27 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	P4hb	Protein disulfide-isomerase. (485 aa)
	Apoc2	Apolipoprotein C-II. (100 aa)
	Lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (474 aa)
	Pltp	Phospholipid transfer protein. (496 aa)
	Pcsk4	Proprotein convertase subtilisin/kexin type 4. (432 aa)
	Plg	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (809 aa)
	Abcg1	ATP-binding cassette sub-family G member 1. (672 aa)
	Apob	Apolipoprotein B-100. (4414 aa)
	Pcsk6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (927 aa)
	Apoa4	Apolipoprotein A-IV. (394 aa)
	Lipg	Endothelial lipase. (509 aa)
	Lmf2	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (697 aa)
	Furin	Furin; Belongs to the peptidase S8 family. (790 aa)
	Apoa5	Apolipoprotein A-V. (373 aa)
	Apoc3	Apolipoprotein C-III isoform X2. (129 aa)
	Apoa1	Apolipoprotein A-I. (267 aa)
	Mttp	Microsomal triglyceride transfer protein large subunit. (908 aa)
	Gpihbp1	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1. (205 aa)
	Angptl3	Angiopoietin-related protein 3. (454 aa)
	Pdia2	Protein disulfide-isomerase A2. (518 aa)
	Angptl4	Angiopoietin-related protein 4. (382 aa)
	Angptl8	Angiopoietin-like protein 8. (198 aa)
	Pcsk5	Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (912 aa)
	Apoe	Apolipoprotein E. (274 aa)
	Lcat	Phosphatidylcholine-sterol acyltransferase. (427 aa)
	Alb	Serum albumin-like. (607 aa)
	Apoa2	Apolipoprotein A-II. (101 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abcg1	Apoa1	ENSDORP00000020266	ENSDORP00000011659	ATP-binding cassette sub-family G member 1.	Apolipoprotein A-I.	0.447
Abcg1	Apoa2	ENSDORP00000020266	ENSDORP00000001588	ATP-binding cassette sub-family G member 1.	Apolipoprotein A-II.	0.426
Abcg1	Apoe	ENSDORP00000020266	ENSDORP00000003348	ATP-binding cassette sub-family G member 1.	Apolipoprotein E.	0.538
Alb	Apoa2	ENSDORP00000002639	ENSDORP00000001588	Serum albumin-like.	Apolipoprotein A-II.	0.860
Alb	Apoa4	ENSDORP00000002639	ENSDORP00000016073	Serum albumin-like.	Apolipoprotein A-IV.	0.420
Alb	Apob	ENSDORP00000002639	ENSDORP00000018366	Serum albumin-like.	Apolipoprotein B-100.	0.680
Alb	Apoc3	ENSDORP00000002639	ENSDORP00000011660	Serum albumin-like.	Apolipoprotein C-III isoform X2.	0.650
Alb	Apoe	ENSDORP00000002639	ENSDORP00000003348	Serum albumin-like.	Apolipoprotein E.	0.591
Alb	Lcat	ENSDORP00000002639	ENSDORP00000002663	Serum albumin-like.	Phosphatidylcholine-sterol acyltransferase.	0.560
Alb	Plg	ENSDORP00000002639	ENSDORP00000020772	Serum albumin-like.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.906
Angptl3	Angptl4	ENSDORP00000007768	ENSDORP00000006731	Angiopoietin-related protein 3.	Angiopoietin-related protein 4.	0.851
Angptl3	Angptl8	ENSDORP00000007768	ENSDORP00000006420	Angiopoietin-related protein 3.	Angiopoietin-like protein 8.	0.944
Angptl3	Apoa5	ENSDORP00000007768	ENSDORP00000011662	Angiopoietin-related protein 3.	Apolipoprotein A-V.	0.682
Angptl3	Apob	ENSDORP00000007768	ENSDORP00000018366	Angiopoietin-related protein 3.	Apolipoprotein B-100.	0.596
Angptl3	Apoc3	ENSDORP00000007768	ENSDORP00000011660	Angiopoietin-related protein 3.	Apolipoprotein C-III isoform X2.	0.474
Angptl3	Gpihbp1	ENSDORP00000007768	ENSDORP00000010735	Angiopoietin-related protein 3.	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1.	0.662
Angptl3	Lipg	ENSDORP00000007768	ENSDORP00000014261	Angiopoietin-related protein 3.	Endothelial lipase.	0.403
Angptl3	Lpl	ENSDORP00000007768	ENSDORP00000023751	Angiopoietin-related protein 3.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.937
Angptl3	Plg	ENSDORP00000007768	ENSDORP00000020772	Angiopoietin-related protein 3.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.509
Angptl4	Angptl3	ENSDORP00000006731	ENSDORP00000007768	Angiopoietin-related protein 4.	Angiopoietin-related protein 3.	0.851