STRINGSTRING
ENSDORP00000023223 ENSDORP00000023223 Pik3ca Pik3ca Prkca Prkca Ep300 Ep300 Aldoc Aldoc Serpine1 Serpine1 LOC106001479 LOC106001479 Eno3 Eno3 Pdha1 Pdha1 Slc2a1 Slc2a1 Rps6 Rps6 Eno1 Eno1 Plcg1 Plcg1 Pik3cd Pik3cd Rela Rela Cybb Cybb Aldob Aldob Egfr Egfr Angpt1 Angpt1 Nppa Nppa Egln3 Egln3 Hmox1 Hmox1 Il6r Il6r Epo Epo Erbb2 Erbb2 Rbx1 Rbx1 Hkdc1 Hkdc1 Prkcb Prkcb Plcg2 Plcg2 Eif4e1b Eif4e1b Camk2b Camk2b ENSDORP00000015937 ENSDORP00000015937 Pfkp Pfkp Pik3r3 Pik3r3 Elob Elob Eif4ebp1 Eif4ebp1 Mapk1 Mapk1 Ldhc Ldhc Camk2a Camk2a LOC105998252 LOC105998252 Mknk2 Mknk2 LOC105995863 LOC105995863 Ldhb Ldhb Pik3r1 Pik3r1 Vhl Vhl Timp1 Timp1 LOC105981059 LOC105981059 Eif4e2 Eif4e2 Camk2d Camk2d Rps6kb2 Rps6kb2 Eloc Eloc Ltf Ltf Ifngr2 Ifngr2 LOC106000559 LOC106000559 Flt1 Flt1 LOC105993236 LOC105993236 Crebbp Crebbp Gapdh Gapdh Tbca Tbca Eif4e Eif4e Nos3 Nos3 LOC105987800 LOC105987800 Arsi Arsi Pgk1 Pgk1 ENSDORP00000023736 ENSDORP00000023736 Tek Tek Insr Insr Stat3 Stat3 ENSDORP00000024671 ENSDORP00000024671 Pdk1 Pdk1 LOC105987731 LOC105987731 Edn1 Edn1 Eno2 Eno2 Akt2 Akt2 Pdhb Pdhb Aldoa Aldoa Akt3 Akt3 Hk1 Hk1 ENSDORP00000027934 ENSDORP00000027934 Pfkm Pfkm Igf1 Igf1 Egf Egf Nos2 Nos2 Cul2 Cul2 Cdkn1b Cdkn1b Map2k2 Map2k2 Tlr4 Tlr4 Map2k1 Map2k1 Bcl2 Bcl2 Pfkfb3 Pfkfb3 Aldoa-2 Aldoa-2 Mapk3 Mapk3 LOC105988035 LOC105988035 ENSDORP00000003419 ENSDORP00000003419 Mtor Mtor Ifngr1 Ifngr1 Prkcg Prkcg Mast3 Mast3 Hif1a Hif1a Igf1r Igf1r Angpt2 Angpt2 Camk2g Camk2g Akt1 Akt1 Hk3 Hk3 Pik3cb Pik3cb Hk2 Hk2 Egln1 Egln1 Pfkl Pfkl Mknk1 Mknk1 Eno4 Eno4 Nfkb1 Nfkb1 Angpt4 Angpt4 LOC105994491 LOC105994491
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSDORP00000023223annotation not available (74 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Ep300Histone acetyltransferase p300. (2345 aa)
AldocFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
Serpine1Plasminogen activator inhibitor 1 isoform X2; Belongs to the serpin family. (401 aa)
LOC106001479Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (492 aa)
Eno3Beta-enolase. (311 aa)
Pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
Slc2a1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
Rps640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
Eno1Alpha-enolase. (434 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
CybbCytochrome b-245 heavy chain. (570 aa)
AldobFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
EgfrReceptor protein-tyrosine kinase. (1215 aa)
Angpt1Angiopoietin-1 isoform X1. (498 aa)
NppaNatriuretic peptides A. (153 aa)
Egln3LOW QUALITY PROTEIN: egl nine homolog 3. (209 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (285 aa)
Il6rInterleukin-6 receptor subunit alpha. (445 aa)
EpoErythropoietin. (192 aa)
Erbb2Receptor protein-tyrosine kinase. (1255 aa)
Rbx1E3 ubiquitin-protein ligase RBX1. (117 aa)
Hkdc1Putative hexokinase HKDC1. (896 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
Eif4e1bEukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. (231 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta. (644 aa)
ENSDORP00000015937annotation not available (80 aa)
PfkpATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (793 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
ElobTranscription elongation factor B polypeptide 2. (72 aa)
Eif4ebp1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LdhcL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (329 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (488 aa)
LOC105998252Transcription elongation factor B polypeptide 2 pseudogene. (103 aa)
Mknk2MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (464 aa)
LOC105995863Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like. (109 aa)
LdhbL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
VhlVon Hippel-Lindau disease tumor suppressor. (204 aa)
Timp1Metalloproteinase inhibitor 1. (207 aa)
LOC105981059Pyruvate dehydrogenase E1 component subunit beta, mitochondrial pseudogene. (319 aa)
Eif4e2Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family. (208 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X1; Belongs to the protein kinase superfamily. (533 aa)
Rps6kb2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
ElocTranscription elongation factor B polypeptide 1; Belongs to the SKP1 family. (112 aa)
LtfLactotransferrin. (467 aa)
Ifngr2Interferon gamma receptor 2. (297 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Flt1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1331 aa)
LOC105993236L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
CrebbpCREB-binding protein. (2432 aa)
GapdhGlyceraldehyde-3-phosphate dehydrogenase. (324 aa)
TbcaTubulin-specific chaperone A; Belongs to the TBCA family. (108 aa)
Eif4eEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
Nos3Nitric oxide synthase; Produces nitric oxide (NO). (1201 aa)
LOC105987800Vascular endothelial growth factor A isoform X2; Belongs to the PDGF/VEGF growth factor family. (185 aa)
ArsiArylsulfatase I. (573 aa)
Pgk1Phosphoglycerate kinase. (417 aa)
ENSDORP00000023736annotation not available (111 aa)
TekAngiopoietin-1 receptor isoform X1. (1125 aa)
InsrTyrosine-protein kinase receptor. (1183 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
ENSDORP00000024671annotation not available (72 aa)
Pdk1Protein-serine/threonine kinase. (406 aa)
LOC105987731Uncharacterized protein LOC105987731. (169 aa)
Edn1Endothelin-1-like isoform X1. (202 aa)
Eno2Gamma-enolase. (433 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
AldoaKeratin-associated protein 10-2-like. (136 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Hk1Hexokinase-1. (974 aa)
ENSDORP00000027934annotation not available (118 aa)
PfkmATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
Igf1Insulin-like growth factor I isoform X2. (130 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (664 aa)
Nos2Nitric oxide synthase; Produces nitric oxide (NO). (1149 aa)
Cul2Cullin-2; Belongs to the cullin family. (645 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (106 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Tlr4Toll-like receptor 4 isoform X2; Belongs to the Toll-like receptor family. (842 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
Pfkfb36-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X2. (550 aa)
Aldoa-2Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
LOC105988035L-lactate dehydrogenase A chain-like; Belongs to the LDH/MDH superfamily. (335 aa)
ENSDORP00000003419annotation not available (100 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
Ifngr1Interferon gamma receptor 1. (469 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Hif1aHypoxia-inducible factor 1-alpha. (246 aa)
Igf1rTyrosine-protein kinase receptor. (923 aa)
Angpt2Angiopoietin-2. (495 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma. (515 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Hk3Hexokinase-3. (894 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Hk2Hexokinase-2. (917 aa)
Egln1Egl nine homolog 1. (128 aa)
PfklATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (770 aa)
Mknk1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (422 aa)
Eno4Enolase-like protein ENO4. (617 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
Angpt4Angiopoietin-4. (499 aa)
LOC105994491Serotransferrin-like; Belongs to the transferrin family. (225 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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