STRINGSTRING
Foxo3 Foxo3 Gnai1 Gnai1 Zdhhc21 Zdhhc21 Sphk1 Sphk1 Cav2 Cav2 Ptk2 Ptk2 Pik3r1 Pik3r1 Kras Kras Xpo1 Xpo1 Esr2 Esr2 Akt2 Akt2 S1pr3 S1pr3 Cav1 Cav1 Akt3 Akt3 Uhmk1 Uhmk1 Egf Egf Cdkn1b Cdkn1b Elk1 Elk1 Mmp7 Mmp7 Strn Strn Shc1 Shc1 Gnat3 Gnat3 Areg Areg Mast3 Mast3 Igf1r Igf1r Strn4 Strn4 Akt1 Akt1 Gnai2 Gnai2 Ereg Ereg Zdhhc7 Zdhhc7 Pik3ca Pik3ca Esr1 Esr1 Kras-2 Kras-2 Csde1 Csde1 Pdpk1 Pdpk1 Hbegf Hbegf Creb1 Creb1 Egfr Egfr Mmp2 Mmp2 Epgn Epgn Gnai3 Gnai3 Mmp3 Mmp3 Strn3 Strn3 Tgfa Tgfa Nras Nras Nos3 Nos3 Gng2 Gng2 Gm5741 Gm5741 Insr Insr Btc Btc Pik3r3 Pik3r3 Prmt8 Prmt8 Hras Hras Wdr64 Wdr64 Prmt1 Prmt1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Foxo3Forkhead box protein O3. (672 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
Sphk1Sphingosine kinase 1. (372 aa)
Cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
Xpo1Exportin-1. (921 aa)
Esr2Estrogen receptor beta. (550 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
S1pr3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Uhmk1Serine/threonine-protein kinase Kist. (419 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (664 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (106 aa)
Elk1ETS domain-containing protein Elk-1. (430 aa)
Mmp7Matrilysin. (267 aa)
StrnStriatin. (771 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Gnat3Guanine nucleotide-binding protein G(T) subunit alpha-3. (354 aa)
AregAmphiregulin. (245 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Igf1rTyrosine-protein kinase receptor. (923 aa)
Strn4Striatin-4. (634 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
EregProepiregulin. (163 aa)
Zdhhc7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (307 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (599 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Pdpk13-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
HbegfProheparin-binding EGF-like growth factor. (206 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
EgfrReceptor protein-tyrosine kinase. (1215 aa)
Mmp272 kDa type IV collagenase. (126 aa)
EpgnEpigen isoform X5. (153 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
Mmp3Stromelysin-1-like. (474 aa)
Strn3Striatin-3. (700 aa)
TgfaProtransforming growth factor alpha. (156 aa)
NrasGTPase NRas. (189 aa)
Nos3Nitric oxide synthase; Produces nitric oxide (NO). (1201 aa)
Gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
Gm5741Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
InsrTyrosine-protein kinase receptor. (1183 aa)
BtcProbetacellulin. (163 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Prmt8Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (362 aa)
HrasGTPase HRas isoform X1. (192 aa)
Wdr64WD repeat-containing protein 64. (1048 aa)
Prmt1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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