1. (1689 aa)
Col1a1Collagen alpha-1(I) chain. (1285 aa)
Itga3Integrin alpha-3; Belongs to the integrin alpha chain family. (1050 aa)
Col27a1Collagen alpha-1(XXVII) chain. (1755 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
StamSignal transducing adapter molecule 1. (538 aa)
Sh3gl1endophilin-A2. (367 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Ranbp10Ran-binding protein 10. (628 aa)
Lama1Laminin subunit alpha-1. (3037 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Rap1aRas-related protein Rap-1A. (178 aa)
Col11a1Collagen alpha-1(XI) chain isoform X2. (1762 aa)
Col2a1Collagen alpha-1(II) chain isoform X2. (1487 aa)
Lama4Laminin subunit alpha-4. (1819 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Col1a2Collagen alpha-2(I) chain. (1364 aa)
Tns3Tensin-3 isoform X1. (1444 aa)
Rapgef1Rap guanine nucleotide exchange factor 1 isoform X1. (1198 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Ranbp9Ran-binding protein 9. (685 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Rab4bRas-related protein Rab-4B. (213 aa)
Col5a1Collagen alpha-1(V) chain. (1806 aa)
Lama3Laminin subunit alpha-3. (1719 aa)
Lamb2Laminin subunit beta-2. (1800 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Lamc1Laminin subunit gamma-1. (1563 aa)
Itga2Integrin alpha-2; Belongs to the integrin alpha chain family. (1167 aa)
Lamb1Laminin subunit beta-1. (1815 aa)
Sh3gl2endophilin-A1. (346 aa)
Fndc3aFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Dock7Dedicator of cytokinesis protein 7; Belongs to the DOCK family. (2124 aa)
Lamb3Laminin subunit beta-3. (1172 aa)
ENSDORP00000026363annotation not available (164 aa)
ENSDORP00000026359annotation not available (202 aa)
PtprjReceptor-type tyrosine-protein phosphatase eta. (1205 aa)
HrasGTPase HRas isoform X1. (192 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.