8 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Grb2	Growth factor receptor-bound protein 2. (217 aa)
	Sos1	Son of sevenless homolog 1. (1301 aa)
	Mapk3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
	Shc1	SHC-transforming protein 1 isoform X2. (473 aa)
	Irs1	Insulin receptor substrate 1. (1239 aa)
	Grb10	Growth factor receptor-bound protein 10 isoform X2. (541 aa)
	Mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	Ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (102 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Grb10	Grb2	ENSDORP00000014594	ENSDORP00000027785	Growth factor receptor-bound protein 10 isoform X2.	Growth factor receptor-bound protein 2.	0.718
Grb10	Ins	ENSDORP00000014594	ENSDORP00000021608	Growth factor receptor-bound protein 10 isoform X2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.630
Grb10	Irs1	ENSDORP00000014594	ENSDORP00000011617	Growth factor receptor-bound protein 10 isoform X2.	Insulin receptor substrate 1.	0.697
Grb10	Mapk1	ENSDORP00000014594	ENSDORP00000016925	Growth factor receptor-bound protein 10 isoform X2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.414
Grb10	Mapk3	ENSDORP00000014594	ENSDORP00000003152	Growth factor receptor-bound protein 10 isoform X2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.414
Grb10	Shc1	ENSDORP00000014594	ENSDORP00000003514	Growth factor receptor-bound protein 10 isoform X2.	SHC-transforming protein 1 isoform X2.	0.579
Grb10	Sos1	ENSDORP00000014594	ENSDORP00000002200	Growth factor receptor-bound protein 10 isoform X2.	Son of sevenless homolog 1.	0.494
Grb2	Grb10	ENSDORP00000027785	ENSDORP00000014594	Growth factor receptor-bound protein 2.	Growth factor receptor-bound protein 10 isoform X2.	0.718
Grb2	Ins	ENSDORP00000027785	ENSDORP00000021608	Growth factor receptor-bound protein 2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.726
Grb2	Irs1	ENSDORP00000027785	ENSDORP00000011617	Growth factor receptor-bound protein 2.	Insulin receptor substrate 1.	0.990
Grb2	Mapk1	ENSDORP00000027785	ENSDORP00000016925	Growth factor receptor-bound protein 2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.567
Grb2	Mapk3	ENSDORP00000027785	ENSDORP00000003152	Growth factor receptor-bound protein 2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.567
Grb2	Shc1	ENSDORP00000027785	ENSDORP00000003514	Growth factor receptor-bound protein 2.	SHC-transforming protein 1 isoform X2.	0.999
Grb2	Sos1	ENSDORP00000027785	ENSDORP00000002200	Growth factor receptor-bound protein 2.	Son of sevenless homolog 1.	0.997
Ins	Grb10	ENSDORP00000021608	ENSDORP00000014594	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor-bound protein 10 isoform X2.	0.630
Ins	Grb2	ENSDORP00000021608	ENSDORP00000027785	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor-bound protein 2.	0.726
Ins	Irs1	ENSDORP00000021608	ENSDORP00000011617	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin receptor substrate 1.	0.849
Ins	Shc1	ENSDORP00000021608	ENSDORP00000003514	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	SHC-transforming protein 1 isoform X2.	0.634
Ins	Sos1	ENSDORP00000021608	ENSDORP00000002200	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Son of sevenless homolog 1.	0.560
Irs1	Grb10	ENSDORP00000011617	ENSDORP00000014594	Insulin receptor substrate 1.	Growth factor receptor-bound protein 10 isoform X2.	0.697