STRINGSTRING
Cltc Cltc Wwp2 Wwp2 Stam Stam Iqgap1 Iqgap1 Git2 Git2 Ptk2b Ptk2b Txnl1 Txnl1 Nck1 Nck1 Usp9x Usp9x Epha2 Epha2 Pak1 Pak1 Stam2 Stam2 Sptan1 Sptan1 Myo6 Myo6 Peak1 Peak1 Pik3r1 Pik3r1 Rhou Rhou Hgs Hgs Dlg5 Dlg5 Arhgap31 Arhgap31 Arhgap30 Arhgap30 Macf1 Macf1 ENSDORP00000022680 ENSDORP00000022680 LOC105989352 LOC105989352 Pak2 Pak2 Wdr6 Wdr6 Arhgef7 Arhgef7 Srgap2 Srgap2 Vangl1 Vangl1 Grb2 Grb2 Pard6a Pard6a Depdc1b Depdc1b Sptbn1 Sptbn1 Pak3 Pak3 Nck2 Nck2 Mast3 Mast3 Itsn2 Itsn2 Git1 Git1 Arhgef6 Arhgef6 Dst Dst
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
Wwp2E3 ubiquitin-protein ligase. (869 aa)
StamSignal transducing adapter molecule 1. (538 aa)
Iqgap1Ras GTPase-activating-like protein IQGAP1. (1657 aa)
Git2ARF GTPase-activating protein GIT2 isoform X1. (757 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
Txnl1Thioredoxin-like protein 1 isoform X2. (289 aa)
Nck1Cytoplasmic protein. (377 aa)
Usp9xProbable ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2317 aa)
Epha2Ephrin type-A receptor 2 isoform X2. (976 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
Stam2Signal transducing adapter molecule 2 isoform X1. (521 aa)
Sptan1Spectrin alpha chain, non-erythrocytic 1. (219 aa)
Myo6Unconventional myosin-VI isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1293 aa)
Peak1Pseudopodium-enriched atypical kinase 1. (1554 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
RhouRho-related GTP-binding protein RhoU. (170 aa)
HgsHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (775 aa)
Dlg5Disks large homolog 5; Belongs to the MAGUK family. (263 aa)
Arhgap31Rho GTPase-activating protein 31. (1434 aa)
Arhgap30Rho GTPase-activating protein 30 isoform X1. (67 aa)
Macf1Microtubule-actin cross-linking factor 1 isoform X5. (544 aa)
ENSDORP00000022680annotation not available (1063 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
Pak2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (507 aa)
Wdr6WD repeat-containing protein 6. (1015 aa)
Arhgef7Rho guanine nucleotide exchange factor 7. (820 aa)
Srgap2SLIT-ROBO Rho GTPase-activating protein 2 isoform X3. (1071 aa)
Vangl1Vang-like protein. (524 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Pard6aPartitioning defective 6 homolog alpha. (345 aa)
Depdc1bDEP domain-containing protein 1B. (476 aa)
Sptbn1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
Pak3Non-specific serine/threonine protein kinase. (559 aa)
Nck2Cytoplasmic protein. (380 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Itsn2Intersectin-2. (1616 aa)
Git1ARF GTPase-activating protein GIT1. (758 aa)
Arhgef6Rho guanine nucleotide exchange factor 6 isoform X1. (302 aa)
DstDystonin isoform X1. (5327 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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