STRINGSTRING
Ppp2r2c Ppp2r2c Wtip Wtip Fzd3 Fzd3 ENSDORP00000024608 ENSDORP00000024608 Myo15 Myo15 Wnt6 Wnt6 Nf2 Nf2 Fzd6 Fzd6 Wnt9a Wnt9a Dvl2 Dvl2 Tcf7 Tcf7 Bmp6 Bmp6 Dvl3 Dvl3 Birc5 Birc5 Patj Patj Tgfb2 Tgfb2 Areg Areg Actrt2 Actrt2 LOC106002055 LOC106002055 Tgfb1 Tgfb1 Afp Afp Crb2 Crb2 Amot Amot Cdh1 Cdh1 Wnt8b Wnt8b Pard3 Pard3 Bmpr1b Bmpr1b Pard6a Pard6a Sav1 Sav1 Btrc Btrc Dlg3 Dlg3 Ppp1cb Ppp1cb Trp53bp2 Trp53bp2 Tcf7l1 Tcf7l1 Tead1 Tead1 Tgfb3 Tgfb3 Ppp2r2d Ppp2r2d Ppp1ca Ppp1ca Nkd2 Nkd2 Tcf7l2 Tcf7l2 Lats2 Lats2 Ywhaz Ywhaz Csnk1d Csnk1d Limd1 Limd1 Tead3 Tead3 Serpine1 Serpine1 Bmp2 Bmp2 Bmp4 Bmp4 Ppp1cc Ppp1cc Dlg2 Dlg2 Wnt10b Wnt10b Birc2 Birc2 Lrrc1 Lrrc1 Tead2 Tead2 Ctnna1 Ctnna1 Csnk1e Csnk1e Frmd6 Frmd6 Fbxw11 Fbxw11 Bmpr1a Bmpr1a Ctnna3 Ctnna3 Bmpr2 Bmpr2 Smad4 Smad4 Mob1b Mob1b Ppp2r1b Ppp2r1b Id1 Id1 Actl7a Actl7a Actl7b Actl7b Nkd1 Nkd1 Gli2 Gli2 Smad1 Smad1 Ppp2cb Ppp2cb Rassf1 Rassf1 Wnt1 Wnt1 Lef1 Lef1 Sox2 Sox2 Wnt8a Wnt8a Lats1 Lats1 Pard6b Pard6b Wnt9b Wnt9b Fzd1 Fzd1 Wnt11 Wnt11 Wnt10a Wnt10a Pard6g Pard6g Wnt7b Wnt7b Ccnd3 Ccnd3 Gsk3b Gsk3b Smad3 Smad3 ENSDORP00000023068 ENSDORP00000023068 Prkci Prkci Fzd4 Fzd4 Mob1a Mob1a Dlg4 Dlg4 Ywhag Ywhag Wnt5a Wnt5a Yap1 Yap1 Actb Actb Dlg5 Dlg5 Wwc1 Wwc1 Myo15b Myo15b Axin2 Axin2 Ccnd2 Ccnd2 Llgl2 Llgl2 Bmp5 Bmp5 Fzd2 Fzd2 Tead4 Tead4 LOC105997103 LOC105997103 Ppp2ca Ppp2ca ENSDORP00000020585 ENSDORP00000020585 Stk3 Stk3 Axin1 Axin1 Sox3 Sox3 LOC106002162 LOC106002162 Ywhae Ywhae Wnt7a Wnt7a Fzd9 Fzd9 Ccn2 Ccn2 Ywhaq Ywhaq Ajuba Ajuba Snai2 Snai2 Wnt2b Wnt2b Tgfbr1 Tgfbr1 Fzd8 Fzd8 Fgf1 Fgf1 Scrib Scrib Smad2 Smad2 Apc2 Apc2 Ywhah Ywhah Wnt3 Wnt3 Fzd5 Fzd5 Ppp2r2b Ppp2r2b Apc Apc Ccnd1 Ccnd1 Ppp2r2a Ppp2r2a Wnt4 Wnt4 Wnt2 Wnt2 LOC105986097 LOC105986097 Ctnna2 Ctnna2 Gdf5 Gdf5 Prkcz Prkcz Gdf6 Gdf6 Tgfbr2 Tgfbr2 Tp73 Tp73 Id2 Id2 Rassf6 Rassf6 Mpp5 Mpp5 Wnt16 Wnt16 Ppp2r1a Ppp2r1a Dlg1 Dlg1 Amh Amh Fzd7 Fzd7 LOC105996819 LOC105996819 Actl11 Actl11 Llgl1 Llgl1 LOC106002396 LOC106002396 Ywhab Ywhab Smad7 Smad7 Myc Myc Ldah Ldah
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ppp2r2cSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (474 aa)
WtipWilms tumor protein 1-interacting protein. (207 aa)
Fzd3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ENSDORP00000024608annotation not available (540 aa)
Myo15Unconventional myosin-XV isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3534 aa)
Wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
Nf2Merlin isoform X1. (596 aa)
Fzd6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
Wnt9aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
Dvl2Segment polarity protein dishevelled homolog DVL-2 isoform X3. (736 aa)
Tcf7Transcription factor 7 isoform X10. (344 aa)
Bmp6Bone morphogenetic protein 6. (504 aa)
Dvl3Segment polarity protein dishevelled homolog DVL-3. (716 aa)
Birc5Baculoviral IAP repeat-containing protein 5. (142 aa)
PatjinaD-like protein. (1718 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (443 aa)
AregAmphiregulin. (245 aa)
Actrt2Actin-related protein T2; Belongs to the actin family. (377 aa)
LOC106002055Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (160 aa)
Tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (130 aa)
AfpAlpha-fetoprotein. (609 aa)
Crb2Protein crumbs homolog 2. (1256 aa)
AmotAngiomotin. (576 aa)
Cdh1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (881 aa)
Wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Pard3Partitioning defective 3 homolog isoform X1. (1294 aa)
Bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
Pard6aPartitioning defective 6 homolog alpha. (345 aa)
Sav1Protein salvador homolog 1. (384 aa)
BtrcF-box/WD repeat-containing protein 1A. (594 aa)
Dlg3Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (849 aa)
Ppp1cbSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
Trp53bp2Apoptosis-stimulating of p53 protein 2. (1123 aa)
Tcf7l1Transcription factor 7-like 1. (524 aa)
Tead1Transcriptional enhancer factor TEF-1 isoform X1. (436 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Ppp2r2dSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (288 aa)
Ppp1caSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
Nkd2Protein naked cuticle homolog 2. (442 aa)
Tcf7l2Transcription factor 7-like 2. (299 aa)
Lats2Serine/threonine-protein kinase LATS2. (1050 aa)
Ywhaz14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
Csnk1dCasein kinase I isoform delta isoform X1. (407 aa)
Limd1LIM domain-containing protein 1. (588 aa)
Tead3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (435 aa)
Serpine1Plasminogen activator inhibitor 1 isoform X2; Belongs to the serpin family. (401 aa)
Bmp2Bone morphogenetic protein 2. (398 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
Ppp1ccSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (312 aa)
Dlg2Disks large homolog 2 isoform X3. (870 aa)
Wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (573 aa)
Lrrc1Leucine-rich repeat-containing protein 1. (419 aa)
Tead2Transcriptional enhancer factor TEF-4. (245 aa)
Ctnna1LOW QUALITY PROTEIN: catenin alpha-1. (896 aa)
Csnk1eCasein kinase I isoform epsilon isoform X1; Belongs to the protein kinase superfamily. (416 aa)
Frmd6FERM domain-containing protein 6 isoform X2. (546 aa)
Fbxw11F-box/WD repeat-containing protein 11 isoform X1. (541 aa)
Bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Ctnna3Catenin alpha-3. (896 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (933 aa)
Smad4Mothers against decapentaplegic homolog. (528 aa)
Mob1bMOB kinase activator 1B. (216 aa)
Ppp2r1bProtein phosphatase 2 scaffold subunit Abeta. (584 aa)
Id1DNA-binding protein inhibitor ID-1. (183 aa)
Actl7aActin-like protein 7A; Belongs to the actin family. (439 aa)
Actl7bActin-like protein 7B; Belongs to the actin family. (418 aa)
Nkd1Protein naked cuticle homolog 1. (469 aa)
Gli2Zinc finger protein GLI2. (1549 aa)
Smad1Mothers against decapentaplegic homolog. (465 aa)
Ppp2cbSerine/threonine-protein phosphatase. (309 aa)
Rassf1Ras association domain-containing protein 1 isoform X1. (340 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
Lef1Lymphoid enhancer-binding factor 1. (370 aa)
Sox2Transcription factor SOX-2. (321 aa)
Wnt8aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Lats1Serine/threonine-protein kinase LATS1 isoform X1. (1129 aa)
Pard6bPartitioning defective 6 homolog beta. (352 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (656 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Wnt10aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
Pard6gPartitioning defective 6 homolog gamma. (361 aa)
Wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Ccnd3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa)
Gsk3bGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
Smad3Mothers against decapentaplegic homolog. (425 aa)
ENSDORP00000023068annotation not available (544 aa)
PrkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (538 aa)
Mob1aMOB kinase activator 1A. (216 aa)
Dlg4Disks large homolog 4; Belongs to the MAGUK family. (657 aa)
Ywhag14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
Yap1Transcriptional coactivator YAP1 isoform X1. (311 aa)
ActbActin, cytoplasmic 1. (375 aa)
Dlg5Disks large homolog 5; Belongs to the MAGUK family. (263 aa)
Wwc1Protein KIBRA. (1022 aa)
Myo15bUncharacterized protein LOC106001376; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2666 aa)
Axin2Axin-2. (837 aa)
Ccnd2G1/S-specific cyclin-D2; Belongs to the cyclin family. (224 aa)
Llgl2Lethal(2) giant larvae protein homolog 2 isoform X1. (1029 aa)
Bmp5Bone morphogenetic protein 5 isoform X1. (454 aa)
Fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
Tead4Transcriptional enhancer factor TEF-3. (427 aa)
LOC105997103Serine/threonine-protein phosphatase PP1-alpha catalytic subunit pseudogene. (308 aa)
Ppp2caSerine/threonine-protein phosphatase. (309 aa)
ENSDORP00000020585annotation not available (80 aa)
Stk3Serine/threonine-protein kinase 3. (491 aa)
Axin1Axin-1. (868 aa)
Sox3LOW QUALITY PROTEIN: transcription factor SOX-3. (369 aa)
LOC106002162Disks large homolog 4-like. (150 aa)
Ywhae14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa)
Fzd9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
Ccn2Connective tissue growth factor. (349 aa)
Ywhaq14-3-3 protein theta; Belongs to the 14-3-3 family. (125 aa)
AjubaLIM domain-containing protein ajuba isoform X1. (121 aa)
Snai2Zinc finger protein SNAI2. (261 aa)
Wnt2bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (490 aa)
Fzd8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (418 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ScribProtein scribble homolog. (1608 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Apc2Adenomatous polyposis coli protein 2. (2138 aa)
Ywhah14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
Wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
Fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
Ppp2r2bSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa)
ApcAdenomatous polyposis coli protein isoform X2. (2842 aa)
Ccnd1G1/S-specific cyclin-D1. (156 aa)
Ppp2r2aSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (431 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
Wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LOC105986097Bone morphogenetic protein 8A. (402 aa)
Ctnna2Catenin alpha-2 isoform X1. (954 aa)
Gdf5Growth/differentiation factor 5. (496 aa)
PrkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (518 aa)
Gdf6Growth/differentiation factor 6. (459 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
Tp73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (638 aa)
Id2DNA-binding protein inhibitor ID-2. (116 aa)
Rassf6Ras association domain-containing protein 6 isoform X1. (338 aa)
Mpp5MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (675 aa)
Wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
Dlg1Disks large homolog 1; Belongs to the MAGUK family. (834 aa)
AmhMuellerian-inhibiting factor. (547 aa)
Fzd7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LOC10599681914-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa)
Actl11Uncharacterized protein LOC105994564; Belongs to the actin family. (1215 aa)
Llgl1Lethal(2) giant larvae protein homolog 1 isoform X1. (1062 aa)
LOC106002396Transcription factor 7-like 2. (125 aa)
Ywhab14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa)
Smad7Mothers against decapentaplegic homolog. (427 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
LdahUPF0554 protein C2orf43 homolog isoform X1. (325 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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