STRINGSTRING
Itgb5 Itgb5 Inhbb Inhbb Pard6a Pard6a Hdac1 Hdac1 Bmpr1b Bmpr1b Itgb8 Itgb8 Pard3 Pard3 Smurf1 Smurf1 Tfdp1 Tfdp1 Inhba Inhba Mtmr4 Mtmr4 Ubc Ubc Fst Fst Zfyve16 Zfyve16 Smad9 Smad9 Ccnt1 Ccnt1 Mapk3 Mapk3 Tgfb1 Tgfb1 Tgfb2 Tgfb2 Grem2 Grem2 Smad5 Smad5 Skil Skil Parp1 Parp1 Trim33 Trim33 Itgb6 Itgb6 Chrdl2 Chrdl2 Ncor2 Ncor2 Irx5 Irx5 Itga8 Itga8 Rps27a Rps27a Stub1 Stub1 Rnf111 Rnf111 Cgn Cgn Arhgef18 Arhgef18 Ppm1a Ppm1a Itgb1 Itgb1 Smad1 Smad1 Meis3 Meis3 F11r F11r Acvr2b Acvr2b Smad4 Smad4 Bmpr2 Bmpr2 Bmpr1a Bmpr1a Drap1 Drap1 Acvr1c Acvr1c Atp1b4 Atp1b4 Fbn1 Fbn1 Mkx Mkx Bmp2 Bmp2 Amhr2 Amhr2 Cdk8 Cdk8 E2f5 E2f5 Bambi Bambi Chrdl1 Chrdl1 Irx3 Irx3 Irx6 Irx6 ENSDORP00000011621 ENSDORP00000011621 Snw1 Snw1 Ncor1 Ncor1 Bmp10 Bmp10 Tgfb3 Tgfb3 Zcchc4 Zcchc4 Cdk9 Cdk9 Acvr1 Acvr1 Ltbp1 Ltbp1 Furin Furin Pard3b Pard3b Amh Amh Acvr2a Acvr2a Cer1 Cer1 Foxh1 Foxh1 Tgfbr2 Tgfbr2 E2f4 E2f4 Irx4 Irx4 Acvrl1 Acvrl1 Itgb3 Itgb3 Nedd4l Nedd4l ENSDORP00000015911 ENSDORP00000015911 Sp1 Sp1 Usp9x Usp9x Ccnq Ccnq Rbl1 Rbl1 Mapk1 Mapk1 Tgif1 Tgif1 Ccnt2 Ccnt2 Fstl1 Fstl1 Ltbp2 Ltbp2 Fkbp1a Fkbp1a Gdf2 Gdf2 Fstl3 Fstl3 Ppp1r15a Ppp1r15a Tfdp2 Tfdp2 Smad2 Smad2 Rhoa Rhoa Itgav Itgav Ltbp4 Ltbp4 Tgfbr1 Tgfbr1 ENSDORP00000019733 ENSDORP00000019733 Tgif2 Tgif2 ENSDORP00000020209 ENSDORP00000020209 Ube2d1 Ube2d1 Cbl Cbl ENSDORP00000020542 ENSDORP00000020542 Kxd1 Kxd1 LOC105993014 LOC105993014 Pcsk4 Pcsk4 Acvr1b Acvr1b Uba52 Uba52 LOC105986631 LOC105986631 Ubb Ubb ENSDORP00000022774 ENSDORP00000022774 ENSDORP00000022835 ENSDORP00000022835 Smad3 Smad3 ENSDORP00000023286 ENSDORP00000023286 Ube2m Ube2m Strap Strap Smurf2 Smurf2 Smad6 Smad6 Ldlrad4 Ldlrad4 ENSDORP00000025611 ENSDORP00000025611 Ski Ski Nog Nog Nedd8 Nedd8 Zfyve9 Zfyve9 Ccnk Ccnk Ltbp3 Ltbp3 Men1 Men1 Smad7 Smad7 Ccnc Ccnc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Itgb5Integrin beta; Belongs to the integrin beta chain family. (739 aa)
InhbbInhibin beta B chain. (659 aa)
Pard6aPartitioning defective 6 homolog alpha. (345 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (477 aa)
Bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
Itgb8Integrin beta; Belongs to the integrin beta chain family. (737 aa)
Pard3Partitioning defective 3 homolog isoform X1. (1294 aa)
Smurf1E3 ubiquitin-protein ligase SMURF1. (689 aa)
Tfdp1Transcription factor. (410 aa)
InhbaInhibin beta A chain. (133 aa)
Mtmr4Myotubularin-related protein 4 isoform X1. (204 aa)
Ubcpolyubiquitin-C. (153 aa)
FstFollistatin isoform X1. (344 aa)
Zfyve16Zinc finger FYVE domain-containing protein. (1528 aa)
Smad9Mothers against decapentaplegic homolog. (430 aa)
Ccnt1cyclin-T1; Belongs to the cyclin family. (728 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (130 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (443 aa)
Grem2Gremlin-2. (170 aa)
Smad5Mothers against decapentaplegic homolog. (465 aa)
SkilSki-like protein. (674 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1000 aa)
Trim33E3 ubiquitin-protein ligase TRIM33. (1061 aa)
Itgb6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
Chrdl2Chordin-like protein 2 isoform X2. (427 aa)
Ncor2Nuclear receptor corepressor 2. (2240 aa)
Irx5Iroquois-class homeodomain protein IRX-5 isoform X1. (513 aa)
Itga8Integrin alpha-8; Belongs to the integrin alpha chain family. (1063 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Stub1E3 ubiquitin-protein ligase CHIP. (267 aa)
Rnf111E3 ubiquitin-protein ligase Arkadia isoform X3. (991 aa)
CgnCingulin. (1109 aa)
Arhgef18Rho guanine nucleotide exchange factor 18. (920 aa)
Ppm1aProtein phosphatase 1A. (382 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Smad1Mothers against decapentaplegic homolog. (465 aa)
Meis3Homeobox protein Meis3 isoform X2. (375 aa)
F11rJunctional adhesion molecule A. (293 aa)
Acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (303 aa)
Smad4Mothers against decapentaplegic homolog. (528 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (933 aa)
Bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Drap1Dr1-associated corepressor. (185 aa)
Acvr1cReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (363 aa)
Atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (359 aa)
Fbn1Fibrillin-1. (2873 aa)
MkxHomeobox protein Mohawk. (351 aa)
Bmp2Bone morphogenetic protein 2. (398 aa)
Amhr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (569 aa)
Cdk8Cyclin-dependent kinase 8. (399 aa)
E2f5Transcription factor E2F5 isoform X1. (352 aa)
BambiBMP and activin membrane-bound inhibitor homolog. (251 aa)
Chrdl1Chordin-like protein 1 isoform X2. (450 aa)
Irx3Iroquois-class homeodomain protein IRX-3. (505 aa)
Irx6Iroquois-class homeodomain protein IRX-6. (443 aa)
ENSDORP00000011621annotation not available (186 aa)
Snw1SNW domain-containing protein 1. (539 aa)
Ncor1Nuclear receptor corepressor 1. (1652 aa)
Bmp10Bone morphogenetic protein 10. (424 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Zcchc4Zinc finger CCHC domain-containing protein 4 isoform X3. (274 aa)
Cdk9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
Ltbp1Latent-transforming growth factor beta-binding protein 1 isoform X1. (1660 aa)
FurinFurin; Belongs to the peptidase S8 family. (790 aa)
Pard3bPartitioning defective 3 homolog B. (872 aa)
AmhMuellerian-inhibiting factor. (547 aa)
Acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
Cer1Cerberus. (272 aa)
Foxh1Forkhead box protein H1. (368 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
E2f4Transcription factor E2F4 isoform X3. (121 aa)
Irx4Iroquois-class homeodomain protein IRX-4. (435 aa)
Acvrl1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (766 aa)
Nedd4lE3 ubiquitin-protein ligase NEDD4-like isoform X1. (984 aa)
ENSDORP00000015911annotation not available (354 aa)
Sp1Transcription factor Sp1. (786 aa)
Usp9xProbable ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2317 aa)
CcnqCyclin-related protein FAM58A isoform X1; Belongs to the cyclin family. (250 aa)
Rbl1Retinoblastoma-like protein 1. (1063 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Tgif1Homeobox protein TGIF1 isoform X1. (270 aa)
Ccnt2cyclin-T2 isoform X3; Belongs to the cyclin family. (169 aa)
Fstl1Follistatin-related protein 1. (306 aa)
Ltbp2Latent-transforming growth factor beta-binding protein 2. (1791 aa)
Fkbp1aPeptidylprolyl isomerase. (108 aa)
Gdf2Growth/differentiation factor 2. (430 aa)
Fstl3Follistatin-related protein 3. (246 aa)
Ppp1r15aProtein phosphatase 1 regulatory subunit 15A. (77 aa)
Tfdp2Transcription factor. (203 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
RhoaTransforming protein RhoA. (193 aa)
ItgavIntegrin alpha-V; Belongs to the integrin alpha chain family. (1047 aa)
Ltbp4Latent-transforming growth factor beta-binding protein 4. (1375 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (490 aa)
ENSDORP00000019733annotation not available (100 aa)
Tgif2Homeobox protein TGIF2. (239 aa)
ENSDORP00000020209annotation not available (294 aa)
Ube2d1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
ENSDORP00000020542annotation not available (55 aa)
Kxd1kxDL motif-containing protein 1 isoform X2. (183 aa)
LOC105993014ubiquitin-40S ribosomal protein S27a pseudogene. (147 aa)
Pcsk4Proprotein convertase subtilisin/kexin type 4. (432 aa)
Acvr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (450 aa)
Uba52ubiquitin-60S ribosomal protein L40. (128 aa)
LOC105986631Ubiquitin-like. (77 aa)
Ubbpolyubiquitin-B. (155 aa)
ENSDORP00000022774annotation not available (389 aa)
ENSDORP00000022835annotation not available (193 aa)
Smad3Mothers against decapentaplegic homolog. (425 aa)
ENSDORP00000023286annotation not available (584 aa)
Ube2mNEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (177 aa)
StrapSerine-threonine kinase receptor-associated protein. (293 aa)
Smurf2E3 ubiquitin-protein ligase SMURF2. (722 aa)
Smad6Mothers against decapentaplegic homolog. (401 aa)
Ldlrad4Low-density lipoprotein receptor class A domain-containing protein 4. (306 aa)
ENSDORP00000025611annotation not available (266 aa)
SkiSki oncogene. (719 aa)
NogNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (233 aa)
Nedd8NEDD8. (81 aa)
Zfyve9Zinc finger FYVE domain-containing protein. (1388 aa)
Ccnkcyclin-K; Belongs to the cyclin family. (579 aa)
Ltbp3Latent-transforming growth factor beta-binding protein 3. (1208 aa)
Men1Menin isoform X2. (610 aa)
Smad7Mothers against decapentaplegic homolog. (427 aa)
CcncLOW QUALITY PROTEIN: cyclin-C. (258 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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