STRINGSTRING
ENSDORP00000019550 ENSDORP00000019550 Polh Polh Rev3l Rev3l Gstm3 Gstm3 Map3k5 Map3k5 Bad Bad Bcl2 Bcl2 LOC105989276 LOC105989276 LOC105997419 LOC105997419 Mapk3 Mapk3 Bid Bid Cyct Cyct 4921507P07Rik 4921507P07Rik Atp7b Atp7b Mast3 Mast3 Birc5 Birc5 Mgst3 Mgst3 Msh3 Msh3 Akt1 Akt1 Pik3cb Pik3cb Top2b Top2b Gstt1 Gstt1 Mdm2 Mdm2 Ercc1 Ercc1 Gsto1 Gsto1 Gsto2 Gsto2 Abcc2 Abcc2 Mgst2 Mgst2 Apaf1 Apaf1 Pik3ca Pik3ca Birc2 Birc2 LOC105997438 LOC105997438 Xiap Xiap Faslg Faslg Pdpk1 Pdpk1 Pik3cd Pik3cd Msh6 Msh6 Xpa Xpa Atm Atm LOC105997418 LOC105997418 LOC105987814 LOC105987814 Erbb2 Erbb2 Bax Bax Top2a Top2a Pik3r3 Pik3r3 Mapk1 Mapk1 Gm10053 Gm10053 Gstm7 Gstm7 Atp7a Atp7a ENSDORP00000018543 ENSDORP00000018543 LOC105997437 LOC105997437 LOC105987815 LOC105987815 Slc31a1 Slc31a1 Gstt3 Gstt3 Brca1 Brca1 Casp3 Casp3 Pik3r1 Pik3r1 Gstt4 Gstt4 ENSDORP00000021143 ENSDORP00000021143 ENSDORP00000021275 ENSDORP00000021275 Gsta4 Gsta4 LOC106000559 LOC106000559 LOC105997443 LOC105997443 ENSDORP00000023006 ENSDORP00000023006 Mlh1 Mlh1 Trp53 Trp53 Bak1 Bak1 Msh2 Msh2 Mgst1 Mgst1 ENSDORP00000025725 ENSDORP00000025725 LOC105997442 LOC105997442 ENSDORP00000026425 ENSDORP00000026425 Akt2 Akt2 Gstp3 Gstp3 Bcl2l1 Bcl2l1 Akt3 Akt3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSDORP00000019550annotation not available (99 aa)
PolhDNA polymerase eta. (414 aa)
Rev3lDNA polymerase zeta catalytic subunit. (3096 aa)
Gstm3Glutathione S-transferase Mu 3; Belongs to the GST superfamily. (226 aa)
Map3k5Mitogen-activated protein kinase kinase kinase 5. (144 aa)
BadBcl2-associated agonist of cell death isoform X1. (154 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
LOC105989276Glutathione S-transferase P; Belongs to the GST superfamily. (210 aa)
LOC105997419Glutathione S-transferase. (189 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
CyctCytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
4921507P07RikUncharacterized protein C7orf31 homolog. (560 aa)
Atp7bCopper-transporting ATPase 2. (1448 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Birc5Baculoviral IAP repeat-containing protein 5. (142 aa)
Mgst3Microsomal glutathione S-transferase 3. (164 aa)
Msh3DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1046 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Top2bDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1607 aa)
Gstt1Glutathione S-transferase theta-1-like isoform X1; Belongs to the GST superfamily. (240 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2. (446 aa)
Ercc1DNA excision repair protein ERCC-1 isoform X2. (298 aa)
Gsto1Glutathione S-transferase omega-1. (241 aa)
Gsto2Glutathione S-transferase omega-2; Belongs to the GST superfamily. (245 aa)
Abcc2LOW QUALITY PROTEIN: canalicular multispecific organic anion transporter 1. (1479 aa)
Mgst2Microsomal glutathione S-transferase 2. (123 aa)
Apaf1Apoptotic protease-activating factor 1. (1107 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (573 aa)
LOC105997438Glutathione S-transferase. (213 aa)
XiapE3 ubiquitin-protein ligase XIAP isoform X1. (495 aa)
FaslgTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (276 aa)
Pdpk13-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Msh6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1340 aa)
XpaDNA repair protein complementing XP-A cells. (268 aa)
AtmSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa)
LOC105997418Glutathione S-transferase. (196 aa)
LOC105987814Glutathione S-transferase A3-like. (170 aa)
Erbb2Receptor protein-tyrosine kinase. (1255 aa)
BaxApoptosis regulator BAX. (143 aa)
Top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1510 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Gm10053Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa)
Gstm7Glutathione S-transferase Mu 2; Belongs to the GST superfamily. (218 aa)
Atp7aCopper-transporting ATPase 1. (1488 aa)
ENSDORP00000018543annotation not available (129 aa)
LOC105997437Glutathione S-transferase. (218 aa)
LOC105987815Glutathione S-transferase A1; Belongs to the GST superfamily. (221 aa)
Slc31a1High affinity copper uptake protein 1 isoform X2. (188 aa)
Gstt3Glutathione S-transferase theta-1-like; Belongs to the GST superfamily. (240 aa)
Brca1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (79 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Gstt4Glutathione S-transferase theta-4. (216 aa)
ENSDORP00000021143annotation not available (105 aa)
ENSDORP00000021275annotation not available (206 aa)
Gsta4Glutathione S-transferase A4-like. (204 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
LOC105997443Glutathione S-transferase Mu 1-like. (148 aa)
ENSDORP00000023006annotation not available (100 aa)
Mlh1DNA mismatch repair protein Mlh1 isoform X2. (762 aa)
Trp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa)
Bak1Bcl-2 homologous antagonist/killer. (211 aa)
Msh2DNA mismatch repair protein Msh2. (828 aa)
Mgst1Microsomal glutathione S-transferase 1. (47 aa)
ENSDORP00000025725annotation not available (105 aa)
LOC105997442Glutathione S-transferase. (218 aa)
ENSDORP00000026425annotation not available (105 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Gstp3Glutathione S-transferase P-like. (209 aa)
Bcl2l1Bcl-2-like protein 1 isoform X1. (234 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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