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Nfatc4 Nfatc4 Pak7 Pak7 Efna1 Efna1 Sema6a Sema6a Ppp3ca Ppp3ca Srgap2 Srgap2 Plxnc1 Plxnc1 Ppp3cb Ppp3cb Unc5a Unc5a Sema3f Sema3f Efnb1 Efnb1 Sema6c Sema6c Hras Hras Ldah Ldah Efna2 Efna2 Ntng2 Ntng2 Ablim2 Ablim2 Gm49909 Gm49909 Pak2 Pak2 LOC105994487 LOC105994487 Sema4a Sema4a Efnb3 Efnb3 Fzd3 Fzd3 Pdk1 Pdk1 Slit2 Slit2 Ephb1 Ephb1 Adam15 Adam15 Pard6g Pard6g Pak6 Pak6 Slit3 Slit3 Pak4-2 Pak4-2 Gsk3b Gsk3b ENSDORP00000023306 ENSDORP00000023306 Plxnb3 Plxnb3 Rgma Rgma LOC105989352 LOC105989352 Plxna1 Plxna1 ENSDORP00000022835 ENSDORP00000022835 Enah Enah Ppp3cc Ppp3cc Nras Nras Efna4 Efna4 Wnt5a Wnt5a Lrrc4 Lrrc4 Epha10 Epha10 LOC106000559 LOC106000559 Kras Kras Camk2d Camk2d Sema5a Sema5a Pik3r1 Pik3r1 LOC105993816 LOC105993816 Slit1 Slit1 Met Met Ptk2 Ptk2 Nfatc3 Nfatc3 Nfatc2 Nfatc2 Cxcl12 Cxcl12 Lrrc4c Lrrc4c Rnd1 Rnd1 Ssh3 Ssh3 Ppp3r1 Ppp3r1 Rhoa Rhoa Rgs3-2 Rgs3-2 Camk2a Camk2a ENSDORP00000017594 ENSDORP00000017594 Efna5 Efna5 Gnai1 Gnai1 Mapk1 Mapk1 Pak1 Pak1 Sema3e Sema3e Epha2 Epha2 Cxcr4 Cxcr4 Dpysl2 Dpysl2 Pik3r3 Pik3r3 Arhgef12 Arhgef12 Ssh2 Ssh2 Plxna4 Plxna4 Camk2b Camk2b Wnt4 Wnt4 Sema4c Sema4c Plcg2 Plcg2 Limk2 Limk2 Ntn1 Ntn1 Trpc3 Trpc3 Ablim1 Ablim1 Sema3a Sema3a Rras Rras Gnai3 Gnai3 Epha8 Epha8 Rac1 Rac1 Sema4f Sema4f Nck1 Nck1 L1cam L1cam Ryk Ryk Dpysl5 Dpysl5 Fes Fes Trpc1 Trpc1 Epha7 Epha7 Sema5b Sema5b Plxnb2 Plxnb2 Neo1 Neo1 Rgs3 Rgs3 Pik3cd Pik3cd ENSDORP00000011621 ENSDORP00000011621 Trpc5 Trpc5 Epha5 Epha5 Robo1 Robo1 Plcg1 Plcg1 Ephb2 Ephb2 Csde1 Csde1 Ntn4 Ntn4 Kras-2 Kras-2 Efnb2 Efnb2 Trpc7 Trpc7 Ccdc125 Ccdc125 Robo3 Robo3 Unc5d Unc5d Rock1 Rock1 Cfl1 Cfl1 Sema4d Sema4d Pik3ca Pik3ca Epha6 Epha6 Trpc4 Trpc4 Arsi Arsi Bmpr2 Bmpr2 Rac2 Rac2 Ephb6 Ephb6 Ptpn11 Ptpn11 Rock2 Rock2 Ephb4 Ephb4 Sema3b Sema3b Itgb1 Itgb1 Sema3c Sema3c Pard6b Pard6b Efna3 Efna3 Srgap1 Srgap1 Pak4 Pak4 Plxna2 Plxna2 Cdk5 Cdk5 Gnai2 Gnai2 Pik3cb Pik3cb Sema4b Sema4b Ntng1 Ntng1 Cfl2 Cfl2 Camk2g Camk2g Trpc6 Trpc6 Smo Smo Epha4 Epha4 Ablim3 Ablim3 Ptk6 Ptk6 Sema4g Sema4g Mast3 Mast3 Epha3 Epha3 Sema3g Sema3g Nck2 Nck2 Rhoc Rhoc Mapk3 Mapk3 Ephb3 Ephb3 Plxnb1 Plxnb1 Nrp1 Nrp1 Robo2 Robo2 Unc5b Unc5b Epha1 Epha1 Pak3 Pak3 Rhod Rhod Dcc Dcc Rasa1 Rasa1 Ptch1 Ptch1 Sema6b Sema6b Myl9 Myl9 Srgap3 Srgap3 Sema6d Sema6d Ssh1 Ssh1 Plxna3 Plxna3 Sema3d Sema3d Sema7a Sema7a Ilk Ilk Pard3 Pard3 Boc Boc Unc5c Unc5c Bmpr1b Bmpr1b Limk1 Limk1 Pard6a Pard6a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Nfatc4Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (899 aa)
Pak7Non-specific serine/threonine protein kinase. (338 aa)
Efna1ephrin-A1; Belongs to the ephrin family. (203 aa)
Sema6asemaphorin-6A; Belongs to the semaphorin family. (601 aa)
Ppp3caSerine/threonine-protein phosphatase. (479 aa)
Srgap2SLIT-ROBO Rho GTPase-activating protein 2 isoform X3. (1071 aa)
Plxnc1plexin-C1. (412 aa)
Ppp3cbSerine/threonine-protein phosphatase. (492 aa)
Unc5aNetrin receptor UNC5A. (893 aa)
Sema3fsemaphorin-3F isoform X1; Belongs to the semaphorin family. (785 aa)
Efnb1ephrin-B1; Belongs to the ephrin family. (345 aa)
Sema6csemaphorin-6C; Belongs to the semaphorin family. (802 aa)
HrasGTPase HRas isoform X1. (192 aa)
LdahUPF0554 protein C2orf43 homolog isoform X1. (325 aa)
Efna2ephrin-A2; Belongs to the ephrin family. (197 aa)
Ntng2netrin-G2. (529 aa)
Ablim2Actin-binding LIM protein 2. (651 aa)
Gm49909Myosin regulatory light chain 12B. (172 aa)
Pak2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (507 aa)
LOC105994487Ephrin type-B receptor 1-like. (304 aa)
Sema4asemaphorin-4A; Belongs to the semaphorin family. (760 aa)
Efnb3ephrin-B3; Belongs to the ephrin family. (340 aa)
Fzd3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
Pdk1Protein-serine/threonine kinase. (406 aa)
Slit2Slit homolog 2 protein. (1344 aa)
Ephb1Ephrin type-B receptor 1. (836 aa)
Adam15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (864 aa)
Pard6gPartitioning defective 6 homolog gamma. (361 aa)
Pak6Non-specific serine/threonine protein kinase. (668 aa)
Slit3Slit homolog 3 protein. (1257 aa)
Pak4-2Non-specific serine/threonine protein kinase. (110 aa)
Gsk3bGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
ENSDORP00000023306annotation not available (141 aa)
Plxnb3plexin-B3. (1888 aa)
RgmaRepulsive guidance molecule A. (452 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
Plxna1plexin-A1. (1893 aa)
ENSDORP00000022835annotation not available (193 aa)
EnahENAH actin regulator. (731 aa)
Ppp3ccSerine/threonine-protein phosphatase. (478 aa)
NrasGTPase NRas. (189 aa)
Efna4ephrin-A4; Belongs to the ephrin family. (204 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
Lrrc4Leucine-rich repeat-containing protein 4. (652 aa)
Epha10Ephrin type-A receptor 10. (944 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X1; Belongs to the protein kinase superfamily. (533 aa)
Sema5asemaphorin-5A. (1074 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC105993816Myosin regulatory light polypeptide 9. (172 aa)
Slit1Slit homolog 1 protein isoform X1. (1535 aa)
MetHepatocyte growth factor receptor. (1382 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
Nfatc3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1077 aa)
Nfatc2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (728 aa)
Cxcl12Stromal cell-derived factor 1 isoform X2; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
Lrrc4cLeucine-rich repeat-containing protein 4C. (640 aa)
Rnd1Rho-related GTP-binding protein Rho6. (232 aa)
Ssh3Protein phosphatase Slingshot homolog 3. (645 aa)
Ppp3r1Calcineurin subunit B type 1. (169 aa)
RhoaTransforming protein RhoA. (193 aa)
Rgs3-2Regulator of G-protein signaling 3 isoform X3. (192 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (488 aa)
ENSDORP00000017594annotation not available (251 aa)
Efna5ephrin-A5 isoform X1; Belongs to the ephrin family. (188 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
Sema3esemaphorin-3E; Belongs to the semaphorin family. (775 aa)
Epha2Ephrin type-A receptor 2 isoform X2. (976 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (357 aa)
Dpysl2Dihydropyrimidinase-related protein 2 isoform X2. (572 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Arhgef12Rho guanine nucleotide exchange factor 12. (1511 aa)
Ssh2Protein phosphatase Slingshot homolog 2. (216 aa)
Plxna4plexin-A4 isoform X1. (1893 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta. (644 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
Sema4csemaphorin-4C; Belongs to the semaphorin family. (831 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
Limk2LIM domain kinase 2 isoform X2. (617 aa)
Ntn1Netrin-1. (581 aa)
Trpc3Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (836 aa)
Ablim1Actin-binding LIM protein 1 isoform X1. (700 aa)
Sema3asemaphorin-3A; Belongs to the semaphorin family. (772 aa)
RrasRas-related protein R-Ras. (218 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
Epha8Ephrin type-A receptor 8. (981 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
Sema4fsemaphorin-4F isoform X1; Belongs to the semaphorin family. (768 aa)
Nck1Cytoplasmic protein. (377 aa)
L1camNeural cell adhesion molecule L1 isoform X1. (1260 aa)
RykTyrosine-protein kinase RYK isoform X1. (475 aa)
Dpysl5Dihydropyrimidinase-related protein 5. (564 aa)
FesFES proto-oncogene, tyrosine kinase. (95 aa)
Trpc1Short transient receptor potential channel 1. (756 aa)
Epha7Ephrin type-A receptor 7 isoform X1. (998 aa)
Sema5bsemaphorin-5B isoform X1. (1120 aa)
Plxnb2Plexin B2. (470 aa)
Neo1Neogenin. (1436 aa)
Rgs3Regulator of G-protein signaling 3 isoform X2. (610 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
ENSDORP00000011621annotation not available (186 aa)
Trpc5Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (966 aa)
Epha5Ephrin type-A receptor 5 isoform X1. (1038 aa)
Robo1Roundabout homolog 1 isoform X2. (1611 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Ephb2Ephrin type-B receptor 2 isoform X2. (1018 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Ntn4Netrin-4. (618 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Efnb2ephrin-B2; Belongs to the ephrin family. (325 aa)
Trpc7Short transient receptor potential channel 7 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
Ccdc125Coiled-coil domain-containing protein 125. (484 aa)
Robo3Roundabout homolog 3. (1393 aa)
Unc5dNetrin receptor UNC5D isoform X1. (957 aa)
Rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
Cfl1Cofilin-1; Belongs to the actin-binding proteins ADF family. (168 aa)
Sema4dsemaphorin-4D; Belongs to the semaphorin family. (862 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Epha6Receptor protein-tyrosine kinase. (288 aa)
Trpc4Short transient receptor potential channel 4 isoform X2; Belongs to the transient receptor (TC 1.A.4) family. (978 aa)
ArsiArylsulfatase I. (573 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (933 aa)
Rac2Ras-related C3 botulinum toxin substrate 2. (184 aa)
Ephb6Ephrin type-B receptor 6. (1015 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Rock2Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1114 aa)
Ephb4Ephrin type-B receptor 4. (934 aa)
Sema3bsemaphorin-3B; Belongs to the semaphorin family. (721 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Sema3csemaphorin-3C; Belongs to the semaphorin family. (752 aa)
Pard6bPartitioning defective 6 homolog beta. (352 aa)
Efna3ephrin-A3 isoform X1; Belongs to the ephrin family. (230 aa)
Srgap1SLIT-ROBO Rho GTPase-activating protein 1 isoform X1. (1065 aa)
Pak4Non-specific serine/threonine protein kinase. (587 aa)
Plxna2plexin-A2. (1891 aa)
Cdk5Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Sema4bsemaphorin-4B; Belongs to the semaphorin family. (808 aa)
Ntng1netrin-G1 isoform X1. (543 aa)
Cfl2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma. (515 aa)
Trpc6Short transient receptor potential channel 6. (513 aa)
SmoSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
Epha4Ephrin type-A receptor 4 isoform X1. (986 aa)
Ablim3Actin-binding LIM protein 3 isoform X2. (683 aa)
Ptk6Tyrosine-protein kinase. (451 aa)
Sema4gsemaphorin-4G; Belongs to the semaphorin family. (838 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Epha3Ephrin type-A receptor 3 isoform X1. (984 aa)
Sema3gsemaphorin-3G; Belongs to the semaphorin family. (774 aa)
Nck2Cytoplasmic protein. (380 aa)
RhocRho-related GTP-binding protein RhoC. (193 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Ephb3Ephrin type-B receptor 3. (998 aa)
Plxnb1plexin-B1. (2130 aa)
Nrp1Neuropilin; Belongs to the neuropilin family. (735 aa)
Robo2Roundabout homolog 2 isoform X4. (1377 aa)
Unc5bNetrin receptor UNC5B isoform X1. (945 aa)
Epha1Ephrin type-A receptor 1 isoform X1. (973 aa)
Pak3Non-specific serine/threonine protein kinase. (559 aa)
RhodRho-related GTP-binding protein RhoD. (181 aa)
DccNetrin receptor DCC. (1447 aa)
Rasa1Ras GTPase-activating protein 1. (813 aa)
Ptch1Protein patched homolog 1. (1300 aa)
Sema6bsemaphorin-6B; Belongs to the semaphorin family. (644 aa)
Myl9Myosin regulatory light polypeptide 9. (172 aa)
Srgap3SLIT-ROBO Rho GTPase-activating protein 3. (346 aa)
Sema6dsemaphorin-6D; Belongs to the semaphorin family. (1073 aa)
Ssh1Protein phosphatase Slingshot homolog 1. (1010 aa)
Plxna3plexin-A3. (1849 aa)
Sema3dsemaphorin-3D isoform X1; Belongs to the semaphorin family. (772 aa)
Sema7asemaphorin-7A; Belongs to the semaphorin family. (643 aa)
IlkIntegrin-linked protein kinase isoform X1. (452 aa)
Pard3Partitioning defective 3 homolog isoform X1. (1294 aa)
BocBrother of CDO isoform X2. (1092 aa)
Unc5cNetrin receptor UNC5C isoform X1. (950 aa)
Bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
Limk1LIM domain kinase 1. (635 aa)
Pard6aPartitioning defective 6 homolog alpha. (345 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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