STRINGSTRING
Il21 Il21 Ccl17 Ccl17 Lck Lck Mtor Mtor Runx1 Runx1 Btbd16 Btbd16 Myb Myb Rbpj Rbpj Btla Btla Kirrel Kirrel Slamf1 Slamf1 Il17a Il17a Icos Icos Il10 Il10 Nkap Nkap Zbtb16 Zbtb16 Rela Rela Hdac3 Hdac3 Il18 Il18 Cd44 Cd44 Id2 Id2 Cd5l Cd5l Cd40 Cd40 Src Src Eomes Eomes Fyn Fyn Ccl22 Ccl22 Bach2 Bach2 Bcl11b Bcl11b Gata3 Gata3 Batf Batf Runx3 Runx3 Cd40lg Cd40lg Prkcq Prkcq Tcf12 Tcf12 Cd1d Cd1d Bcr Bcr Cxcl16 Cxcl16 Cyld Cyld Il7 Il7 Egr2 Egr2 Cxcr5 Cxcr5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Il21Interleukin; Belongs to the IL-15/IL-21 family. (156 aa)
Ccl17C-C motif chemokine 17. (102 aa)
LckTyrosine-protein kinase. (509 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
Runx1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (468 aa)
Btbd16BTB/POZ domain-containing protein 16. (405 aa)
MybTranscriptional activator Myb. (761 aa)
RbpjRecombining binding protein suppressor of hairless isoform X1. (526 aa)
BtlaB- and T-lymphocyte attenuator isoform X1. (300 aa)
KirrelKin of IRRE-like protein 1. (592 aa)
Slamf1Signaling lymphocytic activation molecule. (338 aa)
Il17ainterleukin-17A. (156 aa)
IcosInducible T-cell costimulator isoform X1. (202 aa)
Il10Interleukin-10. (178 aa)
NkapNF-kappa-B-activating protein. (264 aa)
Zbtb16Zinc finger and BTB domain-containing protein 16 isoform X1. (673 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
Hdac3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (432 aa)
Il18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (183 aa)
Cd44CD44 antigen isoform X7. (210 aa)
Id2DNA-binding protein inhibitor ID-2. (116 aa)
Cd5lCD5 antigen-like. (355 aa)
Cd40Tumor necrosis factor receptor superfamily member 5 isoform X1. (279 aa)
SrcTyrosine-protein kinase. (539 aa)
EomesEomesodermin homolog isoform X1. (695 aa)
FynTyrosine-protein kinase. (518 aa)
Ccl22C-C motif chemokine 22. (92 aa)
Bach2Transcription regulator protein BACH2. (83 aa)
Bcl11bB-cell lymphoma/leukemia 11B. (868 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
BatfBasic leucine zipper transcriptional factor ATF-like. (124 aa)
Runx3Runt-related transcription factor 3. (337 aa)
Cd40lgCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
PrkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
Tcf12Transcription factor 12 isoform X1. (703 aa)
Cd1dAntigen-presenting glycoprotein CD1d isoform X1. (337 aa)
BcrBreakpoint cluster region protein. (1171 aa)
Cxcl16C-X-C motif chemokine 16. (251 aa)
CyldUbiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family. (957 aa)
Il7Interleukin-7 isoform X1. (156 aa)
Egr2E3 SUMO-protein ligase EGR2. (72 aa)
Cxcr5C-X-C chemokine receptor type 5 isoform X1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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