STRINGSTRING
Fcer1g Fcer1g Grb2 Grb2 Agtr1 Agtr1 Akt3 Akt3 Gna12 Gna12 Akt2 Akt2 Avpr1a Avpr1a Plpp3 Plpp3 ENSDORP00000026390 ENSDORP00000026390 Sphk2 Sphk2 Grm4 Grm4 Ralgds Ralgds Hras Hras Ptgfr Ptgfr Arf2 Arf2 Pdgfrb Pdgfrb Plcb2 Plcb2 Cyth2 Cyth2 Arf6 Arf6 Dgka Dgka Rala Rala Pip5k1a Pip5k1a Dnm2 Dnm2 ENSDORP00000022835 ENSDORP00000022835 Fcer1a Fcer1a F2r F2r Cxcr2 Cxcr2 Pla2g4a Pla2g4a Nras Nras Plpp2 Plpp2 Cyth4 Cyth4 Pik3r5 Pik3r5 Mras Mras LOC106000559 LOC106000559 Lpar4 Lpar4 Grm7 Grm7 Pdgfb Pdgfb Dnm1 Dnm1 Kras Kras Sos2 Sos2 Plcb1 Plcb1 Pld1 Pld1 ENSDORP00000020304 ENSDORP00000020304 Cyth3 Cyth3 Pik3r1 Pik3r1 Pdgfra Pdgfra Kitl Kitl Cxcr1 Cxcr1 Sphk1 Sphk1 Lpar1 Lpar1 Lpar2 Lpar2 F2 F2 Pip5k1c Pip5k1c Rhoa Rhoa Pld2 Pld2 Lpar5 Lpar5 Arf1 Arf1 ENSDORP00000017709 ENSDORP00000017709 Ptrhd1 Ptrhd1 Rras2 Rras2 Grm6 Grm6 Adcy9 Adcy9 Mapk1 Mapk1 Pip5k1b Pip5k1b Pik3r3 Pik3r3 Gna13 Gna13 Rapgef3 Rapgef3 Plcg2 Plcg2 Gab1 Gab1 Agpat3 Agpat3 Agpat4 Agpat4 Plcb4 Plcb4 Rras Rras Lpar3 Lpar3 Dgkg Dgkg Lpar6 Lpar6 Tsc2 Tsc2 ENSDORP00000012797 ENSDORP00000012797 Gpr55 Gpr55 Avpr1b Avpr1b Dgkd Dgkd LOC105981182 LOC105981182 Egfr Egfr Ralb Ralb Pik3cd Pik3cd ENSDORP00000011621 ENSDORP00000011621 Adcy4 Adcy4 Tsc1 Tsc1 Plcg1 Plcg1 Csde1 Csde1 Kras-2 Kras-2 Agt Agt Adcy2 Adcy2 Shc4 Shc4 Cep152 Cep152 Pik3cg Pik3cg Adcy7 Adcy7 Pdgfc Pdgfc Rheb Rheb Ptk2b Ptk2b Agpat1 Agpat1 Gab2 Gab2 Pik3ca Pik3ca Ms4a2 Ms4a2 Agpat5 Agpat5 Cyth1 Cyth1 Dgkq Dgkq Dgkz Dgkz Ptpn11 Ptpn11 Adcy3 Adcy3 Kit Kit Rufy4 Rufy4 Grm1 Grm1 Dgkk Dgkk Plpp1 Plpp1 Rhebl1 Rhebl1 Adcy8 Adcy8 Pik3cb Pik3cb Grm8 Grm8 Dgki Dgki Akt1 Akt1 Rapgef4 Rapgef4 Shc3 Shc3 Pla2g4f Pla2g4f Pla2g4d Pla2g4d Adcy6 Adcy6 Dgkh Dgkh Pik3r6 Pik3r6 Ptk6 Ptk6 Gnas Gnas Mast3 Mast3 Dgke Dgke Grm3 Grm3 Mtor Mtor Shc1 Shc1 Pdgfa Pdgfa Rhoc Rhoc Mapk3 Mapk3 Avpr2 Avpr2 Dgkb Dgkb Dnm3 Dnm3 Sos1 Sos1 Pla2g4e Pla2g4e Plcb3 Plcb3 Shc2 Shc2 Grm5 Grm5 Map2k1 Map2k1 Agpat2 Agpat2 Map2k2 Map2k2 Grm2 Grm2 Adcy1 Adcy1 Syk Syk Egf Egf Zfp408 Zfp408 Adcy5 Adcy5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fcer1gHigh affinity immunoglobulin epsilon receptor subunit gamma. (69 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Agtr1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Gna12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Avpr1aVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (418 aa)
Plpp3Lipid phosphate phosphohydrolase 3. (312 aa)
ENSDORP00000026390annotation not available (153 aa)
Sphk2Sphingosine kinase 2. (619 aa)
Grm4Metabotropic glutamate receptor 4. (911 aa)
RalgdsRal guanine nucleotide dissociation stimulator isoform X2. (855 aa)
HrasGTPase HRas isoform X1. (192 aa)
PtgfrProstaglandin F2-alpha receptor; Belongs to the G-protein coupled receptor 1 family. (365 aa)
Arf2ADP-ribosylation factor 2; Belongs to the small GTPase superfamily. Arf family. (181 aa)
PdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
Cyth2Cytohesin-2. (399 aa)
Arf6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
DgkaDiacylglycerol kinase. (642 aa)
RalaRas-related protein Ral-A. (206 aa)
Pip5k1aPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha. (569 aa)
Dnm2Dynamin-2 isoform X5; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
ENSDORP00000022835annotation not available (193 aa)
Fcer1aHigh affinity immunoglobulin epsilon receptor subunit alpha isoform X1. (250 aa)
F2rProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (428 aa)
Cxcr2C-X-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (350 aa)
Pla2g4aPhospholipase A2. (750 aa)
NrasGTPase NRas. (189 aa)
Plpp2Lipid phosphate phosphohydrolase 2. (298 aa)
Cyth4Cytohesin-4. (386 aa)
Pik3r5Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (872 aa)
MrasRas-related protein M-Ras. (208 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Lpar4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
Grm7Metabotropic glutamate receptor 7 isoform X1. (918 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
Dnm1Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
Sos2Son of sevenless homolog 2. (1320 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
Pld1Phospholipase. (968 aa)
ENSDORP00000020304annotation not available (160 aa)
Cyth3Cytohesin-3. (405 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
KitlKit ligand. (231 aa)
Cxcr1C-X-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
Sphk1Sphingosine kinase 1. (372 aa)
Lpar1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Lpar2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (349 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (619 aa)
Pip5k1cLOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (976 aa)
RhoaTransforming protein RhoA. (193 aa)
Pld2Phospholipase. (934 aa)
Lpar5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (373 aa)
Arf1ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
ENSDORP00000017709annotation not available (94 aa)
Ptrhd1Putative peptidyl-tRNA hydrolase PTRHD1. (146 aa)
Rras2Ras-related protein R-Ras2 isoform X1. (171 aa)
Grm6LOW QUALITY PROTEIN: metabotropic glutamate receptor 6. (545 aa)
Adcy9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1330 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Pip5k1bPhosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X3. (540 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Gna13Guanine nucleotide-binding protein subunit alpha-13. (372 aa)
Rapgef3Rap guanine nucleotide exchange factor 3. (216 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
Gab1GRB2-associated-binding protein 1. (707 aa)
Agpat31-acyl-sn-glycerol-3-phosphate acyltransferase gamma. (53 aa)
Agpat41-acyl-sn-glycerol-3-phosphate acyltransferase delta. (378 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa)
RrasRas-related protein R-Ras. (218 aa)
Lpar3Lysophosphatidic acid receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
DgkgDiacylglycerol kinase. (756 aa)
Lpar6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (344 aa)
Tsc2Tuberin isoform X1. (1809 aa)
ENSDORP00000012797annotation not available (192 aa)
Gpr55G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (318 aa)
Avpr1bVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
DgkdDiacylglycerol kinase. (1133 aa)
LOC105981182Phospholipase A2. (787 aa)
EgfrReceptor protein-tyrosine kinase. (1215 aa)
RalbRas-related protein Ral-B. (206 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
ENSDORP00000011621annotation not available (186 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
Tsc1Hamartin isoform X1. (1121 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
AgtAngiotensinogen; Belongs to the serpin family. (473 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (854 aa)
Shc4SHC-transforming protein 4. (340 aa)
Cep152Centrosomal protein of 152 kDa. (655 aa)
Pik3cgPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (264 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
PdgfcPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (344 aa)
RhebGTP-binding protein Rheb. (112 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
Agpat11-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (287 aa)
Gab2GRB2-associated-binding protein 2. (608 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Ms4a2High affinity immunoglobulin epsilon receptor subunit beta. (243 aa)
Agpat51-acyl-sn-glycerol-3-phosphate acyltransferase epsilon. (277 aa)
Cyth1Cytohesin-1. (396 aa)
DgkqDiacylglycerol kinase. (898 aa)
DgkzDiacylglycerol kinase. (707 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
KitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
Rufy4RUN and FYVE domain-containing protein 4. (525 aa)
Grm1LOW QUALITY PROTEIN: metabotropic glutamate receptor 1. (906 aa)
DgkkDiacylglycerol kinase. (1273 aa)
Plpp1Lipid phosphate phosphohydrolase 1 isoform X2. (285 aa)
Rhebl1GTPase RhebL1. (176 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Grm8Metabotropic glutamate receptor 8 isoform X1. (908 aa)
DgkiDiacylglycerol kinase. (901 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Rapgef4Rap guanine nucleotide exchange factor 4 isoform X1. (838 aa)
Shc3SHC-transforming protein 3. (598 aa)
Pla2g4fPhospholipase A2, group IVF. (843 aa)
Pla2g4dPhospholipase A2. (708 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
DgkhDiacylglycerol kinase. (1145 aa)
Pik3r6LOW QUALITY PROTEIN: phosphoinositide 3-kinase regulatory subunit 6. (682 aa)
Ptk6Tyrosine-protein kinase. (451 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
DgkeDiacylglycerol kinase. (527 aa)
Grm3Metabotropic glutamate receptor 3. (882 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
PdgfaPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (210 aa)
RhocRho-related GTP-binding protein RhoC. (193 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Avpr2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
DgkbDiacylglycerol kinase. (795 aa)
Dnm3Dynamin-3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (845 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Pla2g4ePhospholipase A2. (866 aa)
Plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
Shc2SHC-transforming protein 2. (513 aa)
Grm5Metabotropic glutamate receptor 5. (1096 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Agpat21-acyl-sn-glycerol-3-phosphate acyltransferase beta. (191 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Grm2Metabotropic glutamate receptor 2. (872 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (937 aa)
SykTyrosine-protein kinase. (633 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (664 aa)
Zfp408Zinc finger protein 408. (667 aa)
Adcy5Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1186 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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