STRINGSTRING
Capn11 Capn11 Gm10053 Gm10053 Mapk1 Mapk1 ENSDORP00000016827 ENSDORP00000016827 Dffa Dffa Rem1 Rem1 Pik3r3 Pik3r3 Dffb Dffb Bcl2l11 Bcl2l11 Pidd1 Pidd1 Traf1 Traf1 Map3k14 Map3k14 Htra1 Htra1 Bax Bax Tradd Tradd Casp7 Casp7 Ctsc Ctsc Capn2 Capn2 Daxx Daxx Ifitm10 Ifitm10 Atm Atm Htra2 Htra2 Rrad Rrad Ikbkg Ikbkg Tnfsf10 Tnfsf10 LOC105997195 LOC105997195 Akt3 Akt3 Bcl2l1 Bcl2l1 Actl11 Actl11 LOC105983251 LOC105983251 Ctsz Ctsz Akt2 Akt2 ENSDORP00000026737 ENSDORP00000026737 Suco Suco Fos Fos ENSDORP00000026425 ENSDORP00000026425 ENSDORP00000026241 ENSDORP00000026241 Bcl2a1 Bcl2a1 ENSDORP00000025725 ENSDORP00000025725 Mapk8 Mapk8 Hras Hras Parp4 Parp4 Tuba4a Tuba4a Capn1 Capn1 Itpr1 Itpr1 Lmnb2 Lmnb2 Bak1 Bak1 LOC105989056 LOC105989056 Trp53 Trp53 Septin4 Septin4 Eif2ak3 Eif2ak3 ENSDORP00000023006 ENSDORP00000023006 Dab2ip Dab2ip Itpr2 Itpr2 Nras Nras Actb Actb Ngf Ngf LOC106000559 LOC106000559 Tuba1c Tuba1c Capn8 Capn8 ENSDORP00000021143 ENSDORP00000021143 Kras Kras LOC106002269 LOC106002269 Pik3r1 Pik3r1 Casp3 Casp3 Tuba8 Tuba8 Spta1 Spta1 ENSDORP00000019550 ENSDORP00000019550 Gadd45b Gadd45b Ern2 Ern2 Ctsk Ctsk Sptan1 Sptan1 LOC105981516 LOC105981516 LOC105981880 LOC105981880 Map2k2 Map2k2 Map2k1 Map2k1 Itpr3 Itpr3 Ern1 Ern1 Htra4 Htra4 Map3k5 Map3k5 Ppp1r14bl Ppp1r14bl Bad Bad Bcl2 Bcl2 Ctso Ctso Parp2 Parp2 Cenpu Cenpu Casp2 Casp2 Mapk3 Mapk3 Aifm1 Aifm1 Capn9 Capn9 Actrt2 Actrt2 Gem Gem Mapk9 Mapk9 Bid Bid Cyct Cyct 4921507P07Rik 4921507P07Rik LOC105999168 LOC105999168 Traf2 Traf2 Mast3 Mast3 Birc5 Birc5 Atf4 Atf4 Endog Endog Ntrk1 Ntrk1 Parp1 Parp1 Akt1 Akt1 Pik3cb Pik3cb Lmnb1 Lmnb1 Tuba1a Tuba1a Capn12 Capn12 Ddit3 Ddit3 Nfkb1 Nfkb1 Capn3 Capn3 Actl7b Actl7b Actl7a Actl7a Ctsf Ctsf Apaf1 Apaf1 Pik3ca Pik3ca Prf1 Prf1 Ptpn13 Ptpn13 Ctsw Ctsw Mapk10 Mapk10 Ctsh Ctsh Birc2 Birc2 Ripk1 Ripk1 Xiap Xiap Ctss Ctss Mcl1 Mcl1 Kras-2 Kras-2 Csde1 Csde1 Gadd45a Gadd45a Faslg Faslg Pdpk1 Pdpk1 Chuk Chuk Gadd45g Gadd45g Pik3cd Pik3cd Tnf Tnf Ctsb Ctsb Tubal3 Tubal3 Rela Rela Diablo Diablo Ikbkb Ikbkb Nfkbia Nfkbia Casp6 Casp6 LOC105998610 LOC105998610 Lmna Lmna Exog Exog Aifm1-2 Aifm1-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Capn11Calpain-11; Belongs to the peptidase C2 family. (706 aa)
Gm10053Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ENSDORP00000016827annotation not available (299 aa)
DffaDNAation factor subunit alpha isoform X1. (331 aa)
Rem1GTP-binding protein REM 1. (252 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
DffbDNAation factor subunit beta. (301 aa)
Bcl2l11Bcl-2-like protein 11 isoform X1. (200 aa)
Pidd1P53-induced death domain-containing protein 1 isoform X1. (885 aa)
Traf1TNF receptor-associated factor. (408 aa)
Map3k14Mitogen-activated protein kinase kinase kinase 14 isoform X1. (933 aa)
Htra1Serine protease HTRA1. (413 aa)
BaxApoptosis regulator BAX. (143 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein. (309 aa)
Casp7Caspase-7; Belongs to the peptidase C14A family. (305 aa)
CtscDipeptidyl peptidase 1 isoform X1; Belongs to the peptidase C1 family. (462 aa)
Capn2Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (700 aa)
DaxxDeath domain-associated protein 6 isoform X1. (745 aa)
Ifitm10Interferon-induced transmembrane protein 10. (198 aa)
AtmSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa)
Htra2Serine protease HTRA2, mitochondrial. (458 aa)
RradGTP-binding protein RAD. (296 aa)
IkbkgNF-kappa-B essential modulator isoform X3. (410 aa)
Tnfsf10Tumor necrosis factor ligand superfamily member. (288 aa)
LOC105997195Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Bcl2l1Bcl-2-like protein 1 isoform X1. (234 aa)
Actl11Uncharacterized protein LOC105994564; Belongs to the actin family. (1215 aa)
LOC105983251Uncharacterized protein C17orf47 homolog. (494 aa)
CtszCathepsin Z; Belongs to the peptidase C1 family. (290 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSDORP00000026737annotation not available (449 aa)
SucoSUN domain-containing ossification factor. (1216 aa)
FosProto-oncogene c-Fos. (380 aa)
ENSDORP00000026425annotation not available (105 aa)
ENSDORP00000026241annotation not available (302 aa)
Bcl2a1Bcl-2-related protein A1. (139 aa)
ENSDORP00000025725annotation not available (105 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
HrasGTPase HRas isoform X1. (192 aa)
Parp4Poly [ADP-ribose] polymerase. (1374 aa)
Tuba4aTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
Capn1Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (714 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2702 aa)
Lmnb2lamin-B2; Belongs to the intermediate filament family. (597 aa)
Bak1Bcl-2 homologous antagonist/killer. (211 aa)
LOC105989056Tumor necrosis factor receptor superfamily member 23-like. (120 aa)
Trp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa)
Septin4Septin-4 isoform X2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (372 aa)
Eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1025 aa)
ENSDORP00000023006annotation not available (100 aa)
Dab2ipDisabled homolog 2-interacting protein isoform X1. (1166 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2678 aa)
NrasGTPase NRas. (189 aa)
ActbActin, cytoplasmic 1. (375 aa)
NgfBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Tuba1cTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
Capn8Calpain-8; Belongs to the peptidase C2 family. (713 aa)
ENSDORP00000021143annotation not available (105 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
LOC106002269Tubulin alpha-1B chain-like. (302 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
Tuba8LOW QUALITY PROTEIN: tubulin alpha-8 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (298 aa)
Spta1Spectrin alpha chain, erythrocytic 1. (1959 aa)
ENSDORP00000019550annotation not available (99 aa)
Gadd45bGrowth arrest and DNA damage-inducible protein GADD45 beta. (160 aa)
Ern2Serine/threonine-protein kinase/endoribonuclease IRE2. (981 aa)
CtskCathepsin K; Belongs to the peptidase C1 family. (329 aa)
Sptan1Spectrin alpha chain, non-erythrocytic 1. (219 aa)
LOC105981516Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
LOC105981880LOW QUALITY PROTEIN: tubulin alpha chain-like. (441 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3 isoform X3. (2668 aa)
Ern1Serine/threonine-protein kinase/endoribonuclease IRE1. (406 aa)
Htra4Serine protease HTRA4. (483 aa)
Map3k5Mitogen-activated protein kinase kinase kinase 5. (144 aa)
Ppp1r14blProtein phosphatase 1 regulatory subunit 14B. (141 aa)
BadBcl2-associated agonist of cell death isoform X1. (154 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
CtsoCathepsin O; Belongs to the peptidase C1 family. (275 aa)
Parp2Poly [ADP-ribose] polymerase. (546 aa)
CenpuCentromere protein U. (281 aa)
Casp2Caspase-2; Belongs to the peptidase C14A family. (286 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Aifm1Apoptosis inducing factor mitochondria associated 1. (274 aa)
Capn9Calpain-9 isoform X1; Belongs to the peptidase C2 family. (701 aa)
Actrt2Actin-related protein T2; Belongs to the actin family. (377 aa)
GemGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
Mapk9Mitogen-activated protein kinase. (382 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
CyctCytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
4921507P07RikUncharacterized protein C7orf31 homolog. (560 aa)
LOC105999168Hermansky-Pudlak syndrome 5 protein-like. (840 aa)
Traf2TNF receptor-associated factor. (484 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Birc5Baculoviral IAP repeat-containing protein 5. (142 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (345 aa)
EndogEndonuclease. (277 aa)
Ntrk1Tyrosine-protein kinase receptor. (799 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1000 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Lmnb1lamin-B1; Belongs to the intermediate filament family. (372 aa)
Tuba1aTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
Capn12Calpain-12; Belongs to the peptidase C2 family. (676 aa)
Ddit3DNA damage-inducible transcript 3 protein. (166 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
Capn3Calpain-3 isoform X2; Belongs to the peptidase C2 family. (815 aa)
Actl7bActin-like protein 7B; Belongs to the actin family. (418 aa)
Actl7aActin-like protein 7A; Belongs to the actin family. (439 aa)
CtsfCathepsin F; Belongs to the peptidase C1 family. (457 aa)
Apaf1Apoptotic protease-activating factor 1. (1107 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Prf1Perforin-1. (554 aa)
Ptpn13Tyrosine-protein phosphatase non-receptor type 13. (2409 aa)
CtswCathepsin W; Belongs to the peptidase C1 family. (359 aa)
Mapk10Mitogen-activated protein kinase. (486 aa)
CtshPro-cathepsin H; Belongs to the peptidase C1 family. (310 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (573 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (662 aa)
XiapE3 ubiquitin-protein ligase XIAP isoform X1. (495 aa)
CtssLOW QUALITY PROTEIN: cathepsin S; Belongs to the peptidase C1 family. (305 aa)
Mcl1Induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1. (349 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Gadd45aGrowth arrest and DNA damage-inducible protein GADD45 alpha. (166 aa)
FaslgTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (276 aa)
Pdpk13-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
Gadd45gGrowth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
TnfTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (220 aa)
CtsbCathepsin B; Belongs to the peptidase C1 family. (339 aa)
Tubal3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (435 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
DiabloDiablo homolog, mitochondrial. (235 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta. (732 aa)
NfkbiaNF-kappa-B inhibitor alpha. (224 aa)
Casp6Caspase-6 isoform X2; Belongs to the peptidase C14A family. (274 aa)
LOC105998610Interferon-induced transmembrane protein 1-like. (118 aa)
LmnaLamin; Belongs to the intermediate filament family. (663 aa)
ExogNuclease EXOG, mitochondrial. (369 aa)
Aifm1-2Apoptosis-inducing factor 1, mitochondrial. (327 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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