47 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tln1	Talin-1 isoform X2. (2541 aa)
	Raph1	Ras-associated and pleckstrin homology domains-containing protein 1. (668 aa)
	Cass4	Cas scaffolding protein family member 4. (743 aa)
	Rapgef5	Rap guanine nucleotide exchange factor 5. (584 aa)
	Thpo	Thrombopoietin. (136 aa)
	Fgg	Fibrinogen gamma chain. (437 aa)
	Fga	Fibrinogen alpha chain. (771 aa)
	Apbb1ip	Amyloid beta A4 precursor protein-binding family B member 1-interacting protein. (510 aa)
	Fgb	Fibrinogen beta chain. (477 aa)
	ENSDORP00000016186	annotation not available (386 aa)
	Adra2c	alpha-2C adrenergic receptor. (305 aa)
	Adra2a	alpha-2A adrenergic receptor. (340 aa)
	Gp9	Platelet glycoprotein IX. (178 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (619 aa)
	Rap1b	Ras-related protein Rap-1b. (184 aa)
	Grb2	Growth factor receptor-bound protein 2. (217 aa)
	Mpl	Thrombopoietin receptor. (521 aa)
	Rapgef3	Rap guanine nucleotide exchange factor 3. (216 aa)
	Itgb3	Integrin beta; Belongs to the integrin beta chain family. (766 aa)
	Rasgrp2	RAS guanyl-releasing protein 2 isoform X2. (231 aa)
	Gp1bb	Platelet glycoprotein Ib beta chain. (215 aa)
	Col1a1	Collagen alpha-1(I) chain. (1285 aa)
	Csk	Tyrosine-protein kinase. (450 aa)
	Pdpk1	3-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
	Bcar1	Breast cancer anti-estrogen resistance protein 1 isoform X1. (931 aa)
	Rap1a	Ras-related protein Rap-1A. (178 aa)
	Ptk2	Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
	Crk	Adapter molecule crk. (304 aa)
	Nedd9	Enhancer of filamentation 1 isoform X3. (834 aa)
	Ptpn1	Tyrosine-protein phosphatase non-receptor type. (436 aa)
	Lrrc15	Leucine-rich repeat-containing protein 15. (577 aa)
	Rasgrp1	RAS guanyl-releasing protein 1. (763 aa)
	Adra2b	alpha-2B adrenergic receptor isoform X1. (451 aa)
	Fn1	Fibronectin. (321 aa)
	ENSDORP00000026359	annotation not available (202 aa)
	ENSDORP00000026363	annotation not available (164 aa)
	Fndc3a	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	Syk	Tyrosine-protein kinase. (633 aa)
	Mfsd8	Major facilitator superfamily domain-containing protein 8 isoform X1. (507 aa)
	Tln2	Talin-2. (2513 aa)
	Sos1	Son of sevenless homolog 1. (1301 aa)
	Col1a2	Collagen alpha-2(I) chain. (1364 aa)
	Shc1	SHC-transforming protein 1 isoform X2. (473 aa)
	Rapgef4	Rap guanine nucleotide exchange factor 4 isoform X1. (838 aa)
	Itga2b	Integrin alpha-IIb; Belongs to the integrin alpha chain family. (891 aa)
	Akt1	Non-specific serine/threonine protein kinase. (188 aa)
	Rapgefl1	LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor-like 1. (648 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adra2a	Adra2b	ENSDORP00000017649	ENSDORP00000025113	alpha-2A adrenergic receptor.	alpha-2B adrenergic receptor isoform X1.	0.597
Adra2b	Adra2a	ENSDORP00000025113	ENSDORP00000017649	alpha-2B adrenergic receptor isoform X1.	alpha-2A adrenergic receptor.	0.597
Adra2b	Adra2c	ENSDORP00000025113	ENSDORP00000019701	alpha-2B adrenergic receptor isoform X1.	alpha-2C adrenergic receptor.	0.502
Adra2c	Adra2b	ENSDORP00000019701	ENSDORP00000025113	alpha-2C adrenergic receptor.	alpha-2B adrenergic receptor isoform X1.	0.502
Akt1	Apbb1ip	ENSDORP00000005559	ENSDORP00000009032	Non-specific serine/threonine protein kinase.	Amyloid beta A4 precursor protein-binding family B member 1-interacting protein.	0.423
Akt1	Bcar1	ENSDORP00000005559	ENSDORP00000026955	Non-specific serine/threonine protein kinase.	Breast cancer anti-estrogen resistance protein 1 isoform X1.	0.554
Akt1	Col1a1	ENSDORP00000005559	ENSDORP00000012701	Non-specific serine/threonine protein kinase.	Collagen alpha-1(I) chain.	0.435
Akt1	Crk	ENSDORP00000005559	ENSDORP00000022183	Non-specific serine/threonine protein kinase.	Adapter molecule crk.	0.651
Akt1	Csk	ENSDORP00000005559	ENSDORP00000012231	Non-specific serine/threonine protein kinase.	Tyrosine-protein kinase.	0.644
Akt1	ENSDORP00000026363	ENSDORP00000005559	ENSDORP00000026363	Non-specific serine/threonine protein kinase.	annotation not available	0.571
Akt1	F2	ENSDORP00000005559	ENSDORP00000018416	Non-specific serine/threonine protein kinase.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.460
Akt1	Grb2	ENSDORP00000005559	ENSDORP00000027785	Non-specific serine/threonine protein kinase.	Growth factor receptor-bound protein 2.	0.750
Akt1	Itga2b	ENSDORP00000005559	ENSDORP00000005405	Non-specific serine/threonine protein kinase.	Integrin alpha-IIb; Belongs to the integrin alpha chain family.	0.493
Akt1	Itgb3	ENSDORP00000005559	ENSDORP00000015441	Non-specific serine/threonine protein kinase.	Integrin beta; Belongs to the integrin beta chain family.	0.578
Akt1	Nedd9	ENSDORP00000005559	ENSDORP00000022789	Non-specific serine/threonine protein kinase.	Enhancer of filamentation 1 isoform X3.	0.404
Akt1	Pdpk1	ENSDORP00000005559	ENSDORP00000011222	Non-specific serine/threonine protein kinase.	3-phosphoinositide-dependent protein kinase 1 isoform X1.	0.992
Akt1	Ptk2	ENSDORP00000005559	ENSDORP00000019796	Non-specific serine/threonine protein kinase.	Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.793
Akt1	Ptpn1	ENSDORP00000005559	ENSDORP00000024749	Non-specific serine/threonine protein kinase.	Tyrosine-protein phosphatase non-receptor type.	0.533
Akt1	Rap1a	ENSDORP00000005559	ENSDORP00000010956	Non-specific serine/threonine protein kinase.	Ras-related protein Rap-1A.	0.631
Akt1	Rap1b	ENSDORP00000005559	ENSDORP00000018744	Non-specific serine/threonine protein kinase.	Ras-related protein Rap-1b.	0.571